BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 29230965)

  • 1. Prevention of chemotherapy-induced cachexia by ACVR2B ligand blocking has different effects on heart and skeletal muscle.
    Hulmi JJ; Nissinen TA; Räsänen M; Degerman J; Lautaoja JH; Hemanthakumar KA; Backman JT; Ritvos O; Silvennoinen M; Kivelä R
    J Cachexia Sarcopenia Muscle; 2018 Apr; 9(2):417-432. PubMed ID: 29230965
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Treating cachexia using soluble ACVR2B improves survival, alters mTOR localization, and attenuates liver and spleen responses.
    Nissinen TA; Hentilä J; Penna F; Lampinen A; Lautaoja JH; Fachada V; Holopainen T; Ritvos O; Kivelä R; Hulmi JJ
    J Cachexia Sarcopenia Muscle; 2018 Jun; 9(3):514-529. PubMed ID: 29722201
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Muscle and serum metabolomes are dysregulated in colon-26 tumor-bearing mice despite amelioration of cachexia with activin receptor type 2B ligand blockade.
    Lautaoja JH; Lalowski M; Nissinen TA; Hentilä J; Shi Y; Ritvos O; Cheng S; Hulmi JJ
    Am J Physiol Endocrinol Metab; 2019 May; 316(5):E852-E865. PubMed ID: 30860875
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes.
    Nissinen TA; Degerman J; Räsänen M; Poikonen AR; Koskinen S; Mervaala E; Pasternack A; Ritvos O; Kivelä R; Hulmi JJ
    Sci Rep; 2016 Sep; 6():32695. PubMed ID: 27666826
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activin Receptor Ligand Blocking and Cancer Have Distinct Effects on Protein and Redox Homeostasis in Skeletal Muscle and Liver.
    Hentilä J; Nissinen TA; Korkmaz A; Lensu S; Silvennoinen M; Pasternack A; Ritvos O; Atalay M; Hulmi JJ
    Front Physiol; 2018; 9():1917. PubMed ID: 30713500
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acute inhibition of myostatin-family proteins preserves skeletal muscle in mouse models of cancer cachexia.
    Benny Klimek ME; Aydogdu T; Link MJ; Pons M; Koniaris LG; Zimmers TA
    Biochem Biophys Res Commun; 2010 Jan; 391(3):1548-54. PubMed ID: 20036643
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress.
    Hulmi JJ; Hentilä J; DeRuisseau KC; Oliveira BM; Papaioannou KG; Autio R; Kujala UM; Ritvos O; Kainulainen H; Korkmaz A; Atalay M
    Free Radic Biol Med; 2016 Oct; 99():308-322. PubMed ID: 27554968
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The systemic activin response to pancreatic cancer: implications for effective cancer cachexia therapy.
    Zhong X; Pons M; Poirier C; Jiang Y; Liu J; Sandusky GE; Shahda S; Nakeeb A; Schmidt CM; House MG; Ceppa EP; Zyromski NJ; Liu Y; Jiang G; Couch ME; Koniaris LG; Zimmers TA
    J Cachexia Sarcopenia Muscle; 2019 Oct; 10(5):1083-1101. PubMed ID: 31286691
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Systemic blockade of ACVR2B ligands attenuates muscle wasting in ischemic heart failure without compromising cardiac function.
    Szabó Z; Vainio L; Lin R; Swan J; Hulmi JJ; Rahtu-Korpela L; Serpi R; Laitinen M; Pasternack A; Ritvos O; Kerkelä R; Magga J
    FASEB J; 2020 Aug; 34(8):9911-9924. PubMed ID: 32427381
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy.
    Morvan F; Rondeau JM; Zou C; Minetti G; Scheufler C; Scharenberg M; Jacobi C; Brebbia P; Ritter V; Toussaint G; Koelbing C; Leber X; Schilb A; Witte F; Lehmann S; Koch E; Geisse S; Glass DJ; Lach-Trifilieff E
    Proc Natl Acad Sci U S A; 2017 Nov; 114(47):12448-12453. PubMed ID: 29109273
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs.
    Barreto R; Waning DL; Gao H; Liu Y; Zimmers TA; Bonetto A
    Oncotarget; 2016 Jul; 7(28):43442-43460. PubMed ID: 27259276
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ACVR2B antagonism as a countermeasure to multi-organ perturbations in metastatic colorectal cancer cachexia.
    Huot JR; Pin F; Narasimhan A; Novinger LJ; Keith AS; Zimmers TA; Willis MS; Bonetto A
    J Cachexia Sarcopenia Muscle; 2020 Dec; 11(6):1779-1798. PubMed ID: 33200567
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sodium nitrate co-supplementation does not exacerbate low dose metronomic doxorubicin-induced cachexia in healthy mice.
    Campelj DG; Debruin DA; Timpani CA; Hayes A; Goodman CA; Rybalka E
    Sci Rep; 2020 Sep; 10(1):15044. PubMed ID: 32973229
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Treatment with Soluble Activin Receptor Type IIB Alters Metabolic Response in Chemotherapy-Induced Cachexia.
    O'Connell TM; Pin F; Couch ME; Bonetto A
    Cancers (Basel); 2019 Aug; 11(9):. PubMed ID: 31438622
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sex specificity of pancreatic cancer cachexia phenotypes, mechanisms, and treatment in mice and humans: role of Activin.
    Zhong X; Narasimhan A; Silverman LM; Young AR; Shahda S; Liu S; Wan J; Liu Y; Koniaris LG; Zimmers TA
    J Cachexia Sarcopenia Muscle; 2022 Aug; 13(4):2146-2161. PubMed ID: 35510530
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Systemic Blockade of ACVR2B Ligands Protects Myocardium from Acute Ischemia-Reperfusion Injury.
    Magga J; Vainio L; Kilpiö T; Hulmi JJ; Taponen S; Lin R; Räsänen M; Szabó Z; Gao E; Rahtu-Korpela L; Alakoski T; Ulvila J; Laitinen M; Pasternack A; Koch WJ; Alitalo K; Kivelä R; Ritvos O; Kerkelä R
    Mol Ther; 2019 Mar; 27(3):600-610. PubMed ID: 30765322
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ActRII blockade protects mice from cancer cachexia and prolongs survival in the presence of anti-cancer treatments.
    Hatakeyama S; Summermatter S; Jourdain M; Melly S; Minetti GC; Lach-Trifilieff E
    Skelet Muscle; 2016; 6():26. PubMed ID: 27462398
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Exogenous GDF11 induces cardiac and skeletal muscle dysfunction and wasting.
    Zimmers TA; Jiang Y; Wang M; Liang TW; Rupert JE; Au ED; Marino FE; Couch ME; Koniaris LG
    Basic Res Cardiol; 2017 Jul; 112(4):48. PubMed ID: 28647906
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Muscle NAD
    Hulmi JJ; Penna F; Pöllänen N; Nissinen TA; Hentilä J; Euro L; Lautaoja JH; Ballarò R; Soliymani R; Baumann M; Ritvos O; Pirinen E; Lalowski M
    Mol Metab; 2020 Nov; 41():101046. PubMed ID: 32599075
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ACVR2B/Fc counteracts chemotherapy-induced loss of muscle and bone mass.
    Barreto R; Kitase Y; Matsumoto T; Pin F; Colston KC; Couch KE; O'Connell TM; Couch ME; Bonewald LF; Bonetto A
    Sci Rep; 2017 Oct; 7(1):14470. PubMed ID: 29089584
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.