162 related articles for article (PubMed ID: 29215700)
1. Novel smoothened antagonists as anti-neoplastic agents for the treatment of osteosarcoma.
Bernardini G; Geminiani M; Gambassi S; Orlandini M; Petricci E; Marzocchi B; Laschi M; Taddei M; Manetti F; Santucci A
J Cell Physiol; 2018 Jun; 233(6):4961-4971. PubMed ID: 29215700
[TBL] [Abstract][Full Text] [Related]
2. Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe.
Pietrobono S; Santini R; Gagliardi S; Dapporto F; Colecchia D; Chiariello M; Leone C; Valoti M; Manetti F; Petricci E; Taddei M; Stecca B
Cell Death Dis; 2018 Feb; 9(2):142. PubMed ID: 29396391
[TBL] [Abstract][Full Text] [Related]
3. Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma.
Lo WW; Wunder JS; Dickson BC; Campbell V; McGovern K; Alman BA; Andrulis IL
Cancer; 2014 Feb; 120(4):537-47. PubMed ID: 24151134
[TBL] [Abstract][Full Text] [Related]
4. Degalactotigonin, a Natural Compound from
Zhao Z; Jia Q; Wu MS; Xie X; Wang Y; Song G; Zou CY; Tang Q; Lu J; Huang G; Wang J; Lin DC; Koeffler HP; Yin JQ; Shen J
Clin Cancer Res; 2018 Jan; 24(1):130-144. PubMed ID: 28951519
[No Abstract] [Full Text] [Related]
5. Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold.
Berardozzi S; Bernardi F; Infante P; Ingallina C; Toscano S; De Paolis E; Alfonsi R; Caimano M; Botta B; Mori M; Di Marcotullio L; Ghirga F
Eur J Med Chem; 2018 Aug; 156():554-562. PubMed ID: 30025349
[TBL] [Abstract][Full Text] [Related]
6. Novel Acylguanidine Derivatives Targeting Smoothened Induce Antiproliferative and Pro-Apoptotic Effects in Chronic Myeloid Leukemia Cells.
Chiarenza A; Manetti F; Petricci E; Ruat M; Naldini A; Taddei M; Carraro F
PLoS One; 2016; 11(3):e0149919. PubMed ID: 26934052
[TBL] [Abstract][Full Text] [Related]
7. Honokiol suppresses proliferation and induces apoptosis via regulation of the miR‑21/PTEN/PI3K/AKT signaling pathway in human osteosarcoma cells.
Yang J; Zou Y; Jiang D
Int J Mol Med; 2018 Apr; 41(4):1845-1854. PubMed ID: 29393336
[TBL] [Abstract][Full Text] [Related]
8. Molecular Modelling of Berberine Derivatives as Inhibitors of Human Smoothened Receptor and Hedgehog Signalling Pathway Using a Newly Developed Algorithm on Anti-Cancer Drugs.
Kaboli PJ; Bazrafkan M; Ismail P; Ling KH
Recent Pat Anticancer Drug Discov; 2017 Nov; 12(4):384-400. PubMed ID: 28969581
[TBL] [Abstract][Full Text] [Related]
9. Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity.
Solinas A; Faure H; Roudaut H; Traiffort E; Schoenfelder A; Mann A; Manetti F; Taddei M; Ruat M
J Med Chem; 2012 Feb; 55(4):1559-71. PubMed ID: 22268551
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of Gli leads to antitumor growth and enhancement of cisplatin-induced cytotoxicity in large cell neuroendocrine carcinoma of the lung.
Ishiwata T; Iwasawa S; Ebata T; Fan M; Tada Y; Tatsumi K; Takiguchi Y
Oncol Rep; 2018 Mar; 39(3):1148-1154. PubMed ID: 29328464
[TBL] [Abstract][Full Text] [Related]
11. S-adenosylmethionine blocks osteosarcoma cells proliferation and invasion in vitro and tumor metastasis in vivo: therapeutic and diagnostic clinical applications.
Parashar S; Cheishvili D; Arakelian A; Hussain Z; Tanvir I; Khan HA; Szyf M; Rabbani SA
Cancer Med; 2015 May; 4(5):732-44. PubMed ID: 25619880
[TBL] [Abstract][Full Text] [Related]
12. The Role of Smoothened in Cancer.
Jeng KS; Sheen IS; Leu CM; Tseng PH; Chang CF
Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32962123
[TBL] [Abstract][Full Text] [Related]
13. Let-7d miRNA Shows Both Antioncogenic and Oncogenic Functions in Osteosarcoma-Derived 3AB-OS Cancer Stem Cells.
Di Fiore R; Drago-Ferrante R; Pentimalli F; Di Marzo D; Forte IM; Carlisi D; De Blasio A; Tesoriere G; Giordano A; Vento R
J Cell Physiol; 2016 Aug; 231(8):1832-41. PubMed ID: 26679758
[TBL] [Abstract][Full Text] [Related]
14. The Anthelmintic Drug Niclosamide Inhibits the Proliferative Activity of Human Osteosarcoma Cells by Targeting Multiple Signal Pathways.
Liao Z; Nan G; Yan Z; Zeng L; Deng Y; Ye J; Zhang Z; Qiao M; Li R; Denduluri S; Wang J; Wei Q; Geng N; Zhao L; Lu S; Wang X; Zhou G; Luu HH; Haydon RC; He TC; Wang Z
Curr Cancer Drug Targets; 2015; 15(8):726-38. PubMed ID: 26118906
[TBL] [Abstract][Full Text] [Related]
15. STAT3 inhibitor, cucurbitacin I, is a novel therapeutic agent for osteosarcoma.
Oi T; Asanuma K; Matsumine A; Matsubara T; Nakamura T; Iino T; Asanuma Y; Goto M; Okuno K; Kakimoto T; Yada Y; Sudo A
Int J Oncol; 2016 Dec; 49(6):2275-2284. PubMed ID: 27840900
[TBL] [Abstract][Full Text] [Related]
16. Single-walled carbon nanotube: One specific inhibitor of cancer stem cells in osteosarcoma upon downregulation of the TGFβ1 signaling.
Miao Y; Zhang H; Pan Y; Ren J; Ye M; Xia F; Huang R; Lin Z; Jiang S; Zhang Y; Songyang Z; Zhang Y
Biomaterials; 2017 Dec; 149():29-40. PubMed ID: 28988062
[TBL] [Abstract][Full Text] [Related]
17. A New Smoothened Antagonist Bearing the Purine Scaffold Shows Antitumour Activity In Vitro and In Vivo.
Zárate AM; Espinosa-Bustos C; Guerrero S; Fierro A; Oyarzún-Ampuero F; Quest AFG; Di Marcotullio L; Loricchio E; Caimano M; Calcaterra A; González-Quiroz M; Aguirre A; Meléndez J; Salas CO
Int J Mol Sci; 2021 Aug; 22(16):. PubMed ID: 34445078
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of nuclear factor-κB by dehydroxymethylepoxyquinomicin induces schedule-dependent chemosensitivity to anticancer drugs and enhances chemoinduced apoptosis in osteosarcoma cells.
Castro-Gamero AM; Borges KS; da Silva Silveira V; Lira RC; de Paula Gomes Queiroz R; Valera FC; Scrideli CA; Umezawa K; Tone LG
Anticancer Drugs; 2012 Jul; 23(6):638-50. PubMed ID: 22382389
[TBL] [Abstract][Full Text] [Related]
19. MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.
Hoch L; Faure H; Roudaut H; Schoenfelder A; Mann A; Girard N; Bihannic L; Ayrault O; Petricci E; Taddei M; Rognan D; Ruat M
FASEB J; 2015 May; 29(5):1817-29. PubMed ID: 25636740
[TBL] [Abstract][Full Text] [Related]
20. Evaluation of canonical Hedgehog signaling pathway inhibition in canine osteosarcoma.
Baldanza VE; Rogic A; Yan W; Levine CB; Levine RA; Miller AD; McCleary-Wheeler AL
PLoS One; 2020; 15(4):e0231762. PubMed ID: 32348319
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]