BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

283 related articles for article (PubMed ID: 29236775)

  • 1. Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60.
    Wang F; Wang L; Wu J; Sokirniy I; Nguyen P; Bregnard T; Weinstock J; Mattern M; Bezsonova I; Hancock WW; Kumar S
    PLoS One; 2017; 12(12):e0189744. PubMed ID: 29236775
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3+ T-regulatory Cell Function and Promotes Antitumor Immunity.
    Wang L; Kumar S; Dahiya S; Wang F; Wu J; Newick K; Han R; Samanta A; Beier UH; Akimova T; Bhatti TR; Nicholson B; Kodrasov MP; Agarwal S; Sterner DE; Gu W; Weinstock J; Butt TR; Albelda SM; Hancock WW
    EBioMedicine; 2016 Nov; 13():99-112. PubMed ID: 27769803
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity.
    van Loosdregt J; Fleskens V; Fu J; Brenkman AB; Bekker CP; Pals CE; Meerding J; Berkers CR; Barbi J; Gröne A; Sijts AJ; Maurice MM; Kalkhoven E; Prakken BJ; Ovaa H; Pan F; Zaiss DM; Coffer PJ
    Immunity; 2013 Aug; 39(2):259-71. PubMed ID: 23973222
    [TBL] [Abstract][Full Text] [Related]  

  • 4. USP7 is a novel Deubiquitinase sustaining PLK1 protein stability and regulating chromosome alignment in mitosis.
    Peng Y; Liu Y; Gao Y; Yuan B; Qi X; Fu Y; Zhu Q; Cao T; Zhang S; Yin L; Li X
    J Exp Clin Cancer Res; 2019 Nov; 38(1):468. PubMed ID: 31730000
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Recent advances in the development of ubiquitin-specific-processing protease 7 (USP7) inhibitors.
    Li P; Liu HM
    Eur J Med Chem; 2020 Apr; 191():112107. PubMed ID: 32092586
    [TBL] [Abstract][Full Text] [Related]  

  • 6. USP7 small-molecule inhibitors interfere with ubiquitin binding.
    Kategaya L; Di Lello P; Rougé L; Pastor R; Clark KR; Drummond J; Kleinheinz T; Lin E; Upton JP; Prakash S; Heideker J; McCleland M; Ritorto MS; Alessi DR; Trost M; Bainbridge TW; Kwok MCM; Ma TP; Stiffler Z; Brasher B; Tang Y; Jaishankar P; Hearn BR; Renslo AR; Arkin MR; Cohen F; Yu K; Peale F; Gnad F; Chang MT; Klijn C; Blackwood E; Martin SE; Forrest WF; Ernst JA; Ndubaku C; Wang X; Beresini MH; Tsui V; Schwerdtfeger C; Blake RA; Murray J; Maurer T; Wertz IE
    Nature; 2017 Oct; 550(7677):534-538. PubMed ID: 29045385
    [TBL] [Abstract][Full Text] [Related]  

  • 7. USP7-Specific Inhibitors Target and Modify the Enzyme's Active Site via Distinct Chemical Mechanisms.
    Pozhidaeva A; Valles G; Wang F; Wu J; Sterner DE; Nguyen P; Weinstock J; Kumar KGS; Kanyo J; Wright D; Bezsonova I
    Cell Chem Biol; 2017 Dec; 24(12):1501-1512.e5. PubMed ID: 29056420
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism.
    Schauer NJ; Liu X; Magin RS; Doherty LM; Chan WC; Ficarro SB; Hu W; Roberts RM; Iacob RE; Stolte B; Giacomelli AO; Perera S; McKay K; Boswell SA; Weisberg EL; Ray A; Chauhan D; Dhe-Paganon S; Anderson KC; Griffin JD; Li J; Hahn WC; Sorger PK; Engen JR; Stegmaier K; Marto JA; Buhrlage SJ
    Sci Rep; 2020 Mar; 10(1):5324. PubMed ID: 32210275
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Deubiquitination of Tip60 by USP7 determines the activity of the p53-dependent apoptotic pathway.
    Dar A; Shibata E; Dutta A
    Mol Cell Biol; 2013 Aug; 33(16):3309-20. PubMed ID: 23775119
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mouse Double Minute 2 Homolog-Mediated Ubiquitination Facilitates Forkhead Box P3 Stability and Positively Modulates Human Regulatory T Cell Function.
    Wang A; Yang M; Liang R; Zhu F; Zhu F; Liu X; Han Y; Lin R; Wang X; Li D; Li H; Yuan X; Zhao H; Li B
    Front Immunol; 2020; 11():1087. PubMed ID: 32636834
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of CD4
    Khosravi M; Bidmeshkipour A; Cohen JL; Moravej A; Hojjat-Assari S; Naserian S; Karimi MH
    Stem Cell Res Ther; 2018 Oct; 9(1):273. PubMed ID: 30359308
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The deubiquitinase USP7 uses a distinct ubiquitin-like domain to deubiquitinate NF-ĸB subunits.
    Mitxitorena I; Somma D; Mitchell JP; Lepistö M; Tyrchan C; Smith EL; Kiely PA; Walden H; Keeshan K; Carmody RJ
    J Biol Chem; 2020 Aug; 295(33):11754-11763. PubMed ID: 32587091
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status.
    Wang M; Zhang Y; Wang T; Zhang J; Zhou Z; Sun Y; Wang S; Shi Y; Luan X; Zhang Y; Wang Y; Wang Y; Zou Z; Kang L; Liu H
    Cell Physiol Biochem; 2017; 43(5):1755-1766. PubMed ID: 29049989
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting ubiquitin specific protease 7 in cancer: A deubiquitinase with great prospects.
    Yeasmin Khusbu F; Chen FZ; Chen HC
    Cell Biochem Funct; 2018 Jul; 36(5):244-254. PubMed ID: 29781103
    [TBL] [Abstract][Full Text] [Related]  

  • 15. USP7: Target Validation and Drug Discovery for Cancer Therapy.
    Zhou J; Wang J; Chen C; Yuan H; Wen X; Sun H
    Med Chem; 2018; 14(1):3-18. PubMed ID: 29065837
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The emerging nature of Ubiquitin-specific protease 7 (USP7): a new target in cancer therapy.
    Nininahazwe L; Liu B; He C; Zhang H; Chen ZS
    Drug Discov Today; 2021 Feb; 26(2):490-502. PubMed ID: 33157193
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyanopyrrolidine Inhibitors of Ubiquitin Specific Protease 7 Mediate Desulfhydration of the Active-Site Cysteine.
    Bashore C; Jaishankar P; Skelton NJ; Fuhrmann J; Hearn BR; Liu PS; Renslo AR; Dueber EC
    ACS Chem Biol; 2020 Jun; 15(6):1392-1400. PubMed ID: 32302100
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, biological evaluation and structure-activity relationship study of quinazolin-4(3H)-one derivatives as novel USP7 inhibitors.
    Li P; Liu Y; Yang H; Liu HM
    Eur J Med Chem; 2021 Apr; 216():113291. PubMed ID: 33684824
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deubiquitinase USP7 regulates
    Cui L; Song W; Zeng Y; Wu Q; Fan Z; Huang T; Zeng B; Zhang M; Ni Q; Li Y; Wang T; Li D; Mao X; Lian T; Yang D; Yang M; Fan X
    Aging (Albany NY); 2020 Nov; 12(22):23082-23095. PubMed ID: 33221768
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Histone acetyltransferase mediated regulation of FOXP3 acetylation and Treg function.
    Xiao Y; Li B; Zhou Z; Hancock WW; Zhang H; Greene MI
    Curr Opin Immunol; 2010 Oct; 22(5):583-91. PubMed ID: 20869864
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.