These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

327 related articles for article (PubMed ID: 29202464)

  • 1. Hedgehog signaling drives medulloblastoma growth via CDK6.
    Raleigh DR; Choksi PK; Krup AL; Mayer W; Santos N; Reiter JF
    J Clin Invest; 2018 Jan; 128(1):120-124. PubMed ID: 29202464
    [TBL] [Abstract][Full Text] [Related]  

  • 2. mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma.
    Wu CC; Hou S; Orr BA; Kuo BR; Youn YH; Ong T; Roth F; Eberhart CG; Robinson GW; Solecki DJ; Taketo MM; Gilbertson RJ; Roussel MF; Han YG
    Dev Cell; 2017 Dec; 43(6):673-688.e5. PubMed ID: 29103956
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The stem cell-associated transcription co-factor, ZNF521, interacts with GLI1 and GLI2 and enhances the activity of the Sonic hedgehog pathway.
    Scicchitano S; Giordano M; Lucchino V; Montalcini Y; Chiarella E; Aloisio A; Codispoti B; Zoppoli P; Melocchi V; Bianchi F; De Smaele E; Mesuraca M; Morrone G; Bond HM
    Cell Death Dis; 2019 Sep; 10(10):715. PubMed ID: 31558698
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Smoothened-activating lipids drive resistance to CDK4/6 inhibition in Hedgehog-associated medulloblastoma cells and preclinical models.
    Daggubati V; Hochstelter J; Bommireddy A; Choudhury A; Krup AL; Kaur P; Tong P; Li A; Xu L; Reiter JF; Raleigh DR
    J Clin Invest; 2021 Mar; 131(6):. PubMed ID: 33476305
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prostaglandin E1 Inhibits
    Wu F; Zhang C; Zhao C; Wu H; Teng Z; Jiang T; Wang Y
    Cancer Res; 2020 Jul; 80(13):2818-2832. PubMed ID: 32371475
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hedgehog/GLI signaling activates suppressor of cytokine signaling 1 (SOCS1) in epidermal and neural tumor cells.
    Laner-Plamberger S; Wolff F; Kaser-Eichberger A; Swierczynski S; Hauser-Kronberger C; Frischauf AM; Eichberger T
    PLoS One; 2013; 8(9):e75317. PubMed ID: 24058673
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells.
    Scheidt T; Alka O; Gonczarowska-Jorge H; Gruber W; Rathje F; Dell'Aica M; Rurik M; Kohlbacher O; Zahedi RP; Aberger F; Huber CG
    Cell Commun Signal; 2020 Jun; 18(1):99. PubMed ID: 32576205
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Histone deacetylase 6 represents a novel drug target in the oncogenic Hedgehog signaling pathway.
    Dhanyamraju PK; Holz PS; Finkernagel F; Fendrich V; Lauth M
    Mol Cancer Ther; 2015 Mar; 14(3):727-39. PubMed ID: 25552369
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hedgehog signaling promotes medulloblastoma survival via Bc/II.
    Bar EE; Chaudhry A; Farah MH; Eberhart CG
    Am J Pathol; 2007 Jan; 170(1):347-55. PubMed ID: 17200206
    [TBL] [Abstract][Full Text] [Related]  

  • 10. β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma.
    Zinke J; Schneider FT; Harter PN; Thom S; Ziegler N; Toftgård R; Plate KH; Liebner S
    Mol Cancer; 2015 Feb; 14(1):17. PubMed ID: 25645196
    [TBL] [Abstract][Full Text] [Related]  

  • 11. YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells.
    Dey A; Robitaille M; Remke M; Maier C; Malhotra A; Gregorieff A; Wrana JL; Taylor MD; Angers S; Kenney AM
    Oncogene; 2016 Aug; 35(32):4256-68. PubMed ID: 26725322
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector.
    Kim J; Lee JJ; Kim J; Gardner D; Beachy PA
    Proc Natl Acad Sci U S A; 2010 Jul; 107(30):13432-7. PubMed ID: 20624968
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Histone acetyltransferase PCAF is required for Hedgehog-Gli-dependent transcription and cancer cell proliferation.
    Malatesta M; Steinhauer C; Mohammad F; Pandey DP; Squatrito M; Helin K
    Cancer Res; 2013 Oct; 73(20):6323-33. PubMed ID: 23943798
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma.
    De Smaele E; Di Marcotullio L; Moretti M; Pelloni M; Occhione MA; Infante P; Cucchi D; Greco A; Pietrosanti L; Todorovic J; Coni S; Canettieri G; Ferretti E; Bei R; Maroder M; Screpanti I; Gulino A
    Neoplasia; 2011 Apr; 13(4):374-85. PubMed ID: 21472142
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CAT3, a novel agent for medulloblastoma and glioblastoma treatment, inhibits tumor growth by disrupting the Hedgehog signaling pathway.
    Chen J; Lv H; Hu J; Ji M; Xue N; Li C; Ma S; Zhou Q; Lin B; Li Y; Yu S; Chen X
    Cancer Lett; 2016 Oct; 381(2):391-403. PubMed ID: 27495899
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CDK7 inhibition suppresses aberrant hedgehog pathway and overcomes resistance to smoothened antagonists.
    Liu F; Jiang W; Sui Y; Meng W; Hou L; Li T; Li M; Zhang L; Mo J; Wang J; Zhao Y; Zhang L; Ma J; Tang Y
    Proc Natl Acad Sci U S A; 2019 Jun; 116(26):12986-12995. PubMed ID: 31182587
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Statins Synergize with Hedgehog Pathway Inhibitors for Treatment of Medulloblastoma.
    Gordon RE; Zhang L; Peri S; Kuo YM; Du F; Egleston BL; Ng JMY; Andrews AJ; Astsaturov I; Curran T; Yang ZJ
    Clin Cancer Res; 2018 Mar; 24(6):1375-1388. PubMed ID: 29437795
    [No Abstract]   [Full Text] [Related]  

  • 18. RITA downregulates Hedgehog-GLI in medulloblastoma and rhabdomyosarcoma via JNK-dependent but p53-independent mechanism.
    Azatyan A; Gallo-Oller G; Diao Y; Selivanova G; Johnsen JI; Zaphiropoulos PG
    Cancer Lett; 2019 Feb; 442():341-350. PubMed ID: 30447254
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Saikosaponin B1 and Saikosaponin D inhibit tumor growth in medulloblastoma allograft mice via inhibiting the Hedgehog signaling pathway.
    Luo J; Wang J; Yang J; Huang W; Liu J; Tan W; Xin H
    J Nat Med; 2022 Jun; 76(3):584-593. PubMed ID: 35171398
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma.
    Purzner T; Purzner J; Buckstaff T; Cozza G; Gholamin S; Rusert JM; Hartl TA; Sanders J; Conley N; Ge X; Langan M; Ramaswamy V; Ellis L; Litzenburger U; Bolin S; Theruvath J; Nitta R; Qi L; Li XN; Li G; Taylor MD; Wechsler-Reya RJ; Pinna LA; Cho YJ; Fuller MT; Elias JE; Scott MP
    Sci Signal; 2018 Sep; 11(547):. PubMed ID: 30206138
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.