BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

362 related articles for article (PubMed ID: 29199977)

  • 21. Nucleotide binding and GTP hydrolysis by the 21-kDa product of the c-H-ras gene as monitored by proton-NMR spectroscopy.
    Löw A; Sprinzl M; Limmer S
    Eur J Biochem; 1993 Apr; 213(2):781-8. PubMed ID: 8386636
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Structural basis for the unique biological function of small GTPase RHEB.
    Yu Y; Li S; Xu X; Li Y; Guan K; Arnold E; Ding J
    J Biol Chem; 2005 Apr; 280(17):17093-100. PubMed ID: 15728574
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Ab initio study of the role of lysine 16 for the molecular switching mechanism of Ras protein p21.
    Futatsugi N; Hata M; Hoshino T; Tsuda M
    Biophys J; 1999 Dec; 77(6):3287-92. PubMed ID: 10585950
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP.
    Tong LA; de Vos AM; Milburn MV; Kim SH
    J Mol Biol; 1991 Feb; 217(3):503-16. PubMed ID: 1899707
    [TBL] [Abstract][Full Text] [Related]  

  • 25. High frequency (139.5 GHz) electron paramagnetic resonance characterization of Mn(II)-H2(17)O interactions in GDP and GTP forms of p21 ras.
    Bellew BF; Halkides CJ; Gerfen GJ; Griffin RG; Singel DJ
    Biochemistry; 1996 Sep; 35(37):12186-93. PubMed ID: 8810926
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Mapping the nucleotide-dependent conformational change of human N-ras p21 in solution by heteronuclear-edited proton-observed NMR methods.
    Hu JS; Redfield AG
    Biochemistry; 1993 Jul; 32(26):6763-72. PubMed ID: 8329399
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Regional polysterism in the GTP-bound form of the human c-Ha-Ras protein.
    Ito Y; Yamasaki K; Iwahara J; Terada T; Kamiya A; Shirouzu M; Muto Y; Kawai G; Yokoyama S; Laue ED; Wälchli M; Shibata T; Nishimura S; Miyazawa T
    Biochemistry; 1997 Jul; 36(30):9109-19. PubMed ID: 9230043
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Ras-catalyzed hydrolysis of GTP: a new perspective from model studies.
    Maegley KA; Admiraal SJ; Herschlag D
    Proc Natl Acad Sci U S A; 1996 Aug; 93(16):8160-6. PubMed ID: 8710841
    [TBL] [Abstract][Full Text] [Related]  

  • 29. GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site.
    Lu S; Banerjee A; Jang H; Zhang J; Gaponenko V; Nussinov R
    J Biol Chem; 2015 Nov; 290(48):28887-900. PubMed ID: 26453300
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis.
    Coleman DE; Berghuis AM; Lee E; Linder ME; Gilman AG; Sprang SR
    Science; 1994 Sep; 265(5177):1405-12. PubMed ID: 8073283
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue.
    Ihara K; Muraguchi S; Kato M; Shimizu T; Shirakawa M; Kuroda S; Kaibuchi K; Hakoshima T
    J Biol Chem; 1998 Apr; 273(16):9656-66. PubMed ID: 9545299
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Calculation of pathways for the conformational transition between the GTP- and GDP-bound states of the Ha-ras-p21 protein: calculations with explicit solvent simulations and comparison with calculations in vacuum.
    Diaz JF; Wroblowski B; Schlitter J; Engelborghs Y
    Proteins; 1997 Jul; 28(3):434-51. PubMed ID: 9223188
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Crystal structures of the state 1 conformations of the GTP-bound H-Ras protein and its oncogenic G12V and Q61L mutants.
    Muraoka S; Shima F; Araki M; Inoue T; Yoshimoto A; Ijiri Y; Seki N; Tamura A; Kumasaka T; Yamamoto M; Kataoka T
    FEBS Lett; 2012 Jun; 586(12):1715-8. PubMed ID: 22584058
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Dissection of the GTPase mechanism of Ras protein by MD analysis of Ras mutants.
    Friedman ZY; Devary Y
    Proteins; 2005 May; 59(3):528-33. PubMed ID: 15789417
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Rap1A antagonizes the ability of Ras and Ras-Gap to inhibit muscarinic K+ channels.
    Yatani A; Quilliam LA; Brown AM; Bokoch GM
    J Biol Chem; 1991 Nov; 266(33):22222-6. PubMed ID: 1939245
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Millisecond Allosteric Dynamics of Activated Ras Reproduced with a Slowly Hydrolyzable GTP Analogue.
    Chen X; Gao H; Long D
    Chembiochem; 2021 Mar; 22(6):1079-1083. PubMed ID: 33140496
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Conformation change of effector-region residues in antiparallel beta-sheet of human c-Ha-ras protein on GDP----GTP gamma S exchange: a two-dimensional NMR study.
    Yamasaki K; Kawai G; Ito Y; Muto Y; Fujita J; Miyazawa T; Nishimura S; Yokoyama S
    Biochem Biophys Res Commun; 1989 Aug; 162(3):1054-62. PubMed ID: 2669742
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The mechanism of Ras GTPase activation by neurofibromin.
    Phillips RA; Hunter JL; Eccleston JF; Webb MR
    Biochemistry; 2003 Apr; 42(13):3956-65. PubMed ID: 12667087
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Electrostatic control of GTP and GDP binding in the oncoprotein p21ras.
    Muegge I; Schweins T; Langen R; Warshel A
    Structure; 1996 Apr; 4(4):475-89. PubMed ID: 8740369
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis.
    Schlichting I; Almo SC; Rapp G; Wilson K; Petratos K; Lentfer A; Wittinghofer A; Kabsch W; Pai EF; Petsko GA
    Nature; 1990 May; 345(6273):309-15. PubMed ID: 2111463
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 19.