These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

652 related articles for article (PubMed ID: 29262834)

  • 1. Isoprenoids responsible for protein prenylation modulate the biological effects of statins on pancreatic cancer cells.
    Gbelcová H; Rimpelová S; Knejzlík Z; Šáchová J; Kolář M; Strnad H; Repiská V; D'Acunto WC; Ruml T; Vítek L
    Lipids Health Dis; 2017 Dec; 16(1):250. PubMed ID: 29262834
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Statins inhibit blastocyst formation by preventing geranylgeranylation.
    Alarcon VB; Marikawa Y
    Mol Hum Reprod; 2016 May; 22(5):350-63. PubMed ID: 26908642
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Importance of geranylgeranyl pyrophosphate for mesangial cell DNA synthesis.
    Massy ZA; Guijarro C; Oda H; Kasiske BL; Keane WF; O'Donnell MP
    Kidney Int Suppl; 1999 Jul; 71():S80-3. PubMed ID: 10412744
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Statin-induced breast cancer cell death: role of inducible nitric oxide and arginase-dependent pathways.
    Kotamraju S; Williams CL; Kalyanaraman B
    Cancer Res; 2007 Aug; 67(15):7386-94. PubMed ID: 17671209
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Statins inhibited the MIP-1α expression via inhibition of Ras/ERK and Ras/Akt pathways in myeloma cells.
    Tsubaki M; Mashimo K; Takeda T; Kino T; Fujita A; Itoh T; Imano M; Sakaguchi K; Satou T; Nishida S
    Biomed Pharmacother; 2016 Mar; 78():23-29. PubMed ID: 26898421
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Geranylgeranyl-pyrophosphate, an isoprenoid of mevalonate cascade, is a critical compound for rat primary cultured cortical neurons to protect the cell death induced by 3-hydroxy-3-methylglutaryl-CoA reductase inhibition.
    Tanaka T; Tatsuno I; Uchida D; Moroo I; Morio H; Nakamura S; Noguchi Y; Yasuda T; Kitagawa M; Saito Y; Hirai A
    J Neurosci; 2000 Apr; 20(8):2852-9. PubMed ID: 10751437
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylation of eIF2α attenuates statin-induced apoptosis by inhibiting the stabilization and translocation of p53 to the mitochondria.
    Lee SK; Kim YS
    Int J Oncol; 2013 Mar; 42(3):810-6. PubMed ID: 23354132
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anti-tumor effects of mevalonate pathway inhibition in ovarian cancer.
    Göbel A; Zinna VM; Dell'Endice S; Jaschke N; Kuhlmann JD; Wimberger P; Rachner TD
    BMC Cancer; 2020 Jul; 20(1):703. PubMed ID: 32727400
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation.
    Lee MH; Cho YS; Han YM
    Stem Cells; 2007 Jul; 25(7):1654-63. PubMed ID: 17464088
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Apoptosis of rheumatoid synovial cells by statins through the blocking of protein geranylgeranylation: a potential therapeutic approach to rheumatoid arthritis.
    Nagashima T; Okazaki H; Yudoh K; Matsuno H; Minota S
    Arthritis Rheum; 2006 Feb; 54(2):579-86. PubMed ID: 16447234
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of farnesyl pyrophosphate accumulation on calvarial osteoblast differentiation.
    Weivoda MM; Hohl RJ
    Endocrinology; 2011 Aug; 152(8):3113-22. PubMed ID: 21586555
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 3-Hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors, atorvastatin and simvastatin, induce apoptosis of vascular smooth muscle cells by downregulation of Bcl-2 expression and Rho A prenylation.
    Blanco-Colio LM; Villa A; Ortego M; Hernández-Presa MA; Pascual A; Plaza JJ; Egido J
    Atherosclerosis; 2002 Mar; 161(1):17-26. PubMed ID: 11882313
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synergistic Antiproliferative Effects of Zoledronic Acid and Fluvastatin on Human Pancreatic Cancer Cell Lines: An in Vitro Study.
    Elsayed M; Kobayashi D; Kubota T; Matsunaga N; Murata R; Yoshizawa Y; Watanabe N; Matsuura T; Tsurudome Y; Ogino T; Ohdo S; Shimazoe T
    Biol Pharm Bull; 2016 Aug; 39(8):1238-46. PubMed ID: 27181081
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins).
    Eberlein M; Heusinger-Ribeiro J; Goppelt-Struebe M
    Br J Pharmacol; 2001 Aug; 133(7):1172-80. PubMed ID: 11487529
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase.
    Kato S; Smalley S; Sadarangani A; Chen-Lin K; Oliva B; Brañes J; Carvajal J; Gejman R; Owen GI; Cuello M
    J Cell Mol Med; 2010 May; 14(5):1180-93. PubMed ID: 19432822
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Statin-Induced Cancer Cell Death Can Be Mechanistically Uncoupled from Prenylation of RAS Family Proteins.
    Yu R; Longo J; van Leeuwen JE; Mullen PJ; Ba-Alawi W; Haibe-Kains B; Penn LZ
    Cancer Res; 2018 Mar; 78(5):1347-1357. PubMed ID: 29229608
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HMG-CoA reductase inhibitors induce apoptosis of lymphoma cells by promoting ROS generation and regulating Akt, Erk and p38 signals via suppression of mevalonate pathway.
    Qi XF; Zheng L; Lee KJ; Kim DH; Kim CS; Cai DQ; Wu Z; Qin JW; Yu YH; Kim SK
    Cell Death Dis; 2013 Feb; 4(2):e518. PubMed ID: 23449454
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Simvastatin suppresses leptin expression in 3T3-L1 adipocytes via activation of the cyclic AMP-PKA pathway induced by inhibition of protein prenylation.
    Maeda T; Horiuchi N
    J Biochem; 2009 Jun; 145(6):771-81. PubMed ID: 19254925
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Simvastatin Reduces Cancerogenic Potential of Renal Cancer Cells via Geranylgeranyl Pyrophosphate and Mevalonate Pathway.
    Woschek M; Kneip N; Jurida K; Marzi I; Relja B
    Nutr Cancer; 2016; 68(3):420-7. PubMed ID: 27042994
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mononuclear phagocyte morphological response to chemoattractants is dependent on geranylgeranyl pyrophosphate.
    Krauklis SA; Hussain J; Murphy KM; Dray EL; Ousley CG; Justyna K; Distefano MD; Steelman AJ; McKim DB
    Am J Physiol Endocrinol Metab; 2024 Jul; 327(1):E55-E68. PubMed ID: 38717364
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.