107 related articles for article (PubMed ID: 29263074)
1. In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate.
Baumgärtner F; Jourdan J; Scheurer C; Blasco B; Campo B; Mäser P; Wittlin S
Malar J; 2017 Jan; 16(1):45. PubMed ID: 28122617
[TBL] [Abstract][Full Text] [Related]
2. Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria.
Charman SA; Arbe-Barnes S; Bathurst IC; Brun R; Campbell M; Charman WN; Chiu FC; Chollet J; Craft JC; Creek DJ; Dong Y; Matile H; Maurer M; Morizzi J; Nguyen T; Papastogiannidis P; Scheurer C; Shackleford DM; Sriraghavan K; Stingelin L; Tang Y; Urwyler H; Wang X; White KL; Wittlin S; Zhou L; Vennerstrom JL
Proc Natl Acad Sci U S A; 2011 Mar; 108(11):4400-5. PubMed ID: 21300861
[TBL] [Abstract][Full Text] [Related]
3. A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile.
Ismail HM; Barton VE; Panchana M; Charoensutthivarakul S; Biagini GA; Ward SA; O'Neill PM
Angew Chem Int Ed Engl; 2016 May; 55(22):6401-5. PubMed ID: 27089538
[TBL] [Abstract][Full Text] [Related]
4. Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439.
Shackleford DM; Chiu FCK; Katneni K; Blundell S; McLaren J; Wang X; Zhou L; Sriraghavan K; Alker AM; Hunziker D; Scheurer C; Zhao Q; Dong Y; Möhrle JJ; Abla N; Matile H; Wittlin S; Vennerstrom JL; Charman SA
ACS Infect Dis; 2021 Jul; 7(7):1885-1893. PubMed ID: 34101429
[TBL] [Abstract][Full Text] [Related]
5. Anticancer properties of distinct antimalarial drug classes.
Hooft van Huijsduijnen R; Guy RK; Chibale K; Haynes RK; Peitz I; Kelter G; Phillips MA; Vennerstrom JL; Yuthavong Y; Wells TN
PLoS One; 2013; 8(12):e82962. PubMed ID: 24391728
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and antimalarial activity of amide and ester conjugates of siderophores and ozonides.
Tiwari R; Checkley L; Ferdig MT; Vennerstrom JL; Miller MJ
Biometals; 2023 Apr; 36(2):315-320. PubMed ID: 35229216
[TBL] [Abstract][Full Text] [Related]
7. Synthesis of five- and six-membered cyclic organic peroxides: Key transformations into peroxide ring-retaining products.
Terent'ev AO; Borisov DA; Vil' VA; Dembitsky VM
Beilstein J Org Chem; 2014 Jan; 10():34-114. PubMed ID: 24454562
[TBL] [Abstract][Full Text] [Related]
8. Autofluorescent antimalarials by hybridization of artemisinin and coumarin:
Herrmann L; Leidenberger M; Sacramento de Morais A; Mai C; Çapci A; da Cruz Borges Silva M; Plass F; Kahnt A; Moreira DRM; Kappes B; Tsogoeva SB
Chem Sci; 2023 Nov; 14(45):12941-12952. PubMed ID: 38023498
[TBL] [Abstract][Full Text] [Related]
9. The Parasite Reduction Ratio (PRR) Assay Version 2: Standardized Assessment of
Walz A; Duffey M; Aljayyoussi G; Sax S; Leroy D; Besson D; Burrows JN; Cherkaoui-Rbati MH; Gobeau N; Westwood MA; Siethoff C; Gamo FJ; Mäser P; Wittlin S
Pharmaceuticals (Basel); 2023 Jan; 16(2):. PubMed ID: 37009844
[TBL] [Abstract][Full Text] [Related]
10. Dimeric Artesunate Glycerophosphocholine Conjugate Nano-Assemblies as Slow-Release Antimalarials to Overcome Kelch 13 Mutant Artemisinin Resistance.
Du Y; Giannangelo C; He W; Shami GJ; Zhou W; Yang T; Creek DJ; Dogovski C; Li X; Tilley L
Antimicrob Agents Chemother; 2022 May; 66(5):e0206521. PubMed ID: 35416709
[TBL] [Abstract][Full Text] [Related]
11. Peroxide Antimalarial Drugs Target Redox Homeostasis in
Siddiqui G; Giannangelo C; De Paoli A; Schuh AK; Heimsch KC; Anderson D; Brown TG; MacRaild CA; Wu J; Wang X; Dong Y; Vennerstrom JL; Becker K; Creek DJ
ACS Infect Dis; 2022 Jan; 8(1):210-226. PubMed ID: 34985858
[No Abstract] [Full Text] [Related]
12. Multi-omic Characterization of the Mode of Action of a Potent New Antimalarial Compound, JPC-3210, Against
Birrell GW; Challis MP; De Paoli A; Anderson D; Devine SM; Heffernan GD; Jacobus DP; Edstein MD; Siddiqui G; Creek DJ
Mol Cell Proteomics; 2020 Feb; 19(2):308-325. PubMed ID: 31836637
[TBL] [Abstract][Full Text] [Related]
13. Exogenous Iron Increases Fasciocidal Activity and Hepatocellular Toxicity of the Synthetic Endoperoxides OZ78 and MT04.
Brecht K; Kirchhofer C; Bouitbir J; Trapani F; Keiser J; Krähenbühl S
Int J Mol Sci; 2019 Oct; 20(19):. PubMed ID: 31581457
[TBL] [Abstract][Full Text] [Related]
14. Parasite-Mediated Degradation of Synthetic Ozonide Antimalarials Impacts
Giannangelo C; Stingelin L; Yang T; Tilley L; Charman SA; Creek DJ
Antimicrob Agents Chemother; 2018 Mar; 62(3):. PubMed ID: 29263074
[TBL] [Abstract][Full Text] [Related]
15. System-wide biochemical analysis reveals ozonide antimalarials initially act by disrupting Plasmodium falciparum haemoglobin digestion.
Giannangelo C; Siddiqui G; De Paoli A; Anderson BM; Edgington-Mitchell LE; Charman SA; Creek DJ
PLoS Pathog; 2020 Jun; 16(6):e1008485. PubMed ID: 32589689
[TBL] [Abstract][Full Text] [Related]
16. Comparative antimalarial activities and ADME profiles of ozonides (1,2,4-trioxolanes) OZ277, OZ439, and their 1,2-dioxolane, 1,2,4-trioxane, and 1,2,4,5-tetraoxane isosteres.
Wang X; Dong Y; Wittlin S; Charman SA; Chiu FC; Chollet J; Katneni K; Mannila J; Morizzi J; Ryan E; Scheurer C; Steuten J; Santo Tomas J; Snyder C; Vennerstrom JL
J Med Chem; 2013 Mar; 56(6):2547-55. PubMed ID: 23489135
[TBL] [Abstract][Full Text] [Related]
17. The structure-activity relationship of the antimalarial ozonide arterolane (OZ277).
Dong Y; Wittlin S; Sriraghavan K; Chollet J; Charman SA; Charman WN; Scheurer C; Urwyler H; Santo Tomas J; Snyder C; Creek DJ; Morizzi J; Koltun M; Matile H; Wang X; Padmanilayam M; Tang Y; Dorn A; Brun R; Vennerstrom JL
J Med Chem; 2010 Jan; 53(1):481-91. PubMed ID: 19924861
[TBL] [Abstract][Full Text] [Related]
18.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
19.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
20.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
[Next] [New Search]
