BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

407 related articles for article (PubMed ID: 29192347)

  • 1. Pharmacogenetics of thiopurines for inflammatory bowel disease in East Asia: prospects for clinical application of NUDT15 genotyping.
    Kakuta Y; Kinouchi Y; Shimosegawa T
    J Gastroenterol; 2018 Feb; 53(2):172-180. PubMed ID: 29192347
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study.
    Kakuta Y; Kawai Y; Okamoto D; Takagawa T; Ikeya K; Sakuraba H; Nishida A; Nakagawa S; Miura M; Toyonaga T; Onodera K; Shinozaki M; Ishiguro Y; Mizuno S; Takahara M; Yanai S; Hokari R; Nakagawa T; Araki H; Motoya S; Naito T; Moroi R; Shiga H; Endo K; Kobayashi T; Naganuma M; Hiraoka S; Matsumoto T; Nakamura S; Nakase H; Hisamatsu T; Sasaki M; Hanai H; Andoh A; Nagasaki M; Kinouchi Y; Shimosegawa T; Masamune A; Suzuki Y;
    J Gastroenterol; 2018 Sep; 53(9):1065-1078. PubMed ID: 29923122
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Time to incorporate preemptive NUDT15 testing before starting thiopurines in inflammatory bowel disease in Asia and beyond: a review.
    Desai D; Jena A; Sharma V; Hibi T
    Expert Rev Clin Pharmacol; 2023; 16(7):643-653. PubMed ID: 37387532
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NUDT15 R139C causes thiopurine-induced early severe hair loss and leukopenia in Japanese patients with IBD.
    Kakuta Y; Naito T; Onodera M; Kuroha M; Kimura T; Shiga H; Endo K; Negoro K; Kinouchi Y; Shimosegawa T
    Pharmacogenomics J; 2016 Jun; 16(3):280-5. PubMed ID: 26076924
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Predictive role of NUDT15 variants on thiopurine-induced myelotoxicity in Asian inflammatory bowel disease patients.
    Sutiman N; Chen S; Ling KL; Chuah SW; Leong WF; Nadiger V; Tjai M; Choon Kong CS; Schwender BJ; Chan W; Shim HH; Lim WC; Khor CC; Cheung YB; Chowbay B
    Pharmacogenomics; 2018 Jan; 19(1):31-43. PubMed ID: 29210335
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Influences of thiopurine methyltransferase genotype and activity on thiopurine-induced leukopenia in Korean patients with inflammatory bowel disease: a retrospective cohort study.
    Kim JH; Cheon JH; Hong SS; Eun CS; Byeon JS; Hong SY; Kim BY; Kwon SH; Kim SW; Han DS; Yang SK; Kim WH
    J Clin Gastroenterol; 2010; 44(10):e242-8. PubMed ID: 20308917
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TPMT and NUDT15 polymorphisms in thiopurine induced leucopenia in inflammatory bowel disease: a prospective study from India.
    Grover N; Bhatia P; Kumar A; Singh M; Lad D; Mandavdhare HS; Samanta J; Prasad KK; Dutta U; Sharma V
    BMC Gastroenterol; 2021 Aug; 21(1):327. PubMed ID: 34425754
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacogenetic determinants of thiopurines in an Indian cohort.
    Naushad SM; Janaki Ramaiah M; Kutala VK; Hussain T; Alrokayan SA
    Pharmacol Rep; 2021 Feb; 73(1):278-287. PubMed ID: 32935219
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nucleoside diphosphate-linked moiety X-type motif 15 C415T variant as a predictor for thiopurine-induced toxicity in Indian patients.
    Shah SA; Paradkar M; Desai D; Ashavaid TF
    J Gastroenterol Hepatol; 2017 Mar; 32(3):620-624. PubMed ID: 27416873
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Influence of
    Kojima Y; Hirotsu Y; Omata W; Sugimori M; Takaoka S; Ashizawa H; Nakagomi K; Yoshimura D; Hosoda K; Suzuki Y; Mochizuki H; Omata M
    World J Gastroenterol; 2018 Jan; 24(4):511-518. PubMed ID: 29398872
    [TBL] [Abstract][Full Text] [Related]  

  • 11. NUDT15 variant is the most common variant associated with thiopurine-induced early leukopenia and alopecia in Korean pediatric patients with Crohn's disease.
    Lee YJ; Hwang EH; Park JH; Shin JH; Kang B; Kim SY
    Eur J Gastroenterol Hepatol; 2016 Apr; 28(4):475-8. PubMed ID: 26735160
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ITPA polymorphisms do not predict additional risk beyond TPMT and NUDT15 for thiopurine-induced cytopenia in inflammatory bowel disease.
    Jena A; Grover N; Bhatia P; Singh M; Lad D; Prasad KK; Singh H; Dutta U; Sharma V
    Rev Gastroenterol Mex (Engl Ed); 2024; 89(1):25-30. PubMed ID: 36707393
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combined Detection of NUDT15 Variants Could Highly Predict Thiopurine-induced Leukopenia in Chinese Patients with Inflammatory Bowel Disease: A Multicenter Analysis.
    Chao K; Wang X; Cao Q; Qian J; Wu K; Zhu X; Yang H; Liang J; Lin L; Huang Z; Zhang Y; Huang Y; Sun Y; Xue X; Huang M; Hu P; Lan P; Gao X
    Inflamm Bowel Dis; 2017 Sep; 23(9):1592-1599. PubMed ID: 28570428
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Long-term effect of NUDT15 R139C on hematologic indices in inflammatory bowel disease patients treated with thiopurine.
    Akiyama S; Matsuoka K; Fukuda K; Hamada S; Shimizu M; Nanki K; Mizuno S; Kiyohara H; Arai M; Sugimoto S; Iwao Y; Ogata H; Hisamatsu T; Naganuma M; Motobayashi M; Suzuki K; Takenaka K; Fujii T; Saito E; Nagahori M; Ohtsuka K; Mochizuki M; Watanabe M; Hashiguchi M; Kanai T
    J Gastroenterol Hepatol; 2019 Oct; 34(10):1751-1757. PubMed ID: 31045285
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity.
    Moriyama T; Nishii R; Perez-Andreu V; Yang W; Klussmann FA; Zhao X; Lin TN; Hoshitsuki K; Nersting J; Kihira K; Hofmann U; Komada Y; Kato M; McCorkle R; Li L; Koh K; Najera CR; Kham SK; Isobe T; Chen Z; Chiew EK; Bhojwani D; Jeffries C; Lu Y; Schwab M; Inaba H; Pui CH; Relling MV; Manabe A; Hori H; Schmiegelow K; Yeoh AE; Evans WE; Yang JJ
    Nat Genet; 2016 Apr; 48(4):367-73. PubMed ID: 26878724
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nucleoside diphosphate-linked moiety X-type motif 15 R139C genotypes impact 6-thioguanine nucleotide cut-off levels to predict thiopurine-induced leukopenia in Crohn's disease patients.
    Zhu X; Chao K; Li M; Xie W; Zheng H; Zhang JX; Hu PJ; Huang M; Gao X; Wang XD
    World J Gastroenterol; 2019 Oct; 25(38):5850-5861. PubMed ID: 31636477
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NUDT15 and TPMT genetic polymorphisms are related to 6-mercaptopurine intolerance in children treated for acute lymphoblastic leukemia at the Children's Cancer Center of Lebanon.
    Zgheib NK; Akika R; Mahfouz R; Aridi CA; Ghanem KM; Saab R; Abboud MR; Tarek N; El Solh H; Muwakkit SA
    Pediatr Blood Cancer; 2017 Jan; 64(1):146-150. PubMed ID: 27577869
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparison of
    Wang HH; He Y; Wang HX; Liao CL; Peng Y; Tao LJ; Zhang W; Yang HX
    World J Gastroenterol; 2018 Feb; 24(8):941-948. PubMed ID: 29491687
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel variants in
    Moriyama T; Yang YL; Nishii R; Ariffin H; Liu C; Lin TN; Yang W; Lin DT; Yu CH; Kham S; Pui CH; Evans WE; Jeha S; Relling MV; Yeoh AE; Yang JJ
    Blood; 2017 Sep; 130(10):1209-1212. PubMed ID: 28659275
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Update on thiopurine pharmacogenetics in inflammatory bowel disease.
    Roberts RL; Barclay ML
    Pharmacogenomics; 2015 Jul; 16(8):891-903. PubMed ID: 26067482
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.