BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

706 related articles for article (PubMed ID: 29237730)

  • 1. An allosteric binding site of the α7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine-binding protein.
    Delbart F; Brams M; Gruss F; Noppen S; Peigneur S; Boland S; Chaltin P; Brandao-Neto J; von Delft F; Touw WG; Joosten RP; Liekens S; Tytgat J; Ulens C
    J Biol Chem; 2018 Feb; 293(7):2534-2545. PubMed ID: 29237730
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor.
    Spurny R; Debaveye S; Farinha A; Veys K; Vos AM; Gossas T; Atack J; Bertrand S; Bertrand D; Danielson UH; Tresadern G; Ulens C
    Proc Natl Acad Sci U S A; 2015 May; 112(19):E2543-52. PubMed ID: 25918415
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Substituted 2-Aminopyrimidines Selective for α7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins.
    Kaczanowska K; Camacho Hernandez GA; Bendiks L; Kohs L; Cornejo-Bravo JM; Harel M; Finn MG; Taylor P
    J Am Chem Soc; 2017 Mar; 139(10):3676-3684. PubMed ID: 28221788
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Multiple interaction regions in the orthosteric ligand binding domain of the α7 neuronal nicotinic acetylcholine receptor.
    Xiao Y; Hammond PS; Mazurov AA; Yohannes D
    J Chem Inf Model; 2012 Nov; 52(11):3064-73. PubMed ID: 23092444
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Allosteric Agonism of
    Gulsevin A; Papke RL; Stokes C; Garai S; Thakur GA; Quadri M; Horenstein NA
    Mol Pharmacol; 2019 Jun; 95(6):606-614. PubMed ID: 30944209
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A human-specific, truncated α7 nicotinic receptor subunit assembles with full-length α7 and forms functional receptors with different stoichiometries.
    Lasala M; Corradi J; Bruzzone A; Esandi MDC; Bouzat C
    J Biol Chem; 2018 Jul; 293(27):10707-10717. PubMed ID: 29784875
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular interactions of type I and type II positive allosteric modulators with the human α7 nicotinic acetylcholine receptor: an in silico study.
    Targowska-Duda KM; Kaczor AA; Jozwiak K; Arias HR
    J Biomol Struct Dyn; 2019 Feb; 37(2):411-439. PubMed ID: 29363414
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification by virtual screening and functional characterisation of novel positive and negative allosteric modulators of the α7 nicotinic acetylcholine receptor.
    Smelt CLC; Sanders VR; Newcombe J; Burt RP; Sheppard TD; Topf M; Millar NS
    Neuropharmacology; 2018 Sep; 139():194-204. PubMed ID: 30009834
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Potentiation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site.
    Young GT; Zwart R; Walker AS; Sher E; Millar NS
    Proc Natl Acad Sci U S A; 2008 Sep; 105(38):14686-91. PubMed ID: 18791069
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Critical Molecular Determinants of α7 Nicotinic Acetylcholine Receptor Allosteric Activation: SEPARATION OF DIRECT ALLOSTERIC ACTIVATION AND POSITIVE ALLOSTERIC MODULATION.
    Horenstein NA; Papke RL; Kulkarni AR; Chaturbhuj GU; Stokes C; Manther K; Thakur GA
    J Biol Chem; 2016 Mar; 291(10):5049-67. PubMed ID: 26742843
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine.
    Nys M; Wijckmans E; Farinha A; Yoluk Ö; Andersson M; Brams M; Spurny R; Peigneur S; Tytgat J; Lindahl E; Ulens C
    Proc Natl Acad Sci U S A; 2016 Oct; 113(43):E6696-E6703. PubMed ID: 27791038
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Real-time tilting and twisting motions of ligand-bound states of α7 nicotinic acetylcholine receptor.
    Yang Y; Arai T; Sasaki D; Kuramochi M; Inagaki H; Ohashi S; Sekiguchi H; Mio K; Kubo T; Sasaki YC
    Eur Biophys J; 2024 Feb; 53(1-2):15-25. PubMed ID: 38233601
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure and allosteric activity of a single-disulfide conopeptide from
    Mohan MK; Abraham N; R P R; Jayaseelan BF; Ragnarsson L; Lewis RJ; Sarma SP
    J Biol Chem; 2020 May; 295(20):7096-7112. PubMed ID: 32234761
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PNU-120596, a positive allosteric modulator of mammalian α7 nicotinic acetylcholine receptor, is a negative modulator of ligand-gated chloride-selective channels of the gastropod Lymnaea stagnalis.
    Vulfius CA; Lebedev DS; Kryukova EV; Kudryavtsev DS; Kolbaev SN; Utkin YN; Tsetlin VI
    J Neurochem; 2020 Nov; 155(3):274-284. PubMed ID: 32248535
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Heteromeric Neuronal Nicotinic Acetylcholine Receptors with Mutant
    Stokes C; Garai S; Kulkarni AR; Cantwell LN; Noviello CM; Hibbs RE; Horenstein NA; Abboud KA; Thakur GA; Papke RL
    J Pharmacol Exp Ther; 2019 Aug; 370(2):252-268. PubMed ID: 31175218
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In search of allosteric modulators of a7-nAChR by solvent density guided virtual screening.
    Dey R; Chen L
    J Biomol Struct Dyn; 2011 Apr; 28(5):695-715. PubMed ID: 21294583
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor: ligand interactions with distinct binding sites and evidence for a prominent role of the M2-M3 segment.
    Bertrand D; Bertrand S; Cassar S; Gubbins E; Li J; Gopalakrishnan M
    Mol Pharmacol; 2008 Nov; 74(5):1407-16. PubMed ID: 18678621
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Agonist activation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site.
    Gill JK; Savolainen M; Young GT; Zwart R; Sher E; Millar NS
    Proc Natl Acad Sci U S A; 2011 Apr; 108(14):5867-72. PubMed ID: 21436053
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Theoretical study of the binding profile of an allosteric modulator NS-1738 with a chimera structure of the α7 nicotinic acetylcholine receptor.
    Kuang G; Wang X; Halldin C; Nordberg A; Långström B; Ågren H; Tu Y
    Phys Chem Chem Phys; 2016 Oct; 18(40):28003-28009. PubMed ID: 27711412
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Understanding the Bases of Function and Modulation of α7 Nicotinic Receptors: Implications for Drug Discovery.
    Corradi J; Bouzat C
    Mol Pharmacol; 2016 Sep; 90(3):288-99. PubMed ID: 27190210
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 36.