BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

432 related articles for article (PubMed ID: 29228881)

  • 1. Unravelling novel congeners from acetyllysine mimicking ligand targeting a lysine acetyltransferase PCAF bromodomain.
    Suryanarayanan V; Singh SK
    J Biomol Struct Dyn; 2018 Dec; 36(16):4303-4319. PubMed ID: 29228881
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure based identification and biological evaluation of novel and potent inhibitors of PCAF catalytic domain.
    Suryanarayanan V; Rajavel T; Devi KP; Singh SK
    Int J Biol Macromol; 2018 Dec; 120(Pt A):823-834. PubMed ID: 30118769
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of anti-filarial leads against aspartate semialdehyde dehydrogenase of Wolbachia endosymbiont of Brugia malayi: combined molecular docking and molecular dynamics approaches.
    Amala M; Rajamanikandan S; Prabhu D; Surekha K; Jeyakanthan J
    J Biomol Struct Dyn; 2019 Feb; 37(2):394-410. PubMed ID: 29334340
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Multiple e-pharmacophore modelling pooled with high-throughput virtual screening, docking and molecular dynamics simulations to discover potential inhibitors of Plasmodium falciparum lactate dehydrogenase (PfLDH).
    Saxena S; Durgam L; Guruprasad L
    J Biomol Struct Dyn; 2019 Apr; 37(7):1783-1799. PubMed ID: 29718775
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain.
    Chaikuad A; Lang S; Brennan PE; Temperini C; Fedorov O; Hollander J; Nachane R; Abell C; Müller S; Siegal G; Knapp S
    J Med Chem; 2016 Feb; 59(4):1648-53. PubMed ID: 26731131
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Assessment of dual inhibition property of newly discovered inhibitors against PCAF and GCN5 through in silico screening, molecular dynamics simulation and DFT approach.
    Suryanarayanan V; Singh SK
    J Recept Signal Transduct Res; 2015; 35(5):370-80. PubMed ID: 25404235
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Binding mechanism of anacardic acid, carnosol and garcinol with PCAF: A comprehensive study using molecular docking and molecular dynamics simulations and binding free energy analysis.
    Jaganathan R; Kumaradhas P
    J Cell Biochem; 2023 May; 124(5):731-742. PubMed ID: 36966470
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of selective MMP-9 inhibitors through multiple e-pharmacophore, ligand-based pharmacophore, molecular docking, and density functional theory approaches.
    Jana S; Singh SK
    J Biomol Struct Dyn; 2019 Mar; 37(4):944-965. PubMed ID: 29475408
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of potential PKC inhibitors through pharmacophore designing, 3D-QSAR and molecular dynamics simulations targeting Alzheimer's disease.
    Iqbal S; Anantha Krishnan D; Gunasekaran K
    J Biomol Struct Dyn; 2018 Nov; 36(15):4029-4044. PubMed ID: 29182053
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Deciphering the binding mode and mechanistic insights of pentadecylidenemalonate (1b) as activator of histone acetyltransferase PCAF.
    Suryanarayanan V; Singh SK
    J Biomol Struct Dyn; 2019 Jun; 37(9):2296-2309. PubMed ID: 30044210
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fluorescence polarization for the evaluation of small-molecule inhibitors of PCAF BRD/Tat-AcK50 association.
    Hu P; Wang X; Zhang B; Zhang S; Wang Q; Wang Z
    ChemMedChem; 2014 May; 9(5):928-31. PubMed ID: 24474698
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Current development of CBP/p300 inhibitors in the last decade.
    He ZX; Wei BF; Zhang X; Gong YP; Ma LY; Zhao W
    Eur J Med Chem; 2021 Jan; 209():112861. PubMed ID: 33045661
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Virtual screening of small molecules databases for discovery of novel PARP-1 inhibitors: combination of in silico and in vitro studies.
    Ekhteiari Salmas R; Unlu A; Bektaş M; Yurtsever M; Mestanoglu M; Durdagi S
    J Biomol Struct Dyn; 2017 Jul; 35(9):1899-1915. PubMed ID: 27315035
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Investigation of novel ligand targeting bromodomain-containing protein 4 (BRD4) for cancer drug discovery: complete pharmacophore approach.
    Shanmugam V; Muthukrishnan S
    J Biomol Struct Dyn; 2023; 41(23):14524-14539. PubMed ID: 36841551
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibitor design against JNK1 through e-pharmacophore modeling docking and molecular dynamics simulations.
    Katari SK; Natarajan P; Swargam S; Kanipakam H; Pasala C; Umamaheswari A
    J Recept Signal Transduct Res; 2016 Dec; 36(6):558-571. PubMed ID: 26906522
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening.
    Zhang FC; Sun ZY; Liao LP; Zuo Y; Zhang D; Wang J; Chen YT; Xiao SH; Jiang H; Lu T; Xu P; Yue LY; Du DH; Zhang H; Liu CP; Luo C
    Acta Pharmacol Sin; 2020 Feb; 41(2):286-292. PubMed ID: 31253937
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor.
    Bowers EM; Yan G; Mukherjee C; Orry A; Wang L; Holbert MA; Crump NT; Hazzalin CA; Liszczak G; Yuan H; Larocca C; Saldanha SA; Abagyan R; Sun Y; Meyers DJ; Marmorstein R; Mahadevan LC; Alani RM; Cole PA
    Chem Biol; 2010 May; 17(5):471-82. PubMed ID: 20534345
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-based virtual screening toward the discovery of novel inhibitors for impeding the protein-protein interaction between HIV-1 integrase and human lens epithelium-derived growth factor (LEDGF/p75).
    Panwar U; Singh SK
    J Biomol Struct Dyn; 2018 Sep; 36(12):3199-3217. PubMed ID: 28948865
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacophore based virtual screening for identification of effective inhibitors to combat HPV 16 E6 driven cervical cancer.
    Mohan A; Krishnamoorthy S; Sabanayagam R; Schwenk G; Feng E; Ji HF; Muthusami S
    Eur J Pharmacol; 2023 Oct; 957():175961. PubMed ID: 37549730
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacophore modeling, multiple docking, and molecular dynamics studies on Wee1 kinase inhibitors.
    Hu Y; Zhou L; Zhu X; Dai D; Bao Y; Qiu Y
    J Biomol Struct Dyn; 2019 Jul; 37(10):2703-2715. PubMed ID: 30052133
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.