These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 29236027)

  • 1. Simvastatin Inhibits Cell Proliferation and Migration in Human Anaplastic Thyroid Cancer.
    Chen MC; Tsai YC; Tseng JH; Liou JJ; Horng S; Wen HC; Fan YC; Zhong WB; Hsu SP
    Int J Mol Sci; 2017 Dec; 18(12):. PubMed ID: 29236027
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lovastatin inhibits proliferation of anaplastic thyroid cancer cells through up-regulation of p27 by interfering with the Rho/ROCK-mediated pathway.
    Zhong WB; Hsu SP; Ho PY; Liang YC; Chang TC; Lee WS
    Biochem Pharmacol; 2011 Dec; 82(11):1663-72. PubMed ID: 21907187
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Involvement of cysteine-rich protein 61 in the epidermal growth factor-induced migration of human anaplastic thyroid cancer cells.
    Chin LH; Hsu SP; Zhong WB; Liang YC
    Mol Carcinog; 2016 May; 55(5):622-32. PubMed ID: 25773758
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Simvastatin-induced cell cycle arrest through inhibition of STAT3/SKP2 axis and activation of AMPK to promote p27 and p21 accumulation in hepatocellular carcinoma cells.
    Wang ST; Ho HJ; Lin JT; Shieh JJ; Wu CY
    Cell Death Dis; 2017 Feb; 8(2):e2626. PubMed ID: 28230855
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation.
    Al-Haidari AA; Syk I; Thorlacius H
    Biochem Biophys Res Commun; 2014 Mar; 446(1):68-72. PubMed ID: 24582560
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Synergistic Anti-Cancer Effect of Troglitazone and Lovastatin in a Human Anaplastic Thyroid Cancer Cell Line and in a Mouse Xenograft Model.
    Zhong WB; Tsai YC; Chin LH; Tseng JH; Tang LW; Horng S; Fan YC; Hsu SP
    Int J Mol Sci; 2018 Jun; 19(7):. PubMed ID: 29932104
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Combined treatment with troglitazone and lovastatin inhibited epidermal growth factor-induced migration through the downregulation of cysteine-rich protein 61 in human anaplastic thyroid cancer cells.
    Chin LH; Hsu SP; Zhong WB; Liang YC
    PLoS One; 2015; 10(3):e0118674. PubMed ID: 25742642
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of the RhoA/Rho-associated, coiled-coil-containing protein kinase-1 pathway is involved in the therapeutic effects of simvastatin on pulmonary arterial hypertension.
    Liu WH; Xu XH; Luo Q; Zhang HL; Wang Y; Xi QY; Zhao ZH; Liu ZH
    Clin Exp Hypertens; 2018; 40(3):224-230. PubMed ID: 29319354
    [TBL] [Abstract][Full Text] [Related]  

  • 9. HMG-CoA reductase inhibitor simvastatin overcomes bortezomib-induced apoptosis resistance by disrupting a geranylgeranyl pyrophosphate-dependent survival pathway.
    Fuchs D; Berges C; Opelz G; Daniel V; Naujokat C
    Biochem Biophys Res Commun; 2008 Sep; 374(2):309-14. PubMed ID: 18625202
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Simvastatin reduces lipoprotein-associated phospholipase A2 in lipopolysaccharide-stimulated human monocyte-derived macrophages through inhibition of the mevalonate-geranylgeranyl pyrophosphate-RhoA-p38 mitogen-activated protein kinase pathway.
    Song JX; Ren JY; Chen H
    J Cardiovasc Pharmacol; 2011 Feb; 57(2):213-22. PubMed ID: 21052011
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Prevention of Simvastatin-Induced Inhibition of Tendon Cell Proliferation and Cell Cycle Progression by Geranylgeranyl Pyrophosphate.
    Tsai WC; Yu TY; Lin LP; Cheng ML; Chen CL; Pang JH
    Toxicol Sci; 2016 Feb; 149(2):326-34. PubMed ID: 26577051
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis.
    Sadowski SM; Boufraqech M; Zhang L; Mehta A; Kapur P; Zhang Y; Li Z; Shen M; Kebebew E
    Oncotarget; 2015 Jul; 6(20):18038-49. PubMed ID: 25945839
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Simvastatin inhibits growth via apoptosis and the induction of cell cycle arrest in human melanoma cells.
    Saito A; Saito N; Mol W; Furukawa H; Tsutsumida A; Oyama A; Sekido M; Sasaki S; Yamamoto Y
    Melanoma Res; 2008 Apr; 18(2):85-94. PubMed ID: 18337644
    [TBL] [Abstract][Full Text] [Related]  

  • 14. STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells.
    Wei Z; Jiang X; Qiao H; Zhai B; Zhang L; Zhang Q; Wu Y; Jiang H; Sun X
    Cell Signal; 2013 Apr; 25(4):931-8. PubMed ID: 23333463
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phorbol 12-myristate 13-acetate inhibits FRO anaplastic human thyroid cancer cell proliferation by inducing cell cycle arrest in G1/S phase: evidence for an effect mediated by PKCdelta.
    Afrasiabi E; Ahlgren J; Bergelin N; Törnquist K
    Mol Cell Endocrinol; 2008 Sep; 292(1-2):26-35. PubMed ID: 18541361
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2-dependent smooth muscle cell migration. Inhibition by simvastatin.
    Valente AJ; Yoshida T; Izadpanah R; Delafontaine P; Siebenlist U; Chandrasekar B
    Cell Signal; 2013 Jun; 25(6):1447-56. PubMed ID: 23541442
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation.
    Lee MH; Cho YS; Han YM
    Stem Cells; 2007 Jul; 25(7):1654-63. PubMed ID: 17464088
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1.
    Lin HP; Lin CY; Huo C; Hsiao PH; Su LC; Jiang SS; Chan TM; Chang CH; Chen LT; Kung HJ; Wang HD; Chuu CP
    Oncotarget; 2015 Mar; 6(9):6684-707. PubMed ID: 25788262
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Simvastatin suppresses leptin expression in 3T3-L1 adipocytes via activation of the cyclic AMP-PKA pathway induced by inhibition of protein prenylation.
    Maeda T; Horiuchi N
    J Biochem; 2009 Jun; 145(6):771-81. PubMed ID: 19254925
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential effect of simvastatin on various signal transduction intermediates in cultured human smooth muscle cells.
    Nègre-Aminou P; van Erck M; van Leeuwen RE; Collard JG; Cohen LH
    Biochem Pharmacol; 2001 Apr; 61(8):991-8. PubMed ID: 11286990
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.