BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 29207597)

  • 1. Inhibition of Miro1 disturbs mitophagy and pancreatic β-cell function interfering insulin release via IRS-Akt-Foxo1 in diabetes.
    Chen L; Liu C; Gao J; Xie Z; Chan LWC; Keating DJ; Yang Y; Sun J; Zhou F; Wei Y; Men X; Yang S
    Oncotarget; 2017 Oct; 8(53):90693-90705. PubMed ID: 29207597
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Miro1-mediated mitochondrial dysfunction under high nutrient stress is linked to NOD-like receptor 3 (NLRP3)-dependent inflammatory responses in rat pancreatic beta cells.
    Gao J; Sang M; Zhang X; Zheng T; Pan J; Dai M; Zhou L; Yang S
    Free Radic Biol Med; 2015 Dec; 89():322-32. PubMed ID: 26427885
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Obesity-Induced Regulator of Calcineurin 1 Overexpression Leads to β-Cell Failure Through Mitophagy Pathway Inhibition.
    Li X; Chan LWC; Li X; Liu C; Yang G; Gao J; Dai M; Wang Y; Xie Z; Liu J; Zhou F; Zheng T; Feng D; Guo S; Li H; Sun K; Yang S
    Antioxid Redox Signal; 2020 Mar; 32(7):413-428. PubMed ID: 31822118
    [No Abstract]   [Full Text] [Related]  

  • 4. Lipotoxicity-polarised macrophage-derived exosomes regulate mitochondrial fitness through Miro1-mediated mitophagy inhibition and contribute to type 2 diabetes development in mice.
    Li JM; Li X; Chan LWC; Hu R; Zheng T; Li H; Yang S
    Diabetologia; 2023 Dec; 66(12):2368-2386. PubMed ID: 37615690
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of p53 preserves Parkin-mediated mitophagy and pancreatic β-cell function in diabetes.
    Hoshino A; Ariyoshi M; Okawa Y; Kaimoto S; Uchihashi M; Fukai K; Iwai-Kanai E; Ikeda K; Ueyama T; Ogata T; Matoba S
    Proc Natl Acad Sci U S A; 2014 Feb; 111(8):3116-21. PubMed ID: 24516131
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A new beta cell-specific mitophagy reporter mouse shows that metabolic stress leads to accumulation of dysfunctional mitochondria despite increased mitophagy.
    Aoyagi K; Yamashita SI; Akimoto Y; Nishiwaki C; Nakamichi Y; Udagawa H; Abe M; Sakimura K; Kanki T; Ohara-Imaizumi M
    Diabetologia; 2023 Jan; 66(1):147-162. PubMed ID: 36181536
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mitochondrial transcription factor B2 is essential for mitochondrial and cellular function in pancreatic β-cells.
    Nicholas LM; Valtat B; Medina A; Andersson L; Abels M; Mollet IG; Jain D; Eliasson L; Wierup N; Fex M; Mulder H
    Mol Metab; 2017 Jul; 6(7):651-663. PubMed ID: 28702322
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes.
    Sharoyko VV; Abels M; Sun J; Nicholas LM; Mollet IG; Stamenkovic JA; Göhring I; Malmgren S; Storm P; Fadista J; Spégel P; Metodiev MD; Larsson NG; Eliasson L; Wierup N; Mulder H
    Hum Mol Genet; 2014 Nov; 23(21):5733-49. PubMed ID: 24916378
    [TBL] [Abstract][Full Text] [Related]  

  • 9. High glucose induces suppression of insulin signalling and apoptosis via upregulation of endogenous IL-1beta and suppressor of cytokine signalling-1 in mouse pancreatic beta cells.
    Venieratos PD; Drossopoulou GI; Kapodistria KD; Tsilibary EC; Kitsiou PV
    Cell Signal; 2010 May; 22(5):791-800. PubMed ID: 20067833
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mitophagy protects β cells from inflammatory damage in diabetes.
    Sidarala V; Pearson GL; Parekh VS; Thompson B; Christen L; Gingerich MA; Zhu J; Stromer T; Ren J; Reck EC; Chai B; Corbett JA; Mandrup-Poulsen T; Satin LS; Soleimanpour SA
    JCI Insight; 2020 Dec; 5(24):. PubMed ID: 33232298
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alterations in growth and apoptosis of insulin receptor substrate-1-deficient beta-cells.
    Hennige AM; Ozcan U; Okada T; Jhala US; Schubert M; White MF; Kulkarni RN
    Am J Physiol Endocrinol Metab; 2005 Aug; 289(2):E337-46. PubMed ID: 15827066
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Peroxisome proliferator-activated receptorβ/δ activation is essential for modulating p-Foxo1/Foxo1 status in functional insulin-positive cell differentiation.
    Li L; Li T; Zhang Y; Pan Z; Wu B; Huang X; Zhang Y; Mei Y; Ge L; Shen G; Ge RS; Zhu D; Lou Y
    Cell Death Dis; 2015 Apr; 6(4):e1715. PubMed ID: 25855963
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis.
    Martinez SC; Tanabe K; Cras-Méneur C; Abumrad NA; Bernal-Mizrachi E; Permutt MA
    Diabetes; 2008 Apr; 57(4):846-59. PubMed ID: 18174526
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stromal cell derived factor-1 (SDF-1)/CXCL12 attenuates diabetes in mice and promotes pancreatic beta-cell survival by activation of the prosurvival kinase Akt.
    Yano T; Liu Z; Donovan J; Thomas MK; Habener JF
    Diabetes; 2007 Dec; 56(12):2946-57. PubMed ID: 17878289
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells.
    Bouzakri K; Ribaux P; Tomas A; Parnaud G; Rickenbach K; Halban PA
    Diabetes; 2008 May; 57(5):1195-204. PubMed ID: 18276765
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Puerarin protects pancreatic β-cell survival via PI3K/Akt signaling pathway.
    Li Z; Shangguan Z; Liu Y; Wang J; Li X; Yang S; Liu S
    J Mol Endocrinol; 2014 Aug; 53(1):71-9. PubMed ID: 24827001
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sphingosine 1-phosphate counteracts insulin signaling in pancreatic β-cells via the sphingosine 1-phosphate receptor subtype 2.
    Japtok L; Schmitz EI; Fayyaz S; Krämer S; Hsu LJ; Kleuser B
    FASEB J; 2015 Aug; 29(8):3357-69. PubMed ID: 25911610
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Loss of fibroblast growth factor 21 action induces insulin resistance, pancreatic islet hyperplasia and dysfunction in mice.
    So WY; Cheng Q; Xu A; Lam KS; Leung PS
    Cell Death Dis; 2015 Mar; 6(3):e1707. PubMed ID: 25811804
    [TBL] [Abstract][Full Text] [Related]  

  • 19. beta-cell failure in diabetes and preservation by clinical treatment.
    Wajchenberg BL
    Endocr Rev; 2007 Apr; 28(2):187-218. PubMed ID: 17353295
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Curcumin attenuates palmitate-induced apoptosis in MIN6 pancreatic β-cells through PI3K/Akt/FoxO1 and mitochondrial survival pathways.
    Hao F; Kang J; Cao Y; Fan S; Yang H; An Y; Pan Y; Tie L; Li X
    Apoptosis; 2015 Nov; 20(11):1420-32. PubMed ID: 26330141
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.