BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 29208522)

  • 1. Discovery of new GSK-3β inhibitors through structure-based virtual screening.
    Dou X; Jiang L; Wang Y; Jin H; Liu Z; Zhang L
    Bioorg Med Chem Lett; 2018 Jan; 28(2):160-166. PubMed ID: 29208522
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of Coumarin Derivatives as Versatile Scaffolds for GSK-3β Enzyme Inhibition.
    Francisco CS; Javarini CL; de S Barcelos I; Morais PAB; de Paula H; de S Borges W; Neto ÁC; Lacerda V
    Curr Top Med Chem; 2020; 20(2):153-160. PubMed ID: 31648640
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of thiazolidin-4-one analogue as selective GSK-3β inhibitor through structure based virtual screening.
    Choudhary BS; Sukanya ; Mehta P; Bach S; Ruchaud S; Robert T; Josselin B; Filipek S; Malik R
    Bioorg Med Chem Lett; 2021 Nov; 52():128375. PubMed ID: 34560262
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biological evaluation and energetic analyses of novel GSK-3β inhibitors.
    Zhang D; Liu L; Pang L; Jin Q; Ke K; Hu M; Yang J; Ma W; Xie H; Chen X
    J Cell Biochem; 2018 Apr; 119(4):3510-3518. PubMed ID: 29144001
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification and in vitro evaluation of new leads as selective and competitive glycogen synthase kinase-3β inhibitors through ligand and structure based drug design.
    Darshit BS; Balaji B; Rani P; Ramanathan M
    J Mol Graph Model; 2014 Sep; 53():31-47. PubMed ID: 25064440
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The discovery of novel benzothiazinones as highly selective non-ATP competitive glycogen synthase kinase 3β inhibitors for the treatment of ovarian cancer.
    Gao Y; Ye DY; Zhou WC; Chu Y
    Eur J Med Chem; 2017 Jul; 135():370-381. PubMed ID: 28460311
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel oxindole/benzofuran hybrids as potential dual CDK2/GSK-3β inhibitors targeting breast cancer: design, synthesis, biological evaluation, and
    Eldehna WM; Al-Rashood ST; Al-Warhi T; Eskandrani RO; Alharbi A; El Kerdawy AM
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):270-285. PubMed ID: 33327806
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of novel 2-(4-aryl-2-methylpiperazin-1-yl)-pyrimidin-4-ones as glycogen synthase kinase-3β inhibitors.
    Kohara T; Nakayama K; Watanabe K; Kusaka SI; Sakai D; Tanaka H; Fukunaga K; Sunada S; Nabeno M; Saito KI; Eguchi JI; Mori A; Tanaka S; Bessho T; Takiguchi-Hayashi K; Horikawa T
    Bioorg Med Chem Lett; 2017 Aug; 27(16):3733-3738. PubMed ID: 28712706
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and biological evaluation of harmine derivatives as potent GSK-3β/DYRK1A dual inhibitors for the treatment of Alzheimer's disease.
    Liu W; Liu X; Tian L; Gao Y; Liu W; Chen H; Jiang X; Xu Z; Ding H; Zhao Q
    Eur J Med Chem; 2021 Oct; 222():113554. PubMed ID: 34098466
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, Synthesis and in Vitro Tumor Cytotoxicity Evaluation of 3,5-Diamino-N-substituted Benzamide Derivatives as Novel GSK-3β Small Molecule Inhibitors.
    Zhou Y; Zhang L; Fu X; Jiang Z; Tong R; Shi J; Li J; Zhong L
    Chem Biodivers; 2019 Sep; 16(9):e1900304. PubMed ID: 31338947
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A new protocol for predicting novel GSK-3β ATP competitive inhibitors.
    Fang J; Huang D; Zhao W; Ge H; Luo HB; Xu J
    J Chem Inf Model; 2011 Jun; 51(6):1431-8. PubMed ID: 21615159
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of pyrimidin-4-one-1,2,3-triazole conjugates as glycogen synthase kinase-3β inhibitors with anti-depressant activity.
    Khan I; Tantray MA; Hamid H; Alam MS; Kalam A; Hussain F; Dhulap A
    Bioorg Chem; 2016 Oct; 68():41-55. PubMed ID: 27454617
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amaryllidaceae Alkaloids as Potential Glycogen Synthase Kinase-3β Inhibitors.
    Hulcová D; Breiterová K; Siatka T; Klímová K; Davani L; Šafratová M; Hošťálková A; De Simone A; Andrisano V; Cahlíková L
    Molecules; 2018 Mar; 23(4):. PubMed ID: 29561817
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Triazolotriazine-Based Dual GSK-3β/CK-1δ Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition.
    Redenti S; Marcovich I; De Vita T; Pérez C; De Zorzi R; Demitri N; Perez DI; Bottegoni G; Bisignano P; Bissaro M; Moro S; Martinez A; Storici P; Spalluto G; Cavalli A; Federico S
    ChemMedChem; 2019 Feb; 14(3):310-314. PubMed ID: 30548443
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of novel 2-(3-phenylpiperazin-1-yl)-pyrimidin-4-ones as glycogen synthase kinase-3β inhibitors.
    Usui Y; Uehara F; Hiki S; Watanabe K; Tanaka H; Shouda A; Yokoshima S; Aritomo K; Adachi T; Fukunaga K; Sunada S; Nabeno M; Saito KI; Eguchi JI; Yamagami K; Asano S; Tanaka S; Yuki S; Yoshii N; Fujimura M; Horikawa T
    Bioorg Med Chem Lett; 2017 Aug; 27(16):3726-3732. PubMed ID: 28712708
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A physicochemical descriptor based method for effective and rapid screening of dual inhibitors against BACE-1 and GSK-3β as targets for Alzheimer's disease.
    Kumar A; Srivastava G; Sharma A
    Comput Biol Chem; 2017 Dec; 71():1-9. PubMed ID: 28950235
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of novel scaffold of benzothiazepinones as non-ATP competitive glycogen synthase kinase-3β inhibitors through virtual screening.
    Zhang P; Hu HR; Huang ZH; Lei JY; Chu Y; Ye DY
    Bioorg Med Chem Lett; 2012 Dec; 22(23):7232-6. PubMed ID: 23099099
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery and Evaluation of Enantiopure 9
    Andreev S; Pantsar T; El-Gokha A; Ansideri F; Kudolo M; Anton DB; Sita G; Romasco J; Geibel C; Lämmerhofer M; Goettert MI; Tarozzi A; Laufer SA; Koch P
    Int J Mol Sci; 2020 Oct; 21(21):. PubMed ID: 33105671
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3β inhibitors.
    Lozinskaya NA; Babkov DA; Zaryanova EV; Bezsonova EN; Efremov AM; Tsymlyakov MD; Anikina LV; Zakharyascheva OY; Borisov AV; Perfilova VN; Tyurenkov IN; Proskurnina MV; Spasov AA
    Bioorg Med Chem; 2019 May; 27(9):1804-1817. PubMed ID: 30902399
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of Novel GSK-3β Inhibitors Using Pharmacophore and Virtual Screening Studies.
    Balakrishnan N; Raj JS; Kandakatla N
    Interdiscip Sci; 2016 Sep; 8(3):303-11. PubMed ID: 26298578
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.