BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

354 related articles for article (PubMed ID: 29259012)

  • 1. FIH Is an Oxygen Sensor in Ovarian Cancer for G9a/GLP-Driven Epigenetic Regulation of Metastasis-Related Genes.
    Kang J; Shin SH; Yoon H; Huh J; Shin HW; Chun YS; Park JW
    Cancer Res; 2018 Mar; 78(5):1184-1199. PubMed ID: 29259012
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The H3K9 methyltransferase G9a is a marker of aggressive ovarian cancer that promotes peritoneal metastasis.
    Hua KT; Wang MY; Chen MW; Wei LH; Chen CK; Ko CH; Jeng YM; Sung PL; Jan YH; Hsiao M; Kuo ML; Yen ML
    Mol Cancer; 2014 Aug; 13():189. PubMed ID: 25115793
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The H3K9 Methyltransferase G9a Represses E-cadherin and is Associated with Myometrial Invasion in Endometrial Cancer.
    Hsiao SM; Chen MW; Chen CA; Chien MH; Hua KT; Hsiao M; Kuo ML; Wei LH
    Ann Surg Oncol; 2015 Dec; 22 Suppl 3():S1556-65. PubMed ID: 25613390
    [TBL] [Abstract][Full Text] [Related]  

  • 4. G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis.
    Casciello F; Al-Ejeh F; Kelly G; Brennan DJ; Ngiow SF; Young A; Stoll T; Windloch K; Hill MM; Smyth MJ; Gannon F; Lee JS
    Proc Natl Acad Sci U S A; 2017 Jul; 114(27):7077-7082. PubMed ID: 28630300
    [TBL] [Abstract][Full Text] [Related]  

  • 5. G9A promotes gastric cancer metastasis by upregulating ITGB3 in a SET domain-independent manner.
    Hu L; Zang MD; Wang HX; Zhang BG; Wang ZQ; Fan ZY; Wu H; Li JF; Su LP; Yan M; Zhu ZQ; Yang QM; Huang Q; Liu BY; Zhu ZG
    Cell Death Dis; 2018 Feb; 9(3):278. PubMed ID: 29449539
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor.
    Tarhonskaya H; Hardy AP; Howe EA; Loik ND; Kramer HB; McCullagh JS; Schofield CJ; Flashman E
    J Biol Chem; 2015 Aug; 290(32):19726-42. PubMed ID: 26112411
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Epigenetic Regulation of the PTEN-AKT-RAC1 Axis by G9a Is Critical for Tumor Growth in Alveolar Rhabdomyosarcoma.
    Bhat AV; Palanichamy Kala M; Rao VK; Pignata L; Lim HJ; Suriyamurthy S; Chang KT; Lee VK; Guccione E; Taneja R
    Cancer Res; 2019 May; 79(9):2232-2243. PubMed ID: 30833420
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ankyrin Repeat Proteins of Orf Virus Influence the Cellular Hypoxia Response Pathway.
    Chen DY; Fabrizio JA; Wilkins SE; Dave KA; Gorman JJ; Gleadle JM; Fleming SB; Peet DJ; Mercer AA
    J Virol; 2017 Jan; 91(1):. PubMed ID: 27795413
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration.
    Bao L; Chen Y; Lai HT; Wu SY; Wang JE; Hatanpaa KJ; Raisanen JM; Fontenot M; Lega B; Chiang CM; Semenza GL; Wang Y; Luo W
    Nucleic Acids Res; 2018 Jul; 46(13):6576-6591. PubMed ID: 29860315
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting histone methyltransferase G9a inhibits growth and Wnt signaling pathway by epigenetically regulating HP1α and APC2 gene expression in non-small cell lung cancer.
    Zhang K; Wang J; Yang L; Yuan YC; Tong TR; Wu J; Yun X; Bonner M; Pangeni R; Liu Z; Yuchi T; Kim JY; Raz DJ
    Mol Cancer; 2018 Oct; 17(1):153. PubMed ID: 30348169
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel.
    Karttunen S; Duffield M; Scrimgeour NR; Squires L; Lim WL; Dallas ML; Scragg JL; Chicher J; Dave KA; Whitelaw ML; Peers C; Gorman JJ; Gleadle JM; Rychkov GY; Peet DJ
    J Cell Sci; 2015 Jan; 128(2):225-31. PubMed ID: 25413349
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ferritin heavy chain controls the HIF-driven hypoxic response by activating the asparaginyl hydroxylase FIH.
    Jin P; Kang J; Lee MK; Park JW
    Biochem Biophys Res Commun; 2018 May; 499(3):475-481. PubMed ID: 29580991
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2).
    Janke K; Brockmeier U; Kuhlmann K; Eisenacher M; Nolde J; Meyer HE; Mairbäurl H; Metzen E
    J Cell Sci; 2013 Jun; 126(Pt 12):2629-40. PubMed ID: 23606740
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Histone methyltransferase G9a promotes liver cancer development by epigenetic silencing of tumor suppressor gene RARRES3.
    Wei L; Chiu DK; Tsang FH; Law CT; Cheng CL; Au SL; Lee JM; Wong CC; Ng IO; Wong CM
    J Hepatol; 2017 Oct; 67(4):758-769. PubMed ID: 28532996
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor.
    Linke S; Stojkoski C; Kewley RJ; Booker GW; Whitelaw ML; Peet DJ
    J Biol Chem; 2004 Apr; 279(14):14391-7. PubMed ID: 14734545
    [TBL] [Abstract][Full Text] [Related]  

  • 16. G9a-mediated repression of CDH10 in hypoxia enhances breast tumour cell motility and associates with poor survival outcome.
    Casciello F; Al-Ejeh F; Miranda M; Kelly G; Baxter E; Windloch K; Gannon F; Lee JS
    Theranostics; 2020; 10(10):4515-4529. PubMed ID: 32292512
    [No Abstract]   [Full Text] [Related]  

  • 17. The zinc finger proteins ZNF644 and WIZ regulate the G9a/GLP complex for gene repression.
    Bian C; Chen Q; Yu X
    Elife; 2015 Mar; 4():. PubMed ID: 25789554
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1.
    Duan Z; Zarebski A; Montoya-Durango D; Grimes HL; Horwitz M
    Mol Cell Biol; 2005 Dec; 25(23):10338-51. PubMed ID: 16287849
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of
    Dobson THW; Hatcher RJ; Swaminathan J; Das CM; Shaik S; Tao RH; Milite C; Castellano S; Taylor PH; Sbardella G; Gopalakrishnan V
    Mol Cancer Res; 2017 Aug; 15(8):1073-1084. PubMed ID: 28483947
    [TBL] [Abstract][Full Text] [Related]  

  • 20. H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM.
    Chen MW; Hua KT; Kao HJ; Chi CC; Wei LH; Johansson G; Shiah SG; Chen PS; Jeng YM; Cheng TY; Lai TC; Chang JS; Jan YH; Chien MH; Yang CJ; Huang MS; Hsiao M; Kuo ML
    Cancer Res; 2010 Oct; 70(20):7830-40. PubMed ID: 20940408
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.