BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 29221145)

  • 1. Subependymal giant cell astrocytomas in Tuberous Sclerosis Complex have consistent
    Bongaarts A; Giannikou K; Reinten RJ; Anink JJ; Mills JD; Jansen FE; Spliet GMW; den Dunnen WFA; Coras R; Blümcke I; Paulus W; Scholl T; Feucht M; Kotulska K; Jozwiak S; Buccoliero AM; Caporalini C; Giordano F; Genitori L; Söylemezoğlu F; Pimentel J; Nellist M; Schouten-van Meeteren AYN; Nag A; Mühlebner A; Kwiatkowski DJ; Aronica E
    Oncotarget; 2017 Nov; 8(56):95516-95529. PubMed ID: 29221145
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Subependymal giant cell astrocytomas are characterized by mTORC1 hyperactivation, a very low somatic mutation rate, and a unique gene expression profile.
    Giannikou K; Zhu Z; Kim J; Winden KD; Tyburczy ME; Marron D; Parker JS; Hebert Z; Bongaarts A; Taing L; Long HW; Pisano WV; Alexandrescu S; Godlewski B; Nellist M; Kotulska K; Jozwiak S; Roszkowski M; Mandera M; Thiele EA; Lidov H; Getz G; Devinsky O; Lawrence MS; Ligon KL; Ellison DW; Sahin M; Aronica E; Meredith DM; Kwiatkowski DJ
    Mod Pathol; 2021 Feb; 34(2):264-279. PubMed ID: 33051600
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: biallelic inactivation of TSC1 or TSC2 leads to mTOR activation.
    Chan JA; Zhang H; Roberts PS; Jozwiak S; Wieslawa G; Lewin-Kowalik J; Kotulska K; Kwiatkowski DJ
    J Neuropathol Exp Neurol; 2004 Dec; 63(12):1236-42. PubMed ID: 15624760
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of TSC1 or TSC2 mutation limited to the tumor in three cases of solitary subependymal giant cell astrocytoma using next-generation sequencing technology.
    Fohlen M; Harzallah I; Polivka M; Giuliano F; Pons L; Streichenberger N; Dorfmüller G; Touraine R
    Childs Nerv Syst; 2020 May; 36(5):961-965. PubMed ID: 32103336
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TSC2 somatic mosaic mutation, including extra-tumor tissue, may be the developmental cause of solitary subependymal giant cell astrocytoma.
    Sasaki T; Uda T; Kuki I; Kunihiro N; Okazaki S; Niida Y; Goto T
    Childs Nerv Syst; 2022 Jan; 38(1):77-83. PubMed ID: 34741623
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Subependymal Giant Cell Astrocytoma with Tuberous Sclerosis Complex(TSC-SEGA)].
    Ichikawa T; Niida Y
    No Shinkei Geka; 2022 Jan; 50(1):111-121. PubMed ID: 35169091
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The coding and non-coding transcriptional landscape of subependymal giant cell astrocytomas.
    Bongaarts A; van Scheppingen J; Korotkov A; Mijnsbergen C; Anink JJ; Jansen FE; Spliet WGM; den Dunnen WFA; Gruber VE; Scholl T; Samueli S; Hainfellner JA; Feucht M; Kotulska K; Jozwiak S; Grajkowska W; Buccoliero AM; Caporalini C; Giordano F; Genitori L; Coras R; Blümcke I; Krsek P; Zamecnik J; Meijer L; Scicluna BP; Schouten-van Meeteren AYN; Mühlebner A; Mills JD; Aronica E
    Brain; 2020 Jan; 143(1):131-149. PubMed ID: 31834371
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biallelic TSC gene inactivation in tuberous sclerosis complex.
    Crino PB; Aronica E; Baltuch G; Nathanson KL
    Neurology; 2010 May; 74(21):1716-23. PubMed ID: 20498439
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Subependymal giant-cell astrocytomas in the absence of tuberous sclerosis.
    Reynolds RA; Aum DJ; Gonzalez-Gomez I; Wong M; Roberts K; Dahiya S; Rodriguez LF; Roland JL; Smyth MD
    J Neurosurg Pediatr; 2023 Sep; 32(3):351-357. PubMed ID: 37327147
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tuberin and hamartin expression is reduced in the majority of subependymal giant cell astrocytomas in tuberous sclerosis complex consistent with a two-hit model of pathogenesis.
    Jóźwiak S; Kwiatkowski D; Kotulska K; Larysz-Brysz M; Lewin-Kowalik J; Grajkowska W; Roszkowski M
    J Child Neurol; 2004 Feb; 19(2):102-6. PubMed ID: 15072102
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacological treatment strategies for subependymal giant cell astrocytoma (SEGA).
    Ebrahimi-Fakhari D; Franz DN
    Expert Opin Pharmacother; 2020 Aug; 21(11):1329-1336. PubMed ID: 32338549
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development.
    Giannikou K; Malinowska IA; Pugh TJ; Yan R; Tseng YY; Oh C; Kim J; Tyburczy ME; Chekaluk Y; Liu Y; Alesi N; Finlay GA; Wu CL; Signoretti S; Meyerson M; Getz G; Boehm JS; Henske EP; Kwiatkowski DJ
    PLoS Genet; 2016 Aug; 12(8):e1006242. PubMed ID: 27494029
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Distinct DNA Methylation Patterns of Subependymal Giant Cell Astrocytomas in Tuberous Sclerosis Complex.
    Bongaarts A; Mijnsbergen C; Anink JJ; Jansen FE; Spliet WGM; den Dunnen WFA; Coras R; Blümcke I; Paulus W; Gruber VE; Scholl T; Hainfellner JA; Feucht M; Kotulska K; Jozwiak S; Grajkowska W; Buccoliero AM; Caporalini C; Giordano F; Genitori L; Söylemezoğlu F; Pimentel J; Jones DTW; Scicluna BP; Schouten-van Meeteren AYN; Mühlebner A; Mills JD; Aronica E
    Cell Mol Neurobiol; 2022 Nov; 42(8):2863-2892. PubMed ID: 34709498
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficits.
    Feliciano DM; Lin TV; Hartman NW; Bartley CM; Kubera C; Hsieh L; Lafourcade C; O'Keefe RA; Bordey A
    Int J Dev Neurosci; 2013 Nov; 31(7):667-78. PubMed ID: 23485365
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Subependymal Giant Cell Astrocytomas in Tuberous Sclerosis Complex-Current Views on Their Pathogenesis and Management.
    Gao C; Zabielska B; Jiao F; Mei D; Wang X; Kotulska K; Jozwiak S
    J Clin Med; 2023 Jan; 12(3):. PubMed ID: 36769603
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A case of solitary subependymal giant cell astrocytoma with histopathological anaplasia and TSC2 gene alteration.
    Suzuki M; Kondo A; Ogino I; Akiyama O; Fujita N; Shimizu Y; Arai H
    Childs Nerv Syst; 2021 Apr; 37(4):1357-1362. PubMed ID: 32725466
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Loss of tuberin in both subependymal giant cell astrocytomas and angiomyolipomas supports a two-hit model for the pathogenesis of tuberous sclerosis tumors.
    Henske EP; Wessner LL; Golden J; Scheithauer BW; Vortmeyer AO; Zhuang Z; Klein-Szanto AJ; Kwiatkowski DJ; Yeung RS
    Am J Pathol; 1997 Dec; 151(6):1639-47. PubMed ID: 9403714
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regression of subependymal giant cell astrocytomas with RAD001 (Everolimus) in tuberous sclerosis complex.
    Yalon M; Ben-Sira L; Constantini S; Toren A
    Childs Nerv Syst; 2011 Jan; 27(1):179-81. PubMed ID: 20703486
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Characterization of a Subependymal Giant Astrocytoma-Like Cell Line from Murine Astrocyte with mTORC1 Hyperactivation.
    Tang X; Angst G; Haas M; Yang F; Wang C
    Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33923449
    [TBL] [Abstract][Full Text] [Related]  

  • 20. BRAF V600E mutations are frequent in dysembryoplastic neuroepithelial tumors and subependymal giant cell astrocytomas.
    Lee D; Cho YH; Kang SY; Yoon N; Sung CO; Suh YL
    J Surg Oncol; 2015 Mar; 111(3):359-64. PubMed ID: 25346165
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.