BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 29228061)

  • 1. Structure-activity studies of Mdm2/Mdm4-binding stapled peptides comprising non-natural amino acids.
    Chee SMQ; Wongsantichon J; Siau J; Thean D; Ferrer F; Robinson RC; Lane DP; Brown CJ; Ghadessy FJ
    PLoS One; 2017; 12(12):e0189379. PubMed ID: 29228061
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX.
    Pazgier M; Liu M; Zou G; Yuan W; Li C; Li C; Li J; Monbo J; Zella D; Tarasov SG; Lu W
    Proc Natl Acad Sci U S A; 2009 Mar; 106(12):4665-70. PubMed ID: 19255450
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties.
    Partridge AW; Kaan HYK; Juang YC; Sadruddin A; Lim S; Brown CJ; Ng S; Thean D; Ferrer F; Johannes C; Yuen TY; Kannan S; Aronica P; Tan YS; Pradhan MR; Verma CS; Hochman J; Chen S; Wan H; Ha S; Sherborne B; Lane DP; Sawyer TK
    Molecules; 2019 Jun; 24(12):. PubMed ID: 31226791
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Assessing the Efficacy of Mdm2/Mdm4-Inhibiting Stapled Peptides Using Cellular Thermal Shift Assays.
    Tan BX; Brown CJ; Ferrer FJ; Yuen TY; Quah ST; Chan BH; Jansson AE; Teo HL; Nordlund P; Lane DP
    Sci Rep; 2015 Jul; 5():12116. PubMed ID: 26159518
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The MDM2 gene family.
    Mendoza M; Mandani G; Momand J
    Biomol Concepts; 2014 Mar; 5(1):9-19. PubMed ID: 25372739
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure of a stapled peptide antagonist bound to nutlin-resistant Mdm2.
    Chee SM; Wongsantichon J; Soo Tng Q; Robinson R; Joseph TL; Verma C; Lane DP; Brown CJ; Ghadessy FJ
    PLoS One; 2014; 9(8):e104914. PubMed ID: 25115702
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Designing dual inhibitors of Mdm2/MdmX: Unexpected coupling of water with gatekeeper Y100/99.
    Lee XA; Verma C; Sim AYL
    Proteins; 2017 Aug; 85(8):1493-1506. PubMed ID: 28425639
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting the MDM2/MDM4 interaction interface as a promising approach for p53 reactivation therapy.
    Pellegrino M; Mancini F; Lucà R; Coletti A; Giacchè N; Manni I; Arisi I; Florenzano F; Teveroni E; Buttarelli M; Fici L; Brandi R; Bruno T; Fanciulli M; D'Onofrio M; Piaggio G; Pellicciari R; Pontecorvi A; Marine JC; Macchiarulo A; Moretti F
    Cancer Res; 2015 Nov; 75(21):4560-72. PubMed ID: 26359458
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MDM2 and MDM4: p53 regulators as targets in anticancer therapy.
    Toledo F; Wahl GM
    Int J Biochem Cell Biol; 2007; 39(7-8):1476-82. PubMed ID: 17499002
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure of the stapled p53 peptide bound to Mdm2.
    Baek S; Kutchukian PS; Verdine GL; Huber R; Holak TA; Lee KW; Popowicz GM
    J Am Chem Soc; 2012 Jan; 134(1):103-6. PubMed ID: 22148351
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design of a novel MDM2 binding peptide based on the p53 family.
    Madhumalar A; Lee HJ; Brown CJ; Lane D; Verma C
    Cell Cycle; 2009 Sep; 8(17):2828-36. PubMed ID: 19713735
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stapled peptides with improved potency and specificity that activate p53.
    Brown CJ; Quah ST; Jong J; Goh AM; Chiam PC; Khoo KH; Choong ML; Lee MA; Yurlova L; Zolghadr K; Joseph TL; Verma CS; Lane DP
    ACS Chem Biol; 2013 Mar; 8(3):506-12. PubMed ID: 23214419
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Systematic mutational analysis of peptide inhibition of the p53-MDM2/MDMX interactions.
    Li C; Pazgier M; Li C; Yuan W; Liu M; Wei G; Lu WY; Lu W
    J Mol Biol; 2010 Apr; 398(2):200-13. PubMed ID: 20226197
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A site-directed mutagenesis study of the MdmX RING domain.
    Egorova O; Mis M; Sheng Y
    Biochem Biophys Res Commun; 2014 May; 447(4):696-701. PubMed ID: 24755078
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Further insight into substrate recognition by USP7: structural and biochemical analysis of the HdmX and Hdm2 interactions with USP7.
    Sarkari F; La Delfa A; Arrowsmith CH; Frappier L; Sheng Y; Saridakis V
    J Mol Biol; 2010 Oct; 402(5):825-37. PubMed ID: 20713061
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stapled peptides in the p53 pathway: computer simulations reveal novel interactions of the staples with the target protein.
    Joseph TL; Lane D; Verma CS
    Cell Cycle; 2010 Nov; 9(22):4560-8. PubMed ID: 21088491
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Beta-peptides with improved affinity for hDM2 and hDMX.
    Harker EA; Daniels DS; Guarracino DA; Schepartz A
    Bioorg Med Chem; 2009 Mar; 17(5):2038-46. PubMed ID: 19211253
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anatomy of Mdm2 and Mdm4 in evolution.
    Tan BX; Liew HP; Chua JS; Ghadessy FJ; Tan YS; Lane DP; Coffill CR
    J Mol Cell Biol; 2017 Feb; 9(1):3-15. PubMed ID: 28077607
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MDM4 SNP34091 (rs4245739) and its effect on breast-, colon-, lung-, and prostate cancer risk.
    Gansmo LB; Romundstad P; Birkeland E; Hveem K; Vatten L; Knappskog S; Lønning PE
    Cancer Med; 2015 Dec; 4(12):1901-7. PubMed ID: 26471763
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High levels of the p53 inhibitor MDM4 in head and neck squamous carcinomas.
    Valentin-Vega YA; Barboza JA; Chau GP; El-Naggar AK; Lozano G
    Hum Pathol; 2007 Oct; 38(10):1553-62. PubMed ID: 17651783
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.