141 related articles for article (PubMed ID: 29226625)
1. Identification of an antibody-based immunoassay for measuring direct target binding of RIPK1 inhibitors in cells and tissues.
Finger JN; Brusq JM; Campobasso N; Cook MN; Deutsch J; Haag H; Harris PA; Jenkins EL; Joglekar D; Lich JD; Maguire S; Nagilla R; Rivera EJ; Sun H; Votta BJ; Bertin J; Gough PJ
Pharmacol Res Perspect; 2017 Dec; 5(6):. PubMed ID: 29226625
[TBL] [Abstract][Full Text] [Related]
2. Randomized clinical study of safety, pharmacokinetics, and pharmacodynamics of RIPK1 inhibitor GSK2982772 in healthy volunteers.
Weisel K; Scott NE; Tompson DJ; Votta BJ; Madhavan S; Povey K; Wolstenholme A; Simeoni M; Rudo T; Richards-Peterson L; Sahota T; Wang JG; Lich J; Finger J; Verticelli A; Reilly M; Gough PJ; Harris PA; Bertin J; Wang ML
Pharmacol Res Perspect; 2017 Dec; 5(6):. PubMed ID: 29226626
[TBL] [Abstract][Full Text] [Related]
3. Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis.
Le Cann F; Delehouzé C; Leverrier-Penna S; Filliol A; Comte A; Delalande O; Desban N; Baratte B; Gallais I; Piquet-Pellorce C; Faurez F; Bonnet M; Mettey Y; Goekjian P; Samson M; Vandenabeele P; Bach S; Dimanche-Boitrel MT
FEBS J; 2017 Sep; 284(18):3050-3068. PubMed ID: 28715128
[TBL] [Abstract][Full Text] [Related]
4. DNA-Encoded Library Screening Identifies Benzo[b][1,4]oxazepin-4-ones as Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitors.
Harris PA; King BW; Bandyopadhyay D; Berger SB; Campobasso N; Capriotti CA; Cox JA; Dare L; Dong X; Finger JN; Grady LC; Hoffman SJ; Jeong JU; Kang J; Kasparcova V; Lakdawala AS; Lehr R; McNulty DE; Nagilla R; Ouellette MT; Pao CS; Rendina AR; Schaeffer MC; Summerfield JD; Swift BA; Totoritis RD; Ward P; Zhang A; Zhang D; Marquis RW; Bertin J; Gough PJ
J Med Chem; 2016 Mar; 59(5):2163-78. PubMed ID: 26854747
[TBL] [Abstract][Full Text] [Related]
5. Discovery of novel biaryl benzoxazepinones as dual-mode receptor-interacting protein kinase-1 (RIPK1) inhibitors.
Xin Y; Dai P; Shao H; Zhuang C; Li J
Bioorg Med Chem; 2024 Feb; 100():117611. PubMed ID: 38309200
[TBL] [Abstract][Full Text] [Related]
6. The Bcr-Abl inhibitor GNF-7 inhibits necroptosis and ameliorates acute kidney injury by targeting RIPK1 and RIPK3 kinases.
Qin X; Hu L; Shi SN; Chen X; Zhuang C; Zhang W; Jitkaew S; Pang X; Yu J; Tan YX; Wang HY; Cai Z
Biochem Pharmacol; 2020 Jul; 177():113947. PubMed ID: 32247850
[TBL] [Abstract][Full Text] [Related]
7. 6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury.
Delehouzé C; Leverrier-Penna S; Le Cann F; Comte A; Jacquard-Fevai M; Delalande O; Desban N; Baratte B; Gallais I; Faurez F; Bonnet MC; Hauteville M; Goekjian PG; Thuillier R; Favreau F; Vandenabeele P; Hauet T; Dimanche-Boitrel MT; Bach S
Sci Rep; 2017 Oct; 7(1):12931. PubMed ID: 29018243
[TBL] [Abstract][Full Text] [Related]
8. CETSA quantitatively verifies in vivo target engagement of novel RIPK1 inhibitors in various biospecimens.
Ishii T; Okai T; Iwatani-Yoshihara M; Mochizuki M; Unno S; Kuno M; Yoshikawa M; Shibata S; Nakakariya M; Yogo T; Kawamoto T
Sci Rep; 2017 Oct; 7(1):13000. PubMed ID: 29026104
[TBL] [Abstract][Full Text] [Related]
9. Identification of 5-(2,3-Dihydro-1 H-indol-5-yl)-7 H-pyrrolo[2,3- d]pyrimidin-4-amine Derivatives as a New Class of Receptor-Interacting Protein Kinase 1 (RIPK1) Inhibitors, Which Showed Potent Activity in a Tumor Metastasis Model.
Li Y; Xiong Y; Zhang G; Zhang L; Yang W; Yang J; Huang L; Qiao Z; Miao Z; Lin G; Sun Q; Niu T; Chen L; Niu D; Li L; Yang S
J Med Chem; 2018 Dec; 61(24):11398-11414. PubMed ID: 30480444
[TBL] [Abstract][Full Text] [Related]
10. RIPK1 inhibitor ameliorates colitis by directly maintaining intestinal barrier homeostasis and regulating following IECs-immuno crosstalk.
Lu H; Li H; Fan C; Qi Q; Yan Y; Wu Y; Feng C; Wu B; Gao Y; Zuo J; Tang W
Biochem Pharmacol; 2020 Feb; 172():113751. PubMed ID: 31837309
[TBL] [Abstract][Full Text] [Related]
11. Structure guided design of potent and selective ponatinib-based hybrid inhibitors for RIPK1.
Najjar M; Suebsuwong C; Ray SS; Thapa RJ; Maki JL; Nogusa S; Shah S; Saleh D; Gough PJ; Bertin J; Yuan J; Balachandran S; Cuny GD; Degterev A
Cell Rep; 2015 Mar; 10(11):1850-60. PubMed ID: 25801024
[TBL] [Abstract][Full Text] [Related]
12. Receptor-interacting protein kinase 1 (RIPK1) as a therapeutic target.
Mifflin L; Ofengeim D; Yuan J
Nat Rev Drug Discov; 2020 Aug; 19(8):553-571. PubMed ID: 32669658
[TBL] [Abstract][Full Text] [Related]
13. MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death.
Dondelinger Y; Delanghe T; Rojas-Rivera D; Priem D; Delvaeye T; Bruggeman I; Van Herreweghe F; Vandenabeele P; Bertrand MJM
Nat Cell Biol; 2017 Oct; 19(10):1237-1247. PubMed ID: 28920952
[TBL] [Abstract][Full Text] [Related]
14. RIPK1 inhibitor Cpd-71 attenuates renal dysfunction in cisplatin-treated mice via attenuating necroptosis, inflammation and oxidative stress.
Wang JN; Liu MM; Wang F; Wei B; Yang Q; Cai YT; Chen X; Liu XQ; Jiang L; Li C; Hu XW; Yu JT; Ma TT; Jin J; Wu YG; Li J; Meng XM
Clin Sci (Lond); 2019 Jul; 133(14):1609-1627. PubMed ID: 31315969
[TBL] [Abstract][Full Text] [Related]
15. Genetic Inhibition of Receptor Interacting Protein Kinase-1 Reduces Cell Death and Improves Functional Outcome After Intracerebral Hemorrhage in Mice.
Lule S; Wu L; McAllister LM; Edmiston WJ; Chung JY; Levy E; Zheng Y; Gough PJ; Bertin J; Degterev A; Lo EH; Whalen MJ
Stroke; 2017 Sep; 48(9):2549-2556. PubMed ID: 28765287
[TBL] [Abstract][Full Text] [Related]
16. RIPK1 Binds MCU to Mediate Induction of Mitochondrial Ca
Zeng F; Chen X; Cui W; Wen W; Lu F; Sun X; Ma D; Yuan Y; Li Z; Hou N; Zhao H; Bi X; Zhao J; Zhou J; Zhang Y; Xiao RP; Cai J; Zhang X
Cancer Res; 2018 Jun; 78(11):2876-2885. PubMed ID: 29531160
[TBL] [Abstract][Full Text] [Related]
17. FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.
Wang Z; Feng J; Yu J; Chen G
J Cell Sci; 2019 May; 132(10):. PubMed ID: 31028177
[TBL] [Abstract][Full Text] [Related]
18. RIPK1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved ER stress conditions.
Estornes Y; Aguileta MA; Dubuisson C; De Keyser J; Goossens V; Kersse K; Samali A; Vandenabeele P; Bertrand MJ
Cell Death Dis; 2014 Dec; 5(12):e1555. PubMed ID: 25476903
[TBL] [Abstract][Full Text] [Related]
19. Potent and selective inhibitors of receptor-interacting protein kinase 1 that lack an aromatic back pocket group.
Hamilton GL; Chen H; Deshmukh G; Eigenbrot C; Fong R; Johnson A; Kohli PB; Lupardus PJ; Liederer BM; Ramaswamy S; Wang H; Wang J; Xu Z; Zhu Y; Vucic D; Patel S
Bioorg Med Chem Lett; 2019 Jun; 29(12):1497-1501. PubMed ID: 31000154
[TBL] [Abstract][Full Text] [Related]
20. Visualization of Receptor-Interacting Protein Kinase 1 (RIPK1) by Brain Imaging with Positron Emission Tomography.
Lan Y; Bai P; Liu Y; Afshar S; Striar R; Rattray AK; Meyer TN; Langan AG; Posner AM; Shen S; Tanzi RE; Zhang C; Wang C
J Med Chem; 2021 Oct; 64(20):15420-15428. PubMed ID: 34652135
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
