BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

242 related articles for article (PubMed ID: 29236465)

  • 21. Deciphering the genomic targets of alkylating polyamide conjugates using high-throughput sequencing.
    Chandran A; Syed J; Taylor RD; Kashiwazaki G; Sato S; Hashiya K; Bando T; Sugiyama H
    Nucleic Acids Res; 2016 May; 44(9):4014-24. PubMed ID: 27098039
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Rational design of specific binding hairpin Py-Im polyamides targeting human telomere sequences.
    Guo C; Kawamoto Y; Asamitsu S; Sawatani Y; Hashiya K; Bando T; Sugiyama H
    Bioorg Med Chem; 2015 Feb; 23(4):855-60. PubMed ID: 25614111
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Targeting the inverted CCAAT box 2 in the topoisomerase IIalpha promoter by JH-37, an imidazole-pyrrole polyamide hairpin: design, synthesis, molecular biology, and biophysical studies.
    Henry JA; Le NM; Nguyen B; Howard CM; Bailey SL; Horick SM; Buchmueller KL; Kotecha M; Hochhauser D; Hartley JA; Wilson WD; Lee M
    Biochemistry; 2004 Sep; 43(38):12249-57. PubMed ID: 15379563
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Sequence-Selective Minor Groove Recognition of a DNA Duplex Containing Synthetic Genetic Components.
    Padroni G; Withers JM; Taladriz-Sender A; Reichenbach LF; Parkinson JA; Burley GA
    J Am Chem Soc; 2019 Jun; 141(24):9555-9563. PubMed ID: 31117639
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Control of Forward/Reverse Orientation Preference of Cyclic Pyrrole-Imidazole Polyamides.
    Hirose Y; Asamitsu S; Bando T; Sugiyama H
    J Am Chem Soc; 2019 Aug; 141(33):13165-13170. PubMed ID: 31398026
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Development of pyrrole-imidazole polyamide for specific regulation of human aurora kinase-A and -B gene expression.
    Takahashi T; Asami Y; Kitamura E; Suzuki T; Wang X; Igarashi J; Morohashi A; Shinojima Y; Kanou H; Saito K; Takasu T; Nagase H; Harada Y; Kuroda K; Watanabe T; Kumamoto S; Aoyama T; Matsumoto Y; Bando T; Sugiyama H; Yoshida-Noro C; Fukuda N; Hayashi N
    Chem Biol; 2008 Aug; 15(8):829-41. PubMed ID: 18721754
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Sequence-selective single-molecule alkylation with a pyrrole-imidazole polyamide visualized in a DNA nanoscaffold.
    Yoshidome T; Endo M; Kashiwazaki G; Hidaka K; Bando T; Sugiyama H
    J Am Chem Soc; 2012 Mar; 134(10):4654-60. PubMed ID: 22320236
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Pyrrole-imidazole polyamides distinguish between double-helical DNA and RNA.
    Chenoweth DM; Meier JL; Dervan PB
    Angew Chem Int Ed Engl; 2013 Jan; 52(1):415-8. PubMed ID: 22987334
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Sequence-selective detection of double-stranded DNA sequences using pyrrole-imidazole polyamide microarrays.
    Singh I; Wendeln C; Clark AW; Cooper JM; Ravoo BJ; Burley GA
    J Am Chem Soc; 2013 Mar; 135(9):3449-57. PubMed ID: 23379840
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Strong and Specific Recognition of CAG/CTG Repeat DNA (5'-dWGCWGCW-3') by a Cyclic Pyrrole-Imidazole Polyamide.
    Hirose Y; Ohno T; Asamitsu S; Hashiya K; Bando T; Sugiyama H
    Chembiochem; 2022 Jan; 23(2):e202100533. PubMed ID: 34796607
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Orthogonal γPNA Dimerization Domains Empower DNA Binders with Cooperativity and Versatility Mimicking that of Transcription Factor Pairs.
    Yu Z; Hsieh WC; Asamitsu S; Hashiya K; Bando T; Ly DH; Sugiyama H
    Chemistry; 2018 Sep; 24(53):14183-14188. PubMed ID: 30003621
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Molecular design of hairpin imidazole-pyrrole polyamide for effective DNA alkylation.
    Bando T; Narita A; Saito I; Sugiyama H
    Nucleic Acids Res Suppl; 2001; (1):225-6. PubMed ID: 12836346
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Effect of single pyrrole replacement with β-alanine on DNA binding affinity and sequence specificity of hairpin pyrrole/imidazole polyamides targeting 5'-GCGC-3'.
    Han YW; Kashiwazaki G; Morinaga H; Matsumoto T; Hashiya K; Bando T; Harada Y; Sugiyama H
    Bioorg Med Chem; 2013 Sep; 21(17):5436-41. PubMed ID: 23810670
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA.
    Pilch DS; Poklar N; Baird EE; Dervan PB; Breslauer KJ
    Biochemistry; 1999 Feb; 38(7):2143-51. PubMed ID: 10026298
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Development of a novel gene silencer pyrrole-imidazole polyamide targeting human connective tissue growth factor.
    Wan JX; Fukuda N; Ueno T; Watanabe T; Matsuda H; Saito K; Nagase H; Matsumoto Y; Matsumoto K
    Biol Pharm Bull; 2011; 34(10):1572-7. PubMed ID: 21963497
    [TBL] [Abstract][Full Text] [Related]  

  • 36. X-ray Crystal Structure of a Cyclic-PIP-DNA Complex in the Reverse-Binding Orientation.
    Abe K; Hirose Y; Eki H; Takeda K; Bando T; Endo M; Sugiyama H
    J Am Chem Soc; 2020 Jun; 142(23):10544-10549. PubMed ID: 32401492
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Sequence-specific DNA binding by long hairpin pyrrole-imidazole polyamides containing an 8-amino-3,6-dioxaoctanoic acid unit.
    Sawatani Y; Kashiwazaki G; Chandran A; Asamitsu S; Guo C; Sato S; Hashiya K; Bando T; Sugiyama H
    Bioorg Med Chem; 2016 Aug; 24(16):3603-11. PubMed ID: 27301681
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Synthesis of pyrrole-imidazole polyamide oligomers based on a copper-catalyzed cross-coupling strategy.
    Shiga N; Takayanagi S; Muramoto R; Murakami T; Qin R; Suzuki Y; Shinohara KI; Kaneda A; Nemoto T
    Bioorg Med Chem Lett; 2017 May; 27(10):2197-2200. PubMed ID: 28389153
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Inhibition of major-groove-binding proteins by pyrrole-imidazole polyamides with an Arg-Pro-Arg positive patch.
    Bremer RE; Baird EE; Dervan PB
    Chem Biol; 1998 Mar; 5(3):119-33. PubMed ID: 9545429
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Molecular design of hairpin pyrrole-imidazole polyamides possessing sequence specific DNA alkylating moiety.
    Narita A; Bando T; Sugiyama H
    Nucleic Acids Res Suppl; 2003; (3):119-20. PubMed ID: 14510409
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.