BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 2925655)

  • 1. Inhibitors of sterol synthesis. Characterization of side chain oxygenated derivatives formed upon incubation of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one with rat liver mitochondria.
    Pyrek JS; Vermilion JL; Stephens TW; Wilson WK; Schroepfer GJ
    J Biol Chem; 1989 Mar; 264(8):4536-43. PubMed ID: 2925655
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibitors of sterol synthesis. Spectral characterization of derivatives of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one.
    St Pyrek J; Wilson WK; Schroepfer GJ
    J Lipid Res; 1987 Nov; 28(11):1296-307. PubMed ID: 3430060
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibitors of sterol synthesis. Chemical synthesis and spectral properties of 3 beta-hydroxy-5 alpha-cholesta-8(14),24-dien-15-one, 3 beta,25-dihydroxy-5 alpha-cholest-8(14)-en-15-one, and 3 beta,24-dihydroxy-5 alpha-cholest-8(14)-en-15-one and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.
    Swaminathan S; Pinkerton FD; Numazawa S; Wilson WK; Schroepfer GJ
    J Lipid Res; 1992 Oct; 33(10):1503-15. PubMed ID: 1431575
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibitors of sterol synthesis. Synthesis and spectral characterization of fatty acids esters of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one.
    St Pyrek J; Schroepfer GJ
    J Lipid Res; 1987 Nov; 28(11):1308-12. PubMed ID: 3430061
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibitors of sterol synthesis. Chemical syntheses and spectral properties of 26-oxygenated derivatives of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.
    Siddiqui AU; Wilson WK; Ruecker KE; Pinkerton FD; Schroepfer GJ
    Chem Phys Lipids; 1992 Nov; 63(1-2):77-90. PubMed ID: 1486662
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibitors of sterol synthesis. Characterization of trimethylsilyl dienol ethers of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one. Applications in the analysis of mitochondrial metabolites of the 15-ketosterol by gas chromatography-mass spectrometry.
    St Pyrek J; Wilson WK; Numazawa S; Schoepfer GJ
    J Lipid Res; 1991 Aug; 32(8):1371-80. PubMed ID: 1770319
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibitors of cholesterol biosynthesis. Further studies of the metabolism of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one in rat liver preparations.
    Monger DJ; Schroepfer GJ
    Chem Phys Lipids; 1988 May; 47(1):21-46. PubMed ID: 3396133
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enzymatic formation and chemical synthesis of an active metabolite of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one, a potent regulator of cholesterol metabolism.
    Schroepfer GJ; Kim HS; Vermilion JL; Stephens TW; Pinkerton FD; Needleman DH; Wilson WK; St Pyrek J
    Biochem Biophys Res Commun; 1988 Feb; 151(1):130-6. PubMed ID: 3348769
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitors of sterol synthesis. Chemical synthesis and spectral properties of (25R)-5 alpha-cholest-8(14)-ene-3 beta,15 beta,26-triol, a potential metabolite of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and its effects on 3-hydroxy-3-methylglutaryl-coenzyme A reductase in CHO-K1 cells.
    Swaminathan S; Pinkerton FD; Wilson WK; Schroepfer GJ
    Chem Phys Lipids; 1992 May; 61(3):235-42. PubMed ID: 1525963
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vitro metabolism of 3beta-hydroxy-, and 3beta,14alpha-dihydroxy-[3alpha-3H]-5beta-cholest-7-en-6-one by the prothoracic glands of Manduca sexta.
    Bollenbacher WE; Galbraith MN; Gilbert LI; Horn DH
    Steroids; 1977 Jan; 29(1):47-63. PubMed ID: 190738
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibitors of sterol biosynthesis. Carbon-13 nuclear magnetic resonance studies of 9 alpha-fluoro-5 alpha-cholest-8(14)-en-3 beta-ol-15-one and related compounds.
    Tsuda M; Schroepfer GJ
    J Lipid Res; 1981 Nov; 22(8):1188-97. PubMed ID: 7320629
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibitors of sterol synthesis. Differential effects of 14 alpha-hydroxymethyl-5 alpha-cholest-7-ene-3 beta, 15 alpha-diol and 14 alpha-hydroxymethyl-5 alpha-cholest-6-ene-3 beta, 15 alpha-diol on sterol synthesis in cell-free homogenates of rat liver.
    Miller LR; Pascal RA; Schroepfer GJ
    J Biol Chem; 1981 Aug; 256(15):8085-91. PubMed ID: 7263642
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibitors of sterol synthesis. Chemical synthesis, structure, and biological activities of (25R)-3 beta,26-dihydroxy-5 alpha-cholest-8(14)-en-15-one, a metabolite of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one.
    Kim HS; Wilson WK; Needleman DH; Pinkerton FD; Wilson DK; Quiocho FA; Schroepfer GJ
    J Lipid Res; 1989 Feb; 30(2):247-61. PubMed ID: 2715729
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibitors of sterol synthesis. Chemical synthesis and properties of 3 beta-hydroxy-25,26,26,26,27,27,27-heptafluoro-5 alpha-cholest-8(14)-en-15-one and 25,26,26,26,27,27,27-heptafluorocholesterol and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells.
    Swaminathan S; Wilson WK; Pinkerton FD; Gerst N; Ramser M; Schroepfer GJ
    J Lipid Res; 1993 Oct; 34(10):1805-23. PubMed ID: 8245728
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibitors of sterol biosynthesis. Synthesis and activities of ring C oxygenated sterols.
    Schroepfer GJ; Parish EJ; Kandutsch AA
    Chem Phys Lipids; 1988 Feb; 46(2):147-54. PubMed ID: 3342458
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibitors of sterol synthesis. A highly efficient and specific side-chain oxidation of 3 beta-acetoxy-5 alpha-cholest-8(14)-en-15-one for construction of metabolites and analogs of the 15-ketosterol.
    Herz JE; Swaminathan S; Pinkerton FD; Wilson WK; Schroepfer GJ
    J Lipid Res; 1992 Apr; 33(4):579-98. PubMed ID: 1527481
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibitors of sterol synthesis. Studies of the distribution and metabolism of 5 alpha-[2,4-3H]cholest-8(14)-en-3 beta-ol-15-one after intragastric administration to rats.
    Brabson JS; Schroepfer GJ
    Steroids; 1988; 52(1-2):51-68. PubMed ID: 3247671
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sterol synthesis: studies of the metabolism of 14 alpha-methyl-5 alpha-cholest-7-en-3 beta-ol.
    Chan JT; Spike TE; Trowbridge ST; Schroepfer GJ
    J Lipid Res; 1979 Nov; 20(8):1007-19. PubMed ID: 533823
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibitors of sterol synthesis. Chemical syntheses, properties and effects of 4,4-dimethyl-15-oxygenated sterols on sterol synthesis and on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells.
    Schroepfer GJ; Parish EJ; Tsuda M; Kandutsch AA
    Chem Phys Lipids; 1988 Jul; 47(3):187-207. PubMed ID: 3168085
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis of 3 beta-hydroxy-5 alpha-cholest-8-en-7-one and 3 beta-hydroxy-5 alpha-cholest-8-en-11-one: evaluation as potential hypocholesterolemic agents.
    Parish EJ; Nanduri VB; Seikel JM; Kohl HH; Nusbaum KE
    Steroids; 1986; 48(5-6):407-18. PubMed ID: 3445290
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.