BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

357 related articles for article (PubMed ID: 29259009)

  • 21. Knockdown of c-Met enhances sensitivity to bortezomib in human multiple myeloma U266 cells via inhibiting Akt/mTOR activity.
    Que W; Chen J; Chuang M; Jiang D
    APMIS; 2012 Mar; 120(3):195-203. PubMed ID: 22339676
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Preclinical activity of EGFR and MEK1/2 inhibitors in the treatment of biliary tract carcinoma.
    Cavalloni G; Peraldo-Neia C; Varamo C; Chiorino G; Sassi F; Aglietta M; Leone F
    Oncotarget; 2016 Aug; 7(32):52354-52363. PubMed ID: 27429047
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Cholesterol-lowering drug pitavastatin targets lung cancer and angiogenesis via suppressing prenylation-dependent Ras/Raf/MEK and PI3K/Akt/mTOR signaling.
    Hu T; Shen H; Huang H; Yang Z; Zhou Y; Zhao G
    Anticancer Drugs; 2020 Apr; 31(4):377-384. PubMed ID: 32011362
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Biallelic loss of FAM46C triggers tumor growth with concomitant activation of Akt signaling in multiple myeloma cells.
    Kanasugi J; Hanamura I; Ota A; Karnan S; Lam VQ; Mizuno S; Wahiduzzaman M; Rahman ML; Hyodo T; Konishi H; Tsuzuki S; Hosokawa Y; Takami A
    Cancer Sci; 2020 May; 111(5):1663-1675. PubMed ID: 32176823
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synergistic targeted inhibition of MEK and dual PI3K/mTOR diminishes viability and inhibits tumor growth of canine melanoma underscoring its utility as a preclinical model for human mucosal melanoma.
    Wei BR; Michael HT; Halsey CH; Peer CJ; Adhikari A; Dwyer JE; Hoover SB; El Meskini R; Kozlov S; Weaver Ohler Z; Figg WD; Merlino G; Simpson RM
    Pigment Cell Melanoma Res; 2016 Nov; 29(6):643-655. PubMed ID: 27463366
    [TBL] [Abstract][Full Text] [Related]  

  • 26. MK2206 enhances the cytocidal effects of bufalin in multiple myeloma by inhibiting the AKT/mTOR pathway.
    Xiang RF; Wang Y; Zhang N; Xu WB; Cao Y; Tong J; Li JM; Wu YL; Yan H
    Cell Death Dis; 2017 May; 8(5):e2776. PubMed ID: 28492559
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Targeting MEK in a Translational Model of Histiocytic Sarcoma.
    Takada M; Hix JML; Corner S; Schall PZ; Kiupel M; Yuzbasiyan-Gurkan V
    Mol Cancer Ther; 2018 Nov; 17(11):2439-2450. PubMed ID: 30135215
    [TBL] [Abstract][Full Text] [Related]  

  • 28. CDK5 inhibition in vitro and in vivo induces cell death in myeloma and overcomes the obstacle of bortezomib resistance.
    Tang H; Xu L; Cen X; Yang L; Feng J; Li G; Zhu H; Gao S; Yu Y; Zhao Y; Tian Z; Hou L; Yu S; Gao G
    Int J Mol Med; 2020 Jun; 45(6):1661-1672. PubMed ID: 32236619
    [TBL] [Abstract][Full Text] [Related]  

  • 29. New Mechanisms of Resistance to MEK Inhibitors in Melanoma Revealed by Intravital Imaging.
    Brighton HE; Angus SP; Bo T; Roques J; Tagliatela AC; Darr DB; Karagoz K; Sciaky N; Gatza ML; Sharpless NE; Johnson GL; Bear JE
    Cancer Res; 2018 Jan; 78(2):542-557. PubMed ID: 29180473
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Renalase Expression by Melanoma and Tumor-Associated Macrophages Promotes Tumor Growth through a STAT3-Mediated Mechanism.
    Hollander L; Guo X; Velazquez H; Chang J; Safirstein R; Kluger H; Cha C; Desir GV
    Cancer Res; 2016 Jul; 76(13):3884-94. PubMed ID: 27197188
    [TBL] [Abstract][Full Text] [Related]  

  • 31. YAP1 Mediates Resistance to MEK1/2 Inhibition in Neuroblastomas with Hyperactivated RAS Signaling.
    Coggins GE; Farrel A; Rathi KS; Hayes CM; Scolaro L; Rokita JL; Maris JM
    Cancer Res; 2019 Dec; 79(24):6204-6214. PubMed ID: 31672841
    [TBL] [Abstract][Full Text] [Related]  

  • 32. INTS6 promotes colorectal cancer progression by activating of AKT and ERK signaling.
    Ding X; Chen T; Shi Q; Nan P; Wang X; Xie D; Li J
    Exp Cell Res; 2021 Oct; 407(2):112826. PubMed ID: 34508742
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Chidamide increases the sensitivity of refractory or relapsed acute myeloid leukemia cells to anthracyclines via regulation of the HDAC3 -AKT-P21-CDK2 signaling pathway.
    Wang H; Liu YC; Zhu CY; Yan F; Wang MZ; Chen XS; Wang XK; Pang BX; Li YH; Liu DH; Gao CJ; Liu SJ; Dou LP
    J Exp Clin Cancer Res; 2020 Dec; 39(1):278. PubMed ID: 33298132
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth.
    Leone E; Morelli E; Di Martino MT; Amodio N; Foresta U; Gullà A; Rossi M; Neri A; Giordano A; Munshi NC; Anderson KC; Tagliaferri P; Tassone P
    Clin Cancer Res; 2013 Apr; 19(8):2096-106. PubMed ID: 23446999
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Histone deacetylase inhibition in combination with MEK or BCL-2 inhibition in multiple myeloma.
    Ramakrishnan VG; Miller KC; Macon EP; Kimlinger TK; Haug J; Kumar S; Gonsalves WI; Rajkumar SV; Kumar SK
    Haematologica; 2019 Oct; 104(10):2061-2074. PubMed ID: 30846494
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Preclinical assessment of MEK1/2 inhibitors for neurofibromatosis type 2-associated schwannomas reveals differences in efficacy and drug resistance development.
    Fuse MA; Dinh CT; Vitte J; Kirkpatrick J; Mindos T; Plati SK; Young JI; Huang J; Carlstedt A; Franco MC; Brnjos K; Nagamoto J; Petrilli AM; Copik AJ; Soulakova JN; Bracho O; Yan D; Mittal R; Shen R; Telischi FF; Morrison H; Giovannini M; Liu XZ; Chang LS; Fernandez-Valle C
    Neuro Oncol; 2019 Mar; 21(4):486-497. PubMed ID: 30615146
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Combined targeting of MEK and the glucocorticoid receptor for the treatment of RAS-mutant multiple myeloma.
    Sriskandarajah P; De Haven Brandon A; MacLeod K; Carragher NO; Kirkin V; Kaiser M; Whittaker SR
    BMC Cancer; 2020 Mar; 20(1):269. PubMed ID: 32228485
    [TBL] [Abstract][Full Text] [Related]  

  • 38. NEDD8 Inhibition Overcomes CKS1B-Induced Drug Resistance by Upregulation of p21 in Multiple Myeloma.
    Huang J; Zhou Y; Thomas GS; Gu Z; Yang Y; Xu H; Tricot G; Zhan F
    Clin Cancer Res; 2015 Dec; 21(24):5532-42. PubMed ID: 26156395
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal.
    Michifuri Y; Hirohashi Y; Torigoe T; Miyazaki A; Fujino J; Tamura Y; Tsukahara T; Kanaseki T; Kobayashi J; Sasaki T; Takahashi A; Nakamori K; Yamaguchi A; Hiratsuka H; Sato N
    Biochem Biophys Res Commun; 2013 Sep; 439(1):96-102. PubMed ID: 23954638
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Ras association domain family member 10 suppresses gastric cancer growth by cooperating with GSTP1 to regulate JNK/c-Jun/AP-1 pathway.
    Li X; Liang Q; Liu W; Zhang N; Xu L; Zhang X; Zhang J; Sung JJ; Yu J
    Oncogene; 2016 May; 35(19):2453-64. PubMed ID: 26279301
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 18.