BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 29251492)

  • 1. Probing Conformational States of the Finger and Thumb Subdomains of HIV-1 Reverse Transcriptase Using Double Electron-Electron Resonance Electron Paramagnetic Resonance Spectroscopy.
    Schmidt T; Tian L; Clore GM
    Biochemistry; 2018 Feb; 57(5):489-493. PubMed ID: 29251492
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Temperature-dependent equilibrium between the open and closed conformation of the p66 subunit of HIV-1 reverse transcriptase revealed by site-directed spin labelling.
    Kensch O; Restle T; Wöhrl BM; Goody RS; Steinhoff HJ
    J Mol Biol; 2000 Aug; 301(4):1029-39. PubMed ID: 10966802
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Spatial domain organization in the HIV-1 reverse transcriptase p66 homodimer precursor probed by double electron-electron resonance EPR.
    Schmidt T; Schwieters CD; Clore GM
    Proc Natl Acad Sci U S A; 2019 Sep; 116(36):17809-17816. PubMed ID: 31383767
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution: implications of conformational changes for polymerization and inhibition mechanisms.
    Hsiou Y; Ding J; Das K; Clark AD; Hughes SH; Arnold E
    Structure; 1996 Jul; 4(7):853-60. PubMed ID: 8805568
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Probing the Interaction between HIV-1 Protease and the Homodimeric p66/p66' Reverse Transcriptase Precursor by Double Electron-Electron Resonance EPR Spectroscopy.
    Schmidt T; Louis JM; Clore GM
    Chembiochem; 2020 Nov; 21(21):3051-3055. PubMed ID: 32558168
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Collective motions in HIV-1 reverse transcriptase: examination of flexibility and enzyme function.
    Bahar I; Erman B; Jernigan RL; Atilgan AR; Covell DG
    J Mol Biol; 1999 Jan; 285(3):1023-37. PubMed ID: 9887265
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 2.2 A resolution structure of the amino-terminal half of HIV-1 reverse transcriptase (fingers and palm subdomains).
    Unge T; Knight S; Bhikhabhai R; Lövgren S; Dauter Z; Wilson K; Strandberg B
    Structure; 1994 Oct; 2(10):953-61. PubMed ID: 7532533
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The ribonuclease H activity of the reverse transcriptases of human immunodeficiency viruses type 1 and type 2 is affected by the thumb subdomain of the small protein subunits.
    Sevilya Z; Loya S; Hughes SH; Hizi A
    J Mol Biol; 2001 Aug; 311(5):957-71. PubMed ID: 11531332
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular dynamics of HIV-1 reverse transcriptase indicates increased flexibility upon DNA binding.
    Madrid M; Lukin JA; Madura JD; Ding J; Arnold E
    Proteins; 2001 Nov; 45(3):176-82. PubMed ID: 11599020
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant.
    Das K; Ding J; Hsiou Y; Clark AD; Moereels H; Koymans L; Andries K; Pauwels R; Janssen PA; Boyer PL; Clark P; Smith RH; Kroeger Smith MB; Michejda CJ; Hughes SH; Arnold E
    J Mol Biol; 1996 Dec; 264(5):1085-100. PubMed ID: 9000632
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular mechanisms of gene regulation studied by site-directed spin labeling.
    Steinhoff HJ; Suess B
    Methods; 2003 Feb; 29(2):188-95. PubMed ID: 12606224
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Major subdomain rearrangement in HIV-1 reverse transcriptase simulated by molecular dynamics.
    Madrid M; Jacobo-Molina A; Ding J; Arnold E
    Proteins; 1999 May; 35(3):332-7. PubMed ID: 10328268
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thumbs down for HIV: domain level rearrangements do occur in the NNRTI-bound HIV-1 reverse transcriptase.
    Wright DW; Sadiq SK; De Fabritiis G; Coveney PV
    J Am Chem Soc; 2012 Aug; 134(31):12885-8. PubMed ID: 22827470
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex.
    Lansdon EB; Samuel D; Lagpacan L; Brendza KM; White KL; Hung M; Liu X; Boojamra CG; Mackman RL; Cihlar T; Ray AS; McGrath ME; Swaminathan S
    J Mol Biol; 2010 Apr; 397(4):967-78. PubMed ID: 20156454
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutagenesis of cysteine 280 of the reverse transcriptase of human immunodeficiency virus type-1: the effects on the ribonuclease H activity.
    Sevilya Z; Loya S; Duvshani A; Adir N; Hizi A
    J Mol Biol; 2003 Mar; 327(1):19-30. PubMed ID: 12614605
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Solution characterization of [methyl-(13)C]methionine HIV-1 reverse transcriptase by NMR spectroscopy.
    Zheng X; Mueller GA; DeRose EF; London RE
    Antiviral Res; 2009 Dec; 84(3):205-14. PubMed ID: 19665484
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NMR structure of the HIV-1 reverse transcriptase thumb subdomain.
    Sharaf NG; Brereton AE; Byeon IL; Karplus PA; Gronenborn AM
    J Biomol NMR; 2016 Dec; 66(4):273-280. PubMed ID: 27858311
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein-nucleic acid interactions and DNA conformation in a complex of human immunodeficiency virus type 1 reverse transcriptase with a double-stranded DNA template-primer.
    Ding J; Hughes SH; Arnold E
    Biopolymers; 1997; 44(2):125-38. PubMed ID: 9354757
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nonnucleoside inhibitor binding affects the interactions of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase with DNA.
    Peletskaya EN; Kogon AA; Tuske S; Arnold E; Hughes SH
    J Virol; 2004 Apr; 78(7):3387-97. PubMed ID: 15016861
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutating a region of HIV-1 reverse transcriptase implicated in tRNA(Lys-3) binding and the consequences for (-)-strand DNA synthesis.
    Arts EJ; Miller JT; Ehresmann B; Le Grice SF
    J Biol Chem; 1998 Jun; 273(23):14523-32. PubMed ID: 9603966
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.