BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

286 related articles for article (PubMed ID: 29223097)

  • 41. Taxol and discodermolide represent a synergistic drug combination in human carcinoma cell lines.
    Martello LA; McDaid HM; Regl DL; Yang CP; Meng D; Pettus TR; Kaufman MD; Arimoto H; Danishefsky SJ; Smith AB; Horwitz SB
    Clin Cancer Res; 2000 May; 6(5):1978-87. PubMed ID: 10815923
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Identification and biological activities of new taccalonolide microtubule stabilizers.
    Peng J; Risinger AL; Fest GA; Jackson EM; Helms G; Polin LA; Mooberry SL
    J Med Chem; 2011 Sep; 54(17):6117-24. PubMed ID: 21800839
    [TBL] [Abstract][Full Text] [Related]  

  • 43. The solid state, solution and tubulin-bound conformations of agents that promote microtubule stabilization.
    Jiménez-Barbero J; Amat-Guerri F; Snyder JP
    Curr Med Chem Anticancer Agents; 2002 Jan; 2(1):91-122. PubMed ID: 12678753
    [TBL] [Abstract][Full Text] [Related]  

  • 44. From Natural Products to Designer Drugs: Development and Molecular Mechanisms Action of Novel Anti-Microtubule Breast Cancer Therapeutics.
    Mahaddalkar T; Lopus M
    Curr Top Med Chem; 2017; 17(22):2559-2568. PubMed ID: 28056739
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Anticancer therapy with novel tubulin-interacting drugs.
    Kavallaris M; Verrills NM; Hill BT
    Drug Resist Updat; 2001 Dec; 4(6):392-401. PubMed ID: 12030786
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Structure-activity profiles of eleutherobin analogs and their cross-resistance in Taxol-resistant cell lines.
    McDaid HM; Bhattacharya SK; Chen XT; He L; Shen HJ; Gutteridge CE; Horwitz SB; Danishefsky SJ
    Cancer Chemother Pharmacol; 1999; 44(2):131-7. PubMed ID: 10412947
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Synthesis and SAR requirements of adamantane-colchicine conjugates with both microtubule depolymerizing and tubulin clustering activities.
    Zefirova ON; Nurieva EV; Shishov DV; Baskin II; Fuchs F; Lemcke H; Schröder F; Weiss DG; Zefirov NS; Kuznetsov SA
    Bioorg Med Chem; 2011 Sep; 19(18):5529-38. PubMed ID: 21873068
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Induction of accelerated senescence by the microtubule-stabilizing agent peloruside A.
    Chan A; Gilfillan C; Templeton N; Paterson I; Northcote PT; Miller JH
    Invest New Drugs; 2017 Dec; 35(6):706-717. PubMed ID: 28733703
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Tubulin-interactive natural products as anticancer agents.
    Kingston DG
    J Nat Prod; 2009 Mar; 72(3):507-15. PubMed ID: 19125622
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Synthesis and high content cell-based profiling of simplified analogues of the microtubule stabilizer (+)-discodermolide.
    Minguez JM; Giuliano KA; Balachandran R; Madiraju C; Curran DP; Day BW
    Mol Cancer Ther; 2002 Dec; 1(14):1305-13. PubMed ID: 12516963
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Sagopilone (ZK-EPO): from a natural product to a fully synthetic clinical development candidate.
    Klar U; Hoffmann J; Giurescu M
    Expert Opin Investig Drugs; 2008 Nov; 17(11):1735-48. PubMed ID: 18922109
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Toward Discovery of Novel Microtubule Targeting Agents: A SNAP-tag-Based High-Content Screening Assay for the Analysis of Microtubule Dynamics and Cell Cycle Progression.
    Berges N; Arens K; Kreusch V; Fischer R; Di Fiore S
    SLAS Discov; 2017 Apr; 22(4):387-398. PubMed ID: 28328318
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Ceratamines, structurally simple microtubule-stabilizing antimitotic agents with unusual cellular effects.
    Karjala G; Chan Q; Manzo E; Andersen RJ; Roberge M
    Cancer Res; 2005 Apr; 65(8):3040-3. PubMed ID: 15833830
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Peloruside A synergizes with other microtubule stabilizing agents in cultured cancer cell lines.
    Wilmes A; Bargh K; Kelly C; Northcote PT; Miller JH
    Mol Pharm; 2007; 4(2):269-80. PubMed ID: 17397239
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Epothilones: a novel class of microtubule-stabilizing drugs for the treatment of cancer.
    Trivedi M; Budihardjo I; Loureiro K; Reid TR; Ma JD
    Future Oncol; 2008 Aug; 4(4):483-500. PubMed ID: 18684060
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Desoxyepothilone B: an efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B.
    Chou TC; Zhang XG; Balog A; Su DS; Meng D; Savin K; Bertino JR; Danishefsky SJ
    Proc Natl Acad Sci U S A; 1998 Aug; 95(16):9642-7. PubMed ID: 9689134
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Relationship between the structures of taxane derivatives and their microtubule polymerization activity.
    Hidaka M; Koga T; Kiyota H; Horiguchi T; Shi QW; Hirose K; Uchida T
    Biosci Biotechnol Biochem; 2012; 76(2):349-52. PubMed ID: 22313785
    [TBL] [Abstract][Full Text] [Related]  

  • 58. The bat flower: a source of microtubule-destabilizing and -stabilizing compounds with synergistic antiproliferative actions.
    Risinger AL; Peng J; Rohena CC; Aguilar HR; Frantz DE; Mooberry SL
    J Nat Prod; 2013 Oct; 76(10):1923-9. PubMed ID: 24087857
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Peloruside A: a lead non-taxoid-site microtubule-stabilizing agent with potential activity against cancer, neurodegeneration, and autoimmune disease.
    Kanakkanthara A; Northcote PT; Miller JH
    Nat Prod Rep; 2016 Apr; 33(4):549-61. PubMed ID: 26867978
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Diversity through semisynthesis: the chemistry and biological activity of semisynthetic epothilone derivatives.
    Altmann KH; Gaugaz FZ; Schiess R
    Mol Divers; 2011 May; 15(2):383-99. PubMed ID: 21197573
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.