BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

246 related articles for article (PubMed ID: 29241652)

  • 1. Acute administration of roflumilast enhances immediate recall of verbal word memory in healthy young adults.
    Van Duinen MA; Sambeth A; Heckman PRA; Smit S; Tsai M; Lahu G; Uz T; Blokland A; Prickaerts J
    Neuropharmacology; 2018 Mar; 131():31-38. PubMed ID: 29241652
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Acute treatment with the PDE4 inhibitor roflumilast improves verbal word memory in healthy old individuals: a double-blind placebo-controlled study.
    Blokland A; Van Duinen MA; Sambeth A; Heckman PRA; Tsai M; Lahu G; Uz T; Prickaerts J
    Neurobiol Aging; 2019 May; 77():37-43. PubMed ID: 30776650
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acute administration of roflumilast enhances sensory gating in healthy young humans in a randomized trial.
    Heckman PRA; Van Duinen MA; Blokland A; Uz T; Prickaerts J; Sambeth A
    Psychopharmacology (Berl); 2018 Jan; 235(1):301-308. PubMed ID: 29098341
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A proof of concept phase II study with the PDE-4 inhibitor roflumilast in patients with mild cognitive impairment or mild Alzheimer's disease dementia (ROMEMA): study protocol of a double-blind, randomized, placebo-controlled, between-subjects trial.
    Possemis N; Verhey F; Prickaerts J; Blokland A; Ramakers I
    Trials; 2024 Mar; 25(1):162. PubMed ID: 38438923
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An experimental medicine study of the phosphodiesterase-4 inhibitor, roflumilast, on working memory-related brain activity and episodic memory in schizophrenia patients.
    Gilleen J; Farah Y; Davison C; Kerins S; Valdearenas L; Uz T; Lahu G; Tsai M; Ogrinc F; Reichenberg A; Williams SC; Mehta MA; Shergill SS
    Psychopharmacology (Berl); 2021 May; 238(5):1279-1289. PubMed ID: 30536081
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of rolipram and roflumilast, phosphodiesterase-4 inhibitors, on hypertension-induced defects in memory function in rats.
    Jabaris SG; Sumathy H; Kumar RS; Narayanan S; Thanikachalam S; Babu CS
    Eur J Pharmacol; 2015 Jan; 746():138-47. PubMed ID: 25446433
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Phosphodiesterase-4 Inhibitor Roflumilast, a Potential Treatment for the Comorbidity of Memory Loss and Depression in Alzheimer's Disease: A Preclinical Study in APP/PS1 Transgenic Mice.
    Wang H; Zhang FF; Xu Y; Fu HR; Wang XD; Wang L; Chen W; Xu XY; Gao YF; Zhang JG; Zhang HT
    Int J Neuropsychopharmacol; 2020 Dec; 23(10):700-711. PubMed ID: 32645141
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Preliminary evidence for the phosphodiesterase type-4 inhibitor, roflumilast, in ameliorating cognitive flexibility deficits in patients with schizophrenia.
    Livingston NR; Hawkins PC; Gilleen J; Ye R; Valdearenas L; Shergill SS; Mehta MA
    J Psychopharmacol; 2021 Sep; 35(9):1099-1110. PubMed ID: 33908296
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Roflumilast ameliorates cognitive impairment in APP/PS1 mice via cAMP/CREB/BDNF signaling and anti-neuroinflammatory effects.
    Feng H; Wang C; He W; Wu X; Li S; Zeng Z; Wei M; He B
    Metab Brain Dis; 2019 Apr; 34(2):583-591. PubMed ID: 30610438
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The effects of roflumilast, a phosphodiesterase type-4 inhibitor, on EEG biomarkers in schizophrenia: A randomised controlled trial.
    Gilleen J; Nottage J; Yakub F; Kerins S; Valdearenas L; Uz T; Lahu G; Tsai M; Ogrinc F; Williams SC; Ffytche D; Mehta MA; Shergill SS
    J Psychopharmacol; 2021 Jan; 35(1):15-22. PubMed ID: 32854568
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The preclinical pharmacology of roflumilast--a selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease.
    Hatzelmann A; Morcillo EJ; Lungarella G; Adnot S; Sanjar S; Beume R; Schudt C; Tenor H
    Pulm Pharmacol Ther; 2010 Aug; 23(4):235-56. PubMed ID: 20381629
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cognitive effects of methylphenidate and levodopa in healthy volunteers.
    Linssen AM; Sambeth A; Vuurman EF; Riedel WJ
    Eur Neuropsychopharmacol; 2014 Feb; 24(2):200-6. PubMed ID: 24119823
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses.
    Vanmierlo T; Creemers P; Akkerman S; van Duinen M; Sambeth A; De Vry J; Uz T; Blokland A; Prickaerts J
    Behav Brain Res; 2016 Apr; 303():26-33. PubMed ID: 26794595
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphodiesterase-4 inhibitors ameliorates cognitive deficits in deoxycorticosterone acetate induced hypertensive rats via cAMP/CREB signaling system.
    Jabaris SS; Sumathy H; Girish R; Narayanan S; Sugumar M; Saravana Babu C; Thanikachalam S; Thanikachalam M
    Brain Res; 2015 Oct; 1622():279-91. PubMed ID: 26168894
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Nonhuman Primate PET Study: Measurement of Brain PDE4 Occupancy by Roflumilast Using (R)-[
    Takano A; Uz T; Garcia-Segovia J; Tsai M; Lahu G; Amini N; Nakao R; Jia Z; Halldin C
    Mol Imaging Biol; 2018 Aug; 20(4):615-622. PubMed ID: 29441434
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The phosphodiesterase-4 inhibitor roflumilast decreases ethanol consumption in C57BL/6J mice.
    Liu X; Hao PD; Yang MF; Sun JY; Mao LL; Fan CD; Zhang ZY; Li DW; Yang XY; Sun BL; Zhang HT
    Psychopharmacology (Berl); 2017 Aug; 234(16):2409-2419. PubMed ID: 28477089
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The phosphodiesterase-4 inhibitor roflumilast impacts Schistosoma mansoni ovipositing in vitro but displays only modest antischistosomal activity in vivo.
    Botros SS; El-Lakkany NM; Seif El-Din SH; William S; Sabra AN; Hammam OA; de Koning HP
    Exp Parasitol; 2020 Jan; 208():107793. PubMed ID: 31711973
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biperiden Selectively Impairs Verbal Episodic Memory in a Dose- and Time-Dependent Manner in Healthy Subjects.
    Borghans L; Sambeth A; Blokland A
    J Clin Psychopharmacol; 2020; 40(1):30-37. PubMed ID: 31834098
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of a cholinergic nootropic (WEB 1881 FU) on event-related potentials recorded in incidental and intentional memory tasks.
    Münte TF; Heinze HJ; Scholz M; Künkel H
    Neuropsychobiology; 1988; 19(3):158-68. PubMed ID: 3059222
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PDE4 inhibition reduces neointima formation and inhibits VCAM-1 expression and histone methylation in an Epac-dependent manner.
    Lehrke M; Kahles F; Makowska A; Tilstam PV; Diebold S; Marx J; Stöhr R; Hess K; Endorf EB; Bruemmer D; Marx N; Findeisen HM
    J Mol Cell Cardiol; 2015 Apr; 81():23-33. PubMed ID: 25640159
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.