210 related articles for article (PubMed ID: 29196611)
1. Cell signaling abnormalities in cardiomyopathy caused by lamin A/C gene mutations.
Worman HJ
Biochem Soc Trans; 2018 Feb; 46(1):37-42. PubMed ID: 29196611
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of extracellular signal-regulated kinase signaling to prevent cardiomyopathy caused by mutation in the gene encoding A-type lamins.
Muchir A; Shan J; Bonne G; Lehnart SE; Worman HJ
Hum Mol Genet; 2009 Jan; 18(2):241-7. PubMed ID: 18927124
[TBL] [Abstract][Full Text] [Related]
3. Dual specificity phosphatase 4 mediates cardiomyopathy caused by lamin A/C (LMNA) gene mutation.
Choi JC; Wu W; Muchir A; Iwata S; Homma S; Worman HJ
J Biol Chem; 2012 Nov; 287(48):40513-24. PubMed ID: 23048029
[TBL] [Abstract][Full Text] [Related]
4. Targeting Mitogen-Activated Protein Kinase Signaling in Mouse Models of Cardiomyopathy Caused by Lamin A/C Gene Mutations.
Muchir A; Worman HJ
Methods Enzymol; 2016; 568():557-80. PubMed ID: 26795484
[TBL] [Abstract][Full Text] [Related]
5. Gene expression profiling of fibroblasts in a family with LMNA-related cardiomyopathy reveals molecular pathways implicated in disease pathogenesis.
Widyastuti HP; Norden-Krichmar TM; Grosberg A; Zaragoza MV
BMC Med Genet; 2020 Jul; 21(1):152. PubMed ID: 32698886
[TBL] [Abstract][Full Text] [Related]
6. Pharmacological inhibition of c-Jun N-terminal kinase signaling prevents cardiomyopathy caused by mutation in LMNA gene.
Wu W; Shan J; Bonne G; Worman HJ; Muchir A
Biochim Biophys Acta; 2010; 1802(7-8):632-8. PubMed ID: 20388542
[TBL] [Abstract][Full Text] [Related]
7. Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival.
Choi JC; Wu W; Phillips E; Plevin R; Sera F; Homma S; Worman HJ
Hum Mol Genet; 2018 Jul; 27(13):2290-2305. PubMed ID: 29668927
[TBL] [Abstract][Full Text] [Related]
8. Skeletal and Cardiac Muscle Disorders Caused by Mutations in Genes Encoding Intermediate Filament Proteins.
Maggi L; Mavroidis M; Psarras S; Capetanaki Y; Lattanzi G
Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33923914
[TBL] [Abstract][Full Text] [Related]
9. DNA Damage Response/TP53 Pathway Is Activated and Contributes to the Pathogenesis of Dilated Cardiomyopathy Associated With LMNA (Lamin A/C) Mutations.
Chen SN; Lombardi R; Karmouch J; Tsai JY; Czernuszewicz G; Taylor MRG; Mestroni L; Coarfa C; Gurha P; Marian AJ
Circ Res; 2019 Mar; 124(6):856-873. PubMed ID: 30696354
[TBL] [Abstract][Full Text] [Related]
10. Depletion of extracellular signal-regulated kinase 1 in mice with cardiomyopathy caused by lamin A/C gene mutation partially prevents pathology before isoenzyme activation.
Wu W; Iwata S; Homma S; Worman HJ; Muchir A
Hum Mol Genet; 2014 Jan; 23(1):1-11. PubMed ID: 23933734
[TBL] [Abstract][Full Text] [Related]
11. ERK1/2 directly acts on CTGF/CCN2 expression to mediate myocardial fibrosis in cardiomyopathy caused by mutations in the lamin A/C gene.
Chatzifrangkeskou M; Le Dour C; Wu W; Morrow JP; Joseph LC; Beuvin M; Sera F; Homma S; Vignier N; Mougenot N; Bonne G; Lipson KE; Worman HJ; Muchir A
Hum Mol Genet; 2016 Jun; 25(11):2220-2233. PubMed ID: 27131347
[TBL] [Abstract][Full Text] [Related]
12. Mitogen-activated protein kinase inhibitors improve heart function and prevent fibrosis in cardiomyopathy caused by mutation in lamin A/C gene.
Wu W; Muchir A; Shan J; Bonne G; Worman HJ
Circulation; 2011 Jan; 123(1):53-61. PubMed ID: 21173351
[TBL] [Abstract][Full Text] [Related]
13. Mitogen-activated protein kinase kinase 1/2 inhibition and angiotensin II converting inhibition in mice with cardiomyopathy caused by lamin A/C gene mutation.
Muchir A; Wu W; Sera F; Homma S; Worman HJ
Biochem Biophys Res Commun; 2014 Oct; 452(4):958-61. PubMed ID: 25218145
[TBL] [Abstract][Full Text] [Related]
14. Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation.
Choi JC; Muchir A; Wu W; Iwata S; Homma S; Morrow JP; Worman HJ
Sci Transl Med; 2012 Jul; 4(144):144ra102. PubMed ID: 22837537
[TBL] [Abstract][Full Text] [Related]
15. Mitogen-activated protein kinase inhibitor regulation of heart function and fibrosis in cardiomyopathy caused by lamin A/C gene mutation.
Muchir A; Wu W; Worman HJ
Trends Cardiovasc Med; 2010 Oct; 20(7):217-21. PubMed ID: 22293021
[TBL] [Abstract][Full Text] [Related]
16. Ryanodine receptor remodeling in cardiomyopathy and muscular dystrophy caused by lamin A/C gene mutation.
Dridi H; Wu W; Reiken SR; Ofer RM; Liu Y; Yuan Q; Sittenfeld L; Kushner J; Muchir A; Worman HJ; Marks AR
Hum Mol Genet; 2021 Feb; 29(24):3919-3934. PubMed ID: 33388782
[TBL] [Abstract][Full Text] [Related]
17. Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease.
Wolf CM; Wang L; Alcalai R; Pizard A; Burgon PG; Ahmad F; Sherwood M; Branco DM; Wakimoto H; Fishman GI; See V; Stewart CL; Conner DA; Berul CI; Seidman CE; Seidman JG
J Mol Cell Cardiol; 2008 Feb; 44(2):293-303. PubMed ID: 18182166
[TBL] [Abstract][Full Text] [Related]
18. Reactivation of autophagy ameliorates LMNA cardiomyopathy.
Choi JC; Worman HJ
Autophagy; 2013 Jan; 9(1):110-1. PubMed ID: 23044536
[TBL] [Abstract][Full Text] [Related]
19. Rapamycin reverses elevated mTORC1 signaling in lamin A/C-deficient mice, rescues cardiac and skeletal muscle function, and extends survival.
Ramos FJ; Chen SC; Garelick MG; Dai DF; Liao CY; Schreiber KH; MacKay VL; An EH; Strong R; Ladiges WC; Rabinovitch PS; Kaeberlein M; Kennedy BK
Sci Transl Med; 2012 Jul; 4(144):144ra103. PubMed ID: 22837538
[TBL] [Abstract][Full Text] [Related]
20. mTOR Inhibition Prolongs Survival and Has Beneficial Effects on Heart Function After Onset of Lamin A/C Gene Mutation Cardiomyopathy in Mice.
Wu W; Jin Q; Östlund C; Tanji K; Shin JY; Han J; Leu CS; Kushner J; Worman HJ
Circ Heart Fail; 2024 Apr; 17(4):e011110. PubMed ID: 38567527
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]