BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

322 related articles for article (PubMed ID: 29236753)

  • 21. Functional mapping of rbOCT1 and rbOCT2 activity in the S2 segment of rabbit proximal tubule.
    Kaewmokul S; Chatsudthipong V; Evans KK; Dantzler WH; Wright SH
    Am J Physiol Renal Physiol; 2003 Dec; 285(6):F1149-59. PubMed ID: 12944320
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Characterization of human organic cation transporter 1 (OCT1/SLC22A1)- and OCT2 (SLC22A2)-mediated transport of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)- 4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide), a novel small molecule survivin suppressant.
    Minematsu T; Iwai M; Umehara K; Usui T; Kamimura H
    Drug Metab Dispos; 2010 Jan; 38(1):1-4. PubMed ID: 19833842
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Relevance of copper transporter 1 and organic cation transporters 1-3 for oxaliplatin uptake and drug resistance in colorectal cancer cells.
    Buß I; Hamacher A; Sarin N; Kassack MU; Kalayda GV
    Metallomics; 2018 Mar; 10(3):414-425. PubMed ID: 29417972
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-Mediated Uptake.
    Morse BL; Kolur A; Hudson LR; Hogan AT; Chen LH; Brackman RM; Sawada GA; Fallon JK; Smith PC; Hillgren KM
    Drug Metab Dispos; 2020 Feb; 48(2):93-105. PubMed ID: 31771949
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Association of genetic variation in the organic cation transporters OCT1, OCT2 and multidrug and toxin extrusion 1 transporter protein genes with the gastrointestinal side effects and lower BMI in metformin-treated type 2 diabetes patients.
    Tarasova L; Kalnina I; Geldnere K; Bumbure A; Ritenberga R; Nikitina-Zake L; Fridmanis D; Vaivade I; Pirags V; Klovins J
    Pharmacogenet Genomics; 2012 Sep; 22(9):659-66. PubMed ID: 22735389
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Effects of OCT1 polymorphisms on the cellular uptake, plasma concentrations and efficacy of the 5-HT(3) antagonists tropisetron and ondansetron.
    Tzvetkov MV; Saadatmand AR; Bokelmann K; Meineke I; Kaiser R; Brockmöller J
    Pharmacogenomics J; 2012 Feb; 12(1):22-9. PubMed ID: 20921968
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.
    Urakami Y; Okuda M; Masuda S; Saito H; Inui KI
    J Pharmacol Exp Ther; 1998 Nov; 287(2):800-5. PubMed ID: 9808712
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Genetically polymorphic OCT1: another piece in the puzzle of the variable pharmacokinetics and pharmacodynamics of the opioidergic drug tramadol.
    Tzvetkov MV; Saadatmand AR; Lötsch J; Tegeder I; Stingl JC; Brockmöller J
    Clin Pharmacol Ther; 2011 Jul; 90(1):143-50. PubMed ID: 21562485
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Imatinib Uptake into Cells is Not Mediated by Organic Cation Transporters OCT1, OCT2, or OCT3, But is Influenced by Extracellular pH.
    Blanc Mettral J; Faller N; Cruchon S; Sottas L; Buclin T; Schild L; Choong E; Nahimana A; Decosterd LA
    Drug Metab Lett; 2019; 13(2):102-110. PubMed ID: 30734690
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Enhanced and Persistent Inhibition of Organic Cation Transporter 1 Activity by Preincubation of Cyclosporine A.
    Panfen E; Chen W; Zhang Y; Sinz M; Marathe P; Gan J; Shen H
    Drug Metab Dispos; 2019 Nov; 47(11):1352-1360. PubMed ID: 31427432
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The prototypic pharmacogenetic drug debrisoquine is a substrate of the genetically polymorphic organic cation transporter OCT1.
    Saadatmand AR; Tadjerpisheh S; Brockmöller J; Tzvetkov MV
    Biochem Pharmacol; 2012 May; 83(10):1427-34. PubMed ID: 22342776
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Genetic variants of organic cation transporter 2 (OCT2) significantly reduce metformin uptake in oocytes.
    Song IS; Shin HJ; Shin JG
    Xenobiotica; 2008 Sep; 38(9):1252-62. PubMed ID: 18728938
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Organic cation transporter-mediated drug-drug interaction potential between berberine and metformin.
    Kwon M; Choi YA; Choi MK; Song IS
    Arch Pharm Res; 2015; 38(5):849-56. PubMed ID: 25359200
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Differences in Metformin and Thiamine Uptake between Human and Mouse Organic Cation Transporter 1: Structural Determinants and Potential Consequences for Intrahepatic Concentrations.
    Meyer MJ; Tuerkova A; Römer S; Wenzel C; Seitz T; Gaedcke J; Oswald S; Brockmöller J; Zdrazil B; Tzvetkov MV
    Drug Metab Dispos; 2020 Dec; 48(12):1380-1392. PubMed ID: 33037045
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Extraneuronal monoamine transporter and organic cation transporters 1 and 2: a review of transport efficiency.
    Schömig E; Lazar A; Gründemann D
    Handb Exp Pharmacol; 2006; (175):151-80. PubMed ID: 16722235
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Selective Inhibition of Organic Cation Transporter 1 by Benzoylpaeoniflorin Attenuates Hepatic Lipid Accumulation through AMPK Activation.
    Bi Y; Wang X; Han L; Tian Y; Bo T; Li C; Shi B; Gui C; Zhang Y
    J Nat Prod; 2023 Jan; 86(1):191-198. PubMed ID: 36563333
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Inhibitory and facilitory actions of isocyanine derivatives at human and rat organic cation transporters 1, 2 and 3: a comparison to human alpha 1- and alpha 2-adrenoceptor subtypes.
    Amphoux A; Millan MJ; Cordi A; Bönisch H; Vialou V; Mannoury la Cour C; Dupuis DS; Giros B; Gautron S
    Eur J Pharmacol; 2010 May; 634(1-3):1-9. PubMed ID: 20170649
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin.
    Tzvetkov MV; Vormfelde SV; Balen D; Meineke I; Schmidt T; Sehrt D; Sabolić I; Koepsell H; Brockmöller J
    Clin Pharmacol Ther; 2009 Sep; 86(3):299-306. PubMed ID: 19536068
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Sitagliptin attenuates metformin-mediated AMPK phosphorylation through inhibition of organic cation transporters.
    Choi MK; Jin QR; Ahn SH; Bae MA; Song IS
    Xenobiotica; 2010 Dec; 40(12):817-25. PubMed ID: 20863201
    [TBL] [Abstract][Full Text] [Related]  

  • 40. An in vitro study on interaction of anisodine and monocrotaline with organic cation transporters of the SLC22 and SLC47 families.
    Chen JY; Brockmöller J; Tzvetkov MV; Wang LJ; Chen XJ
    Chin J Nat Med; 2019 Jul; 17(7):490-497. PubMed ID: 31514980
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 17.