BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 29253535)

  • 1. Optimizing combination of liver-enriched transcription factors and nuclear receptors simultaneously favors ammonia and drug metabolism in liver cells.
    Su Y; Chen Z; Yan L; Lian F; You J; Wang X; Tang N
    Exp Cell Res; 2018 Jan; 362(2):504-514. PubMed ID: 29253535
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CCAAT-enhancer binding protein-α (C/EBPα) and hepatocyte nuclear factor 4α (HNF4α) regulate expression of the human fructose-1,6-bisphosphatase 1 (FBP1) gene in human hepatocellular carcinoma HepG2 cells.
    Wattanavanitchakorn S; Rojvirat P; Chavalit T; MacDonald MJ; Jitrapakdee S
    PLoS One; 2018; 13(3):e0194252. PubMed ID: 29566023
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MicroRNA-561 promotes acetaminophen-induced hepatotoxicity in HepG2 cells and primary human hepatocytes through downregulation of the nuclear receptor corepressor dosage-sensitive sex-reversal adrenal hypoplasia congenital critical region on the X chromosome, gene 1 (DAX-1).
    Li M; Yang Y; He ZX; Zhou ZW; Yang T; Guo P; Zhang X; Zhou SF
    Drug Metab Dispos; 2014 Jan; 42(1):44-61. PubMed ID: 24104199
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4α upregulation in primary human hepatocytes.
    Rulcova A; Krausova L; Smutny T; Vrzal R; Dvorak Z; Jover R; Pavek P
    Pharmacol Rep; 2013; 65(5):1322-35. PubMed ID: 24399729
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stable overexpression of arginase I and ornithine transcarbamylase in HepG2 cells improves its ammonia detoxification.
    Tang N; Wang Y; Wang X; Zhou L; Zhang F; Li X; Chen Y
    J Cell Biochem; 2012 Feb; 113(2):518-27. PubMed ID: 21938740
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Simultaneous recovery of dual pathways for ammonia metabolism do not improve further detoxification of ammonia in HepG2 cells.
    Zhang FY; Tang NH; Wang XQ; Li XJ; Chen YL
    Hepatobiliary Pancreat Dis Int; 2013 Oct; 12(5):525-32. PubMed ID: 24103284
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Generation of carbamoyl phosphate synthetase 1 reporter cell lines for the assessment of ammonia metabolism.
    Wang Y; Chang L; Zhai J; Wu Q; Wang D; Wang Y
    J Cell Mol Med; 2017 Dec; 21(12):3214-3223. PubMed ID: 28557353
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lower expression of HNF4α and PGC1α might impair rifampicin-mediated CYP3A4 induction under conditions where PXR is overexpressed in human fetal liver cells.
    Takezawa T; Matsunaga T; Aikawa K; Nakamura K; Ohmori S
    Drug Metab Pharmacokinet; 2012; 27(4):430-8. PubMed ID: 22333269
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of Liver Enriched Transcription Factors in Rat Hepatocytes Cultures on Collagen and EHS Sarcoma Matrices.
    Borlak J; Singh PK; Rittelmeyer I
    PLoS One; 2015; 10(4):e0124867. PubMed ID: 25901575
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Underexpressed coactivators PGC1alpha and SRC1 impair hepatocyte nuclear factor 4 alpha function and promote dedifferentiation in human hepatoma cells.
    Martínez-Jiménez CP; Gómez-Lechón MJ; Castell JV; Jover R
    J Biol Chem; 2006 Oct; 281(40):29840-9. PubMed ID: 16891307
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Epigenetic Modifications of the Liver Tumor Cell Line HepG2 Increase Their Drug Metabolic Capacity.
    Ruoß M; Damm G; Vosough M; Ehret L; Grom-Baumgarten C; Petkov M; Naddalin S; Ladurner R; Seehofer D; Nussler A; Sajadian S
    Int J Mol Sci; 2019 Jan; 20(2):. PubMed ID: 30654452
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transcriptional activation of CYP2C9, CYP1A1, and CYP1A2 by hepatocyte nuclear factor 4alpha requires coactivators peroxisomal proliferator activated receptor-gamma coactivator 1alpha and steroid receptor coactivator 1.
    Martínez-Jiménez CP; Castell JV; Gómez-Lechón MJ; Jover R
    Mol Pharmacol; 2006 Nov; 70(5):1681-92. PubMed ID: 16882880
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of hepatocyte nuclear factors in transcriptional regulation of male-specific CYP2A2.
    Wiwi CA; Waxman DJ
    J Biol Chem; 2005 Feb; 280(5):3259-68. PubMed ID: 15539409
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ornithine transcarbamylase and arginase I deficiency are responsible for diminished urea cycle function in the human hepatoblastoma cell line HepG2.
    Mavri-Damelin D; Eaton S; Damelin LH; Rees M; Hodgson HJ; Selden C
    Int J Biochem Cell Biol; 2007; 39(3):555-64. PubMed ID: 17098461
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PXR Suppresses PPARα-Dependent
    Shizu R; Ezaki K; Sato T; Sugawara A; Hosaka T; Sasaki T; Yoshinari K
    Cells; 2021 Dec; 10(12):. PubMed ID: 34944058
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antiepileptic Drug-Activated Constitutive Androstane Receptor Inhibits Peroxisome Proliferator-Activated Receptor
    Shizu R; Otsuka Y; Ezaki K; Ishii C; Arakawa S; Amaike Y; Abe T; Hosaka T; Sasaki T; Kanno Y; Miyata M; Yamazoe Y; Yoshinari K
    Mol Pharmacol; 2020 Nov; 98(5):634-647. PubMed ID: 32892155
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Defective ureagenesis in mice carrying a liver-specific disruption of hepatocyte nuclear factor 4alpha (HNF4alpha ). HNF4alpha regulates ornithine transcarbamylase in vivo.
    Inoue Y; Hayhurst GP; Inoue J; Mori M; Gonzalez FJ
    J Biol Chem; 2002 Jul; 277(28):25257-65. PubMed ID: 11994307
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Growth hormone regulates the expression of hepatocyte nuclear factor-3 gamma and other liver-enriched transcription factors in the bovine liver.
    Eleswarapu S; Jiang H
    J Endocrinol; 2005 Jan; 184(1):95-105. PubMed ID: 15642787
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CCAAT/enhancer-binding protein alpha (C/EBPalpha) and hepatocyte nuclear factor 4alpha (HNF4alpha) synergistically cooperate with constitutive androstane receptor to transactivate the human cytochrome P450 2B6 (CYP2B6) gene: application to the development of a metabolically competent human hepatic cell model.
    Benet M; Lahoz A; Guzmán C; Castell JV; Jover R
    J Biol Chem; 2010 Sep; 285(37):28457-71. PubMed ID: 20622021
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hepatocyte nuclear factor 4α (HNF4α) in coordination with retinoic acid receptors increases all-trans-retinoic acid-dependent CYP26A1 gene expression in HepG2 human hepatocytes.
    Zolfaghari R; Ross AC
    J Cell Biochem; 2014 Oct; 115(10):1740-51. PubMed ID: 24819304
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.