BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 29227281)

  • 1. Targeting Mcl-1 enhances DNA replication stress sensitivity to cancer therapy.
    Chen G; Magis AT; Xu K; Park D; Yu DS; Owonikoko TK; Sica GL; Satola SW; Ramalingam SS; Curran WJ; Doetsch PW; Deng X
    J Clin Invest; 2018 Jan; 128(1):500-516. PubMed ID: 29227281
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The pendulum of the Ku-Ku clock.
    Shibata A; Jeggo P; Löbrich M
    DNA Repair (Amst); 2018 Nov; 71():164-171. PubMed ID: 30177438
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Microhomology-mediated end joining: Good, bad and ugly.
    Seol JH; Shim EY; Lee SE
    Mutat Res; 2018 May; 809():81-87. PubMed ID: 28754468
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nuclear PTEN interferes with binding of Ku70 at double-strand breaks through post-translational poly(ADP-ribosyl)ation.
    Guan J; Zhao Q; Mao W
    Biochim Biophys Acta; 2016 Dec; 1863(12):3106-3115. PubMed ID: 27741411
    [TBL] [Abstract][Full Text] [Related]  

  • 5. KU70 Inhibition Impairs Both Non-Homologous End Joining and Homologous Recombination DNA Damage Repair Through SHP-1 Induced Dephosphorylation of SIRT1 in T-Cell Acute Lymphoblastic Leukemia (T-ALL) [corrected].
    Yu W; Li L; Wang G; Zhang W; Xu J; Liang A
    Cell Physiol Biochem; 2018; 49(6):2111-2123. PubMed ID: 30273928
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.
    Lu H; Shamanna RA; de Freitas JK; Okur M; Khadka P; Kulikowicz T; Holland PP; Tian J; Croteau DL; Davis AJ; Bohr VA
    Nat Commun; 2017 Dec; 8(1):2039. PubMed ID: 29229926
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Human T-Cell Leukemia Virus Type 1 Basic Leucine Zipper Factor Attenuates Repair of Double-Stranded DNA Breaks via Nonhomologous End Joining.
    Rushing AW; Hoang K; Polakowski N; Lemasson I
    J Virol; 2018 Aug; 92(15):. PubMed ID: 29769340
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel small molecule inhibitor of the DNA repair protein Ku70/80.
    Weterings E; Gallegos AC; Dominick LN; Cooke LS; Bartels TN; Vagner J; Matsunaga TO; Mahadevan D
    DNA Repair (Amst); 2016 Jul; 43():98-106. PubMed ID: 27130816
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Repurposing of mTOR Complex Inhibitors Attenuates MCL-1 and Sensitizes to PARP Inhibition.
    Mattoo AR; Joun A; Jessup JM
    Mol Cancer Res; 2019 Jan; 17(1):42-53. PubMed ID: 30201826
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphorylation of Ku dictates DNA double-strand break (DSB) repair pathway choice in S phase.
    Lee KJ; Saha J; Sun J; Fattah KR; Wang SC; Jakob B; Chi L; Wang SY; Taucher-Scholz G; Davis AJ; Chen DJ
    Nucleic Acids Res; 2016 Feb; 44(4):1732-45. PubMed ID: 26712563
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cyclin-dependent kinase-dependent phosphorylation of Lif1 and Sae2 controls imprecise nonhomologous end joining accompanied by double-strand break resection.
    Matsuzaki K; Terasawa M; Iwasaki D; Higashide M; Shinohara M
    Genes Cells; 2012 Jun; 17(6):473-93. PubMed ID: 22563681
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ku DNA End-Binding Activity Promotes Repair Fidelity and Influences End-Processing During Nonhomologous End-Joining in
    Emerson CH; Lopez CR; Ribes-Zamora A; Polleys EJ; Williams CL; Yeo L; Zaneveld JE; Chen R; Bertuch AA
    Genetics; 2018 May; 209(1):115-128. PubMed ID: 29500182
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Common and unique genetic interactions of the poly(ADP-ribose) polymerases PARP1 and PARP2 with DNA double-strand break repair pathways.
    Ghosh R; Roy S; Kamyab J; Danzter F; Franco S
    DNA Repair (Amst); 2016 Sep; 45():56-62. PubMed ID: 27373144
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination.
    Zan H; Tat C; Qiu Z; Taylor JR; Guerrero JA; Shen T; Casali P
    Nat Commun; 2017 Feb; 8():14244. PubMed ID: 28176781
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MCL-1 Depletion Impairs DNA Double-Strand Break Repair and Reinitiation of Stalled DNA Replication Forks.
    Mattoo AR; Pandita RK; Chakraborty S; Charaka V; Mujoo K; Hunt CR; Pandita TK
    Mol Cell Biol; 2017 Feb; 37(3):. PubMed ID: 27821478
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of UMI-77 as a novel Ku70/80 inhibitor sensitizing cancer cells to DNA damaging agents in vitro and in vivo.
    Chen X; Chen C; Luo C; Liu J; Lin Z
    Eur J Pharmacol; 2024 Jul; 975():176647. PubMed ID: 38754534
    [TBL] [Abstract][Full Text] [Related]  

  • 17. VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair.
    van den Boom J; Wolf M; Weimann L; Schulze N; Li F; Kaschani F; Riemer A; Zierhut C; Kaiser M; Iliakis G; Funabiki H; Meyer H
    Mol Cell; 2016 Oct; 64(1):189-198. PubMed ID: 27716483
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rational combination therapy for hepatocellular carcinoma with PARP1 and DNA-PK inhibitors.
    Wang C; Tang H; Geng A; Dai B; Zhang H; Sun X; Chen Y; Qiao Z; Zhu H; Yang J; Chen J; He Q; Qin N; Xie J; Tan R; Wan X; Gao S; Jiang Y; Sun FL; Mao Z
    Proc Natl Acad Sci U S A; 2020 Oct; 117(42):26356-26365. PubMed ID: 33020270
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of homologous recombination by hyperthermia shunts early double strand break repair to non-homologous end-joining.
    Bergs JW; Krawczyk PM; Borovski T; ten Cate R; Rodermond HM; Stap J; Medema JP; Haveman J; Essers J; van Bree C; Stalpers LJ; Kanaar R; Aten JA; Franken NA
    DNA Repair (Amst); 2013 Jan; 12(1):38-45. PubMed ID: 23237939
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of nonhomologous DNA end joining, conservative homologous recombination, and single-strand annealing in the cell cycle-dependent repair of DNA double-strand breaks induced by H(2)O(2) in mammalian cells.
    Frankenberg-Schwager M; Becker M; Garg I; Pralle E; Wolf H; Frankenberg D
    Radiat Res; 2008 Dec; 170(6):784-93. PubMed ID: 19138034
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.