BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 29228247)

  • 1. A Randomized, Double-Blind, Placebo- and Active Comparator-Controlled Phase I Study of Analgesic/Antihyperalgesic Properties of ASP8477, a Fatty Acid Amide Hydrolase Inhibitor, in Healthy Female Subjects.
    Schaffler K; Yassen A; Reeh P; Passier P
    Pain Med; 2018 Jun; 19(6):1206-1218. PubMed ID: 29228247
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A Phase I, Randomized, Double-Blind, Laser-Evoked Potential Study to Evaluate the Analgesic/Antihyperalgesic Effect of ASP9226, a State-Dependent N-Type Voltage-Gated Calcium Channel Inhibitor, in Healthy Male Subjects.
    Schaffler K; He W; Passier P; Tracy K; Fakhoury A; Paul J
    Pain Med; 2018 Nov; 19(11):2246-2255. PubMed ID: 29378016
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The MOBILE Study-A Phase IIa Enriched Enrollment Randomized Withdrawal Trial to Assess the Analgesic Efficacy and Safety of ASP8477, a Fatty Acid Amide Hydrolase Inhibitor, in Patients with Peripheral Neuropathic Pain.
    Bradford D; Stirling A; Ernault E; Liosatos M; Tracy K; Moseley J; Blahunka P; Smith MD
    Pain Med; 2017 Dec; 18(12):2388-2400. PubMed ID: 28383710
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Investigation of the predictive validity of laser-EPs in normal, UVB-inflamed and capsaicin-irritated skin with four analgesic compounds in healthy volunteers.
    Schaffler K; Nicolas LB; Borta A; Brand T; Reitmeir P; Roebling R; Scholpp J
    Br J Clin Pharmacol; 2017 Jul; 83(7):1424-1435. PubMed ID: 28139023
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ASP8477, a fatty acid amide hydrolase inhibitor, exerts analgesic effects in rat models of neuropathic and dysfunctional pain.
    Kiso T; Watabiki T; Sekizawa T
    Eur J Pharmacol; 2020 Aug; 881():173194. PubMed ID: 32445705
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparison of inhibition of cutaneous histamine reaction of ebastine fast-dissolving tablet (20 mg) versus desloratadine capsule (5 mg): a randomized, double-blind, double-dummy, placebo-controlled, three-period crossover study in healthy, nonatopic adults.
    Antonijoan R; García-Gea C; Puntes M; Pérez J; Esbrí R; Serra C; Fortea J; Barbanoj MJ
    Clin Ther; 2007 May; 29(5):814-822. PubMed ID: 17697901
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vitro and in vivo pharmacological characterization of ASP8477: A novel highly selective fatty acid amide hydrolase inhibitor.
    Watabiki T; Tsuji N; Kiso T; Ozawa T; Narazaki F; Kakimoto S
    Eur J Pharmacol; 2017 Nov; 815():42-48. PubMed ID: 29017758
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An oral TRPV1 antagonist attenuates laser radiant-heat-evoked potentials and pain ratings from UV(B)-inflamed and normal skin.
    Schaffler K; Reeh P; Duan WR; Best AE; Othman AA; Faltynek CR; Locke C; Nothaft W
    Br J Clin Pharmacol; 2013 Feb; 75(2):404-14. PubMed ID: 22775239
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Randomized, double-blind, placebo-controlled, dose-escalation study: Investigation of the safety, pharmacokinetics, and antihyperalgesic activity of l-4-chlorokynurenine in healthy volunteers.
    Wallace M; White A; Grako KA; Lane R; Cato AJ; Snodgrass HR
    Scand J Pain; 2017 Oct; 17():243-251. PubMed ID: 29229209
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Analgesic effects of low-dose intravenous orphenadrine in the state of capsaicin hyperalgesia. A randomised, placebo-controlled, double-blind cross-over study using laser somatosensory evoked potentials obtained from capsaicin-irritated skin in healthy volunteers.
    Schaffler K; Reitmeir P
    Arzneimittelforschung; 2004; 54(10):673-9. PubMed ID: 15553107
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
    Wininger SJ; Miller H; Minkowitz HS; Royal MA; Ang RY; Breitmeyer JB; Singla NK
    Clin Ther; 2010 Dec; 32(14):2348-69. PubMed ID: 21353105
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A single-tablet fixed-dose combination of racemic ibuprofen/paracetamol in the management of moderate to severe postoperative dental pain in adult and adolescent patients: a multicenter, two-stage, randomized, double-blind, parallel-group, placebo-controlled, factorial study.
    Mehlisch DR; Aspley S; Daniels SE; Southerden KA; Christensen KS
    Clin Ther; 2010 Jun; 32(6):1033-49. PubMed ID: 20637958
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dose-response relationship after single oral dose administrations of morphine and oxycodone using laser-evoked potentials on UVB- and capsaicin-irritated skin in healthy male subjects.
    Hoeben E; Smit JW; Upmalis D; Rusch S; Schaffler K; Reitmeir P; Mangold B
    Pain; 2012 Aug; 153(8):1648-1656. PubMed ID: 22703892
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of the new H1-antagonist ReN1869 on capsaicin-induced hyperalgesia in human skin/Human phase-I trial using somatosensory evoked potentials induced by a CO2 laser.
    Schaffler K; Seibel K; Thomsen M; Edwards M
    Arzneimittelforschung; 2004; 54(3):187-91. PubMed ID: 15112866
    [TBL] [Abstract][Full Text] [Related]  

  • 15. IMI2-PainCare-BioPain-RCT3: a randomized, double-blind, placebo-controlled, crossover, multi-center trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by electroencephalography (EEG).
    Mouraux A; Bloms-Funke P; Boesl I; Caspani O; Chapman SC; Di Stefano G; Finnerup NB; Garcia-Larrea L; Goetz M; Kostenko A; Pelz B; Pogatzki-Zahn E; Schubart K; Stouffs A; Truini A; Tracey I; Troconiz IF; Van Niel J; Vela JM; Vincent K; Vollert J; Wanigasekera V; Wittayer M; Phillips KG; Treede RD
    Trials; 2021 Jun; 22(1):404. PubMed ID: 34140041
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Efficacy of Duloxetine in Chronic Low Back Pain with a Neuropathic Component: A Randomized, Double-blind, Placebo-controlled Crossover Trial.
    Schukro RP; Oehmke MJ; Geroldinger A; Heinze G; Kress HG; Pramhas S
    Anesthesiology; 2016 Jan; 124(1):150-8. PubMed ID: 26517858
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A new fully human recombinant FSH (follitropin epsilon): two phase I randomized placebo and comparator-controlled pharmacokinetic and pharmacodynamic trials.
    Abd-Elaziz K; Duijkers I; Stöckl L; Dietrich B; Klipping C; Eckert K; Goletz S
    Hum Reprod; 2017 Aug; 32(8):1639-1647. PubMed ID: 28591833
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Analgesic Effect of Oxytocin in Humans: A Double-Blind, Placebo-Controlled Cross-Over Study Using Laser-Evoked Potentials.
    Paloyelis Y; Krahé C; Maltezos S; Williams SC; Howard MA; Fotopoulou A
    J Neuroendocrinol; 2016 Apr; 28(4):. PubMed ID: 26660859
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparison of the analgesic effects of a fixed-dose combination of orphenadrine and diclofenac (Neodolpasse) with its single active ingredients diclofenac and orphenadrine: a placebo-controlled study using laser-induced somatosensory-evoked potentials from capsaicin-induced hyperalgesic human skin.
    Schaffler K; Reitmeir P; Gschanes A; Eggenreich U
    Drugs R D; 2005; 6(4):189-99. PubMed ID: 15991879
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A randomized study to evaluate the analgesic efficacy of a single dose of the TRPV1 antagonist mavatrep in patients with osteoarthritis.
    Mayorga AJ; Flores CM; Trudeau JJ; Moyer JA; Shalayda K; Dale M; Frustaci ME; Katz N; Manitpisitkul P; Treister R; Ratcliffe S; Romano G
    Scand J Pain; 2017 Oct; 17():134-143. PubMed ID: 28850367
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.