141 related articles for article (PubMed ID: 29226625)
21. When PERK inhibitors turn out to be new potent RIPK1 inhibitors: critical issues on the specificity and use of GSK2606414 and GSK2656157.
Rojas-Rivera D; Delvaeye T; Roelandt R; Nerinckx W; Augustyns K; Vandenabeele P; Bertrand MJM
Cell Death Differ; 2017 Jun; 24(6):1100-1110. PubMed ID: 28452996
[TBL] [Abstract][Full Text] [Related]
22. Structure-Based Design of Novel Alkynyl Thio-Benzoxazepinone Receptor-Interacting Protein Kinase-1 Inhibitors: Extending the Chemical Space from the Allosteric to ATP Binding Pockets.
Quan D; Hou R; Shao H; Zhang X; Yu J; Zhang W; Yuan H; Zhuang C
J Med Chem; 2023 Feb; 66(4):3073-3087. PubMed ID: 36724216
[TBL] [Abstract][Full Text] [Related]
23. 24(S)-Hydroxycholesterol induces RIPK1-dependent but MLKL-independent cell death in the absence of caspase-8.
Vo DK; Urano Y; Takabe W; Saito Y; Noguchi N
Steroids; 2015 Jul; 99(Pt B):230-7. PubMed ID: 25697054
[TBL] [Abstract][Full Text] [Related]
24. Ophiopogonin D' induces RIPK1‑dependent necroptosis in androgen‑dependent LNCaP prostate cancer cells.
Lu Z; Wu C; Zhu M; Song W; Wang H; Wang J; Guo J; Li N; Liu J; Li Y; Xu H
Int J Oncol; 2020 Feb; 56(2):439-447. PubMed ID: 31894265
[TBL] [Abstract][Full Text] [Related]
25. Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases.
Harris PA; Berger SB; Jeong JU; Nagilla R; Bandyopadhyay D; Campobasso N; Capriotti CA; Cox JA; Dare L; Dong X; Eidam PM; Finger JN; Hoffman SJ; Kang J; Kasparcova V; King BW; Lehr R; Lan Y; Leister LK; Lich JD; MacDonald TT; Miller NA; Ouellette MT; Pao CS; Rahman A; Reilly MA; Rendina AR; Rivera EJ; Schaeffer MC; Sehon CA; Singhaus RR; Sun HH; Swift BA; Totoritis RD; Vossenkämper A; Ward P; Wisnoski DD; Zhang D; Marquis RW; Gough PJ; Bertin J
J Med Chem; 2017 Feb; 60(4):1247-1261. PubMed ID: 28151659
[TBL] [Abstract][Full Text] [Related]
26. Safety, pharmacokinetics and target engagement of novel RIPK1 inhibitor SAR443060 (DNL747) for neurodegenerative disorders: Randomized, placebo-controlled, double-blind phase I/Ib studies in healthy subjects and patients.
Vissers MFJM; Heuberger JAAC; Groeneveld GJ; Oude Nijhuis J; De Deyn PP; Hadi S; Harris J; Tsai RM; Cruz-Herranz A; Huang F; Tong V; Erickson R; Zhu Y; Scearce-Levie K; Hsiao-Nakamoto J; Tang X; Chang M; Fox BM; Estrada AA; Pomponio RJ; Alonso-Alonso M; Zilberstein M; Atassi N; Troyer MD; Ho C
Clin Transl Sci; 2022 Aug; 15(8):2010-2023. PubMed ID: 35649245
[TBL] [Abstract][Full Text] [Related]
27. Quantitative target engagement of RIPK1 in human whole blood via the cellular thermal shift assay for potential pre-clinical and clinical applications.
Patel S; Karlsson M; Klahn JT; Gambino F; Costa H; McGuire KA; Baumgartner CK; Williams J; Sandoz S; Kath JE
SLAS Discov; 2024 Mar; 29(2):100135. PubMed ID: 38101572
[TBL] [Abstract][Full Text] [Related]
28. RIPK1 Inhibition Enhances Pirarubicin Cytotoxic Efficacy through AKT-P21-dependent Pathway in Hepatocellular Carcinoma.
Huang H; Chen T; Zhou Y; Geng L; Shen T; Zhou L; Zheng S
Int J Med Sci; 2018; 15(14):1648-1657. PubMed ID: 30588188
[TBL] [Abstract][Full Text] [Related]
29.
Zhang H; Xu L; Qin X; Chen X; Cong H; Hu L; Chen L; Miao Z; Zhang W; Cai Z; Zhuang C
J Med Chem; 2019 Jul; 62(14):6665-6681. PubMed ID: 31095385
[TBL] [Abstract][Full Text] [Related]
30. Small-Molecule Inhibitors of Necroptosis: Current Status and Perspectives.
Zhuang C; Chen F
J Med Chem; 2020 Feb; 63(4):1490-1510. PubMed ID: 31622096
[TBL] [Abstract][Full Text] [Related]
31. A novel RIPK1 inhibitor that prevents retinal degeneration in a rat glaucoma model.
Do YJ; Sul JW; Jang KH; Kang NS; Kim YH; Kim YG; Kim E
Exp Cell Res; 2017 Oct; 359(1):30-38. PubMed ID: 28803066
[TBL] [Abstract][Full Text] [Related]
32. Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-β Synthesis Induced by Lipopolysaccharide.
Saleh D; Najjar M; Zelic M; Shah S; Nogusa S; Polykratis A; Paczosa MK; Gough PJ; Bertin J; Whalen M; Fitzgerald KA; Slavov N; Pasparakis M; Balachandran S; Kelliher M; Mecsas J; Degterev A
J Immunol; 2017 Jun; 198(11):4435-4447. PubMed ID: 28461567
[TBL] [Abstract][Full Text] [Related]
33. Identification and Characterization of NTB451 as a Potential Inhibitor of Necroptosis.
In EJ; Lee Y; Koppula S; Kim TY; Han JH; Lee KH; Kang TB
Molecules; 2018 Nov; 23(11):. PubMed ID: 30400632
[TBL] [Abstract][Full Text] [Related]
34. K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo.
Shutinoski B; Alturki NA; Rijal D; Bertin J; Gough PJ; Schlossmacher MG; Sad S
Cell Death Differ; 2016 Oct; 23(10):1628-37. PubMed ID: 27258786
[TBL] [Abstract][Full Text] [Related]
35. p38
Menon MB; Gropengießer J; Fischer J; Novikova L; Deuretzbacher A; Lafera J; Schimmeck H; Czymmeck N; Ronkina N; Kotlyarov A; Aepfelbacher M; Gaestel M; Ruckdeschel K
Nat Cell Biol; 2017 Oct; 19(10):1248-1259. PubMed ID: 28920954
[TBL] [Abstract][Full Text] [Related]
36. RIPK1 protects from TNF-α-mediated liver damage during hepatitis.
Filliol A; Piquet-Pellorce C; Le Seyec J; Farooq M; Genet V; Lucas-Clerc C; Bertin J; Gough PJ; Dimanche-Boitrel MT; Vandenabeele P; Bertrand MJ; Samson M
Cell Death Dis; 2016 Nov; 7(11):e2462. PubMed ID: 27831558
[TBL] [Abstract][Full Text] [Related]
37. Tocopherol suppresses 24(S)-hydroxycholesterol-induced cell death via inhibition of CaMKII phosphorylation.
Kimura Y; Asa M; Urano Y; Saito Y; Nishikawa K; Noguchi N
Biochimie; 2018 Oct; 153():203-209. PubMed ID: 30244813
[TBL] [Abstract][Full Text] [Related]
38. HIV-1 protease cleaves the serine-threonine kinases RIPK1 and RIPK2.
Wagner RN; Reed JC; Chanda SK
Retrovirology; 2015 Aug; 12():74. PubMed ID: 26297639
[TBL] [Abstract][Full Text] [Related]
39. Knockdown of RIPK1 Markedly Exacerbates Murine Immune-Mediated Liver Injury through Massive Apoptosis of Hepatocytes, Independent of Necroptosis and Inhibition of NF-κB.
Suda J; Dara L; Yang L; Aghajan M; Song Y; Kaplowitz N; Liu ZX
J Immunol; 2016 Oct; 197(8):3120-3129. PubMed ID: 27605011
[TBL] [Abstract][Full Text] [Related]
40. RIPK1 can function as an inhibitor rather than an initiator of RIPK3-dependent necroptosis.
Kearney CJ; Cullen SP; Clancy D; Martin SJ
FEBS J; 2014 Nov; 281(21):4921-34. PubMed ID: 25195660
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
