235 related articles for article (PubMed ID: 29227648)
1. Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure.
Dohle W; Jourdan FL; Menchon G; Prota AE; Foster PA; Mannion P; Hamel E; Thomas MP; Kasprzyk PG; Ferrandis E; Steinmetz MO; Leese MP; Potter BVL
J Med Chem; 2018 Feb; 61(3):1031-1044. PubMed ID: 29227648
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and evaluation of benzimidazole carbamates bearing indole moieties for antiproliferative and antitubulin activities.
Guan Q; Han C; Zuo D; Zhai M; Li Z; Zhang Q; Zhai Y; Jiang X; Bao K; Wu Y; Zhang W
Eur J Med Chem; 2014 Nov; 87():306-15. PubMed ID: 25262051
[TBL] [Abstract][Full Text] [Related]
3. Tetrahydroisoquinoline Sulfamates as Potent Microtubule Disruptors: Synthesis, Antiproliferative and Antitubulin Activity of Dichlorobenzyl-Based Derivatives, and a Tubulin Cocrystal Structure.
Dohle W; Prota AE; Menchon G; Hamel E; Steinmetz MO; Potter BVL
ACS Omega; 2019 Jan; 4(1):755-764. PubMed ID: 30775645
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors.
Khelifi I; Naret T; Renko D; Hamze A; Bernadat G; Bignon J; Lenoir C; Dubois J; Brion JD; Provot O; Alami M
Eur J Med Chem; 2017 Feb; 127():1025-1034. PubMed ID: 28166995
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17-O,O-bis-sulfamate.
Jourdan F; Leese MP; Dohle W; Hamel E; Ferrandis E; Newman SP; Purohit A; Reed MJ; Potter BV
J Med Chem; 2010 Apr; 53(7):2942-51. PubMed ID: 20225862
[TBL] [Abstract][Full Text] [Related]
6. Synthesis, antitubulin, and antiproliferative SAR of C3/C1-substituted tetrahydroisoquinolines.
Dohle W; Leese MP; Jourdan FL; Major MR; Bai R; Hamel E; Ferrandis E; Kasprzyk PG; Fiore A; Newman SP; Purohit A; Potter BV
ChemMedChem; 2014 Feb; 9(2):350-70. PubMed ID: 24436228
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
Romagnoli R; Baraldi PG; Pavani MG; Tabrizi MA; Preti D; Fruttarolo F; Piccagli L; Jung MK; Hamel E; Borgatti M; Gambari R
J Med Chem; 2006 Jun; 49(13):3906-15. PubMed ID: 16789746
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of 1-benzylidene-3,4-dihydronaphthalen-2-one as a new class of microtubule-targeting agents.
Liu J; Zheng CH; Ren XH; Zhou F; Li W; Zhu J; Lv JG; Zhou YJ
J Med Chem; 2012 Jun; 55(12):5720-33. PubMed ID: 22676247
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
Lai Q; Wang Y; Wang R; Lai W; Tang L; Tao Y; Liu Y; Zhang R; Huang L; Xiang H; Zeng S; Gou L; Chen H; Yao Y; Yang J
Eur J Med Chem; 2018 Aug; 156():162-179. PubMed ID: 30006162
[TBL] [Abstract][Full Text] [Related]
10. Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents.
Leese MP; Jourdan FL; Gaukroger K; Mahon MF; Newman SP; Foster PA; Stengel C; Regis-Lydi S; Ferrandis E; Di Fiore A; De Simone G; Supuran CT; Purohit A; Reed MJ; Potter BV
J Med Chem; 2008 Mar; 51(5):1295-308. PubMed ID: 18260615
[TBL] [Abstract][Full Text] [Related]
11. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
Liu YN; Wang JJ; Ji YT; Zhao GD; Tang LQ; Zhang CM; Guo XL; Liu ZP
J Med Chem; 2016 Jun; 59(11):5341-55. PubMed ID: 27172319
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, biological evaluation, and molecular docking studies of novel 1-benzene acyl-2-(1-methylindol-3-yl)-benzimidazole derivatives as potential tubulin polymerization inhibitors.
Wang YT; Qin YJ; Yang N; Zhang YL; Liu CH; Zhu HL
Eur J Med Chem; 2015 Jun; 99():125-37. PubMed ID: 26070164
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
Penthala NR; Zong H; Ketkar A; Madadi NR; Janganati V; Eoff RL; Guzman ML; Crooks PA
Eur J Med Chem; 2015 Mar; 92():212-20. PubMed ID: 25557492
[TBL] [Abstract][Full Text] [Related]
14. 4,5-Diaryl-3H-1,2-dithiole-3-thiones and related compounds as combretastatin A-4/oltipraz hybrids: Synthesis, molecular modelling and evaluation as antiproliferative agents and inhibitors of tubulin.
Wang Z; Qi H; Shen Q; Lu G; Li M; Bao K; Wu Y; Zhang W
Eur J Med Chem; 2016 Oct; 122():520-529. PubMed ID: 27428395
[TBL] [Abstract][Full Text] [Related]
15. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
Liou JP; Wu CY; Hsieh HP; Chang CY; Chen CM; Kuo CC; Chang JY
J Med Chem; 2007 Sep; 50(18):4548-52. PubMed ID: 17685504
[TBL] [Abstract][Full Text] [Related]
16. Synthesis, biological evaluation and molecular docking studies of resveratrol derivatives possessing curcumin moiety as potent antitubulin agents.
Ruan BF; Lu X; Li TT; Tang JF; Wei Y; Wang XL; Zheng SL; Yao RS; Zhu HL
Bioorg Med Chem; 2012 Jan; 20(2):1113-21. PubMed ID: 22189271
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
Romagnoli R; Baraldi PG; Carrion MD; Cara CL; Cruz-Lopez O; Preti D; Tolomeo M; Grimaudo S; Di Cristina A; Zonta N; Balzarini J; Brancale A; Sarkar T; Hamel E
Bioorg Med Chem; 2008 May; 16(10):5367-76. PubMed ID: 18440234
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents.
Galli U; Travelli C; Aprile S; Arrigoni E; Torretta S; Grosa G; Massarotti A; Sorba G; Canonico PL; Genazzani AA; Tron GC
J Med Chem; 2015 Feb; 58(3):1345-57. PubMed ID: 25584687
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
Zhou P; Liang Y; Zhang H; Jiang H; Feng K; Xu P; Wang J; Wang X; Ding K; Luo C; Liu M; Wang Y
Eur J Med Chem; 2018 Jan; 144():817-842. PubMed ID: 29306206
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluation of novel pyrano[3,2-c]carbazole derivatives as anti-tumor agents inducing apoptosis via tubulin polymerization inhibition.
Padmaja P; Koteswara Rao G; Indrasena A; Subba Reddy BV; Patel N; Shaik AB; Reddy N; Dubey PK; Bhadra MP
Org Biomol Chem; 2015 Feb; 13(5):1404-14. PubMed ID: 25467166
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]