256 related articles for article (PubMed ID: 29273084)
1. Identification of cryptolepine metabolites in rat and human hepatocytes and metabolism and pharmacokinetics of cryptolepine in Sprague Dawley rats.
Forkuo AD; Ansah C; Pearson D; Gertsch W; Cirello A; Amaral A; Spear J; Wright CW; Rynn C
BMC Pharmacol Toxicol; 2017 Dec; 18(1):84. PubMed ID: 29273084
[TBL] [Abstract][Full Text] [Related]
2. Pharmacokinetics and in vivo chemosuppressive activity studies on cryptolepine hydrochloride and cryptolepine hydrochloride-loaded gelatine nanoformulation designed for parenteral administration for the treatment of malaria.
Kuntworbe N; Ofori M; Addo P; Tingle M; Al-Kassas R
Acta Trop; 2013 Sep; 127(3):165-73. PubMed ID: 23643517
[TBL] [Abstract][Full Text] [Related]
3. Pharmacokinetics and metabolism of the antimalarial piperaquine after intravenous and oral single doses to the rat.
Tarning J; Lindegardh N; Sandberg S; Day NJ; White NJ; Ashton M
J Pharm Sci; 2008 Aug; 97(8):3400-10. PubMed ID: 17969131
[TBL] [Abstract][Full Text] [Related]
4. In vitro drug metabolism of green tea catechins in human, monkey, dog, rat and mouse hepatocytes.
Chen WW; Qin GY; Zhang T; Feng WY
Drug Metab Lett; 2012 Jun; 6(2):73-93. PubMed ID: 22594564
[TBL] [Abstract][Full Text] [Related]
5. Metabolism and disposition of [(14)C]tivantinib after oral administration to humans, dogs and rats.
Murai T; Takakusa H; Nakai D; Kamiyama E; Taira T; Kimura T; Jimbo T; Bathala M; Pickersgill F; Zahir H; Tokui T; Savage RE; Ashwell MA; Izumi T
Xenobiotica; 2014 Nov; 44(11):996-1008. PubMed ID: 24911380
[TBL] [Abstract][Full Text] [Related]
6. Pharmacokinetics, disposition and lipid-modulating activity of 5-{2-[4-(3,4-difluorophenoxy)-phenyl]-ethylsulfamoyl}-2-methyl-benzoic acid, a potent and subtype-selective peroxisome proliferator-activated receptor alpha agonist in preclinical species and human.
Frederick KS; Maurer TS; Kalgutkar AS; Royer LJ; Francone OL; Winter SM; Terra SG; Chen D; Gao X
Xenobiotica; 2009 Oct; 39(10):766-81. PubMed ID: 19622022
[TBL] [Abstract][Full Text] [Related]
7. The Nonclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of SPH3127, a Novel Direct Renin Inhibitor.
Zhang L; Mao Y; Gao Z; Chen X; Li X; Liu Y; Xia G
Eur J Drug Metab Pharmacokinet; 2020 Feb; 45(1):15-26. PubMed ID: 31494843
[TBL] [Abstract][Full Text] [Related]
8. Recent developments in naturally derived antimalarials: cryptolepine analogues.
Wright CW
J Pharm Pharmacol; 2007 Jun; 59(6):899-904. PubMed ID: 17637183
[TBL] [Abstract][Full Text] [Related]
9. Anti-inflammatory properties of cryptolepine.
Olajide OA; Ajayi AM; Wright CW
Phytother Res; 2009 Oct; 23(10):1421-5. PubMed ID: 19288476
[TBL] [Abstract][Full Text] [Related]
10. In vitro and in vivo metabolism of verproside in rats.
Kim MG; Hwang DK; Jeong HU; Ji HY; Oh SR; Lee Y; Yoo JS; Shin DH; Lee HS
Molecules; 2012 Oct; 17(10):11990-2002. PubMed ID: 23085650
[TBL] [Abstract][Full Text] [Related]
11. Pharmacokinetics of the antimalarial drug, AQ-13, in rats and cynomolgus macaques.
Ramanathan-Girish S; Catz P; Creek MR; Wu B; Thomas D; Krogstad DJ; De D; Mirsalis JC; Green CE
Int J Toxicol; 2004; 23(3):179-89. PubMed ID: 15204721
[TBL] [Abstract][Full Text] [Related]
12. Metabolism of [2-14C]p-hydroxyphenyl acetic acid in rat, monkey and human hepatocytes and in bile-duct cannulated rats.
Zhou L; Liu-Kreyche P; Iyer RA
Xenobiotica; 2011 Apr; 41(4):312-9. PubMed ID: 21143006
[TBL] [Abstract][Full Text] [Related]
13. Detection and characterization of the metabolites of rutaecarpine in rats based on ultra-high-performance liquid chromatography with linear ion trap-Orbitrap mass spectrometer.
Cai W; Guan Y; Zhou Y; Wang Y; Ji H; Liu Z
Pharm Biol; 2017 Dec; 55(1):294-298. PubMed ID: 27927077
[TBL] [Abstract][Full Text] [Related]
14. Metabolite identification of the antimalarial piperaquine in vivo using liquid chromatography-high-resolution mass spectrometry in combination with multiple data-mining tools in tandem.
Yang A; Zang M; Liu H; Fan P; Xing J
Biomed Chromatogr; 2016 Aug; 30(8):1324-30. PubMed ID: 26821381
[TBL] [Abstract][Full Text] [Related]
15. Pharmacokinetics, metabolism, and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in rats and rhesus monkeys.
Tan EY; Hartmann G; Chen Q; Pereira A; Bradley S; Doss G; Zhang AS; Ho JZ; Braun MP; Dean DC; Tang W; Kumar S
Drug Metab Dispos; 2010 Mar; 38(3):459-73. PubMed ID: 20016052
[TBL] [Abstract][Full Text] [Related]
16. Cryptolepis sanguinolenta: antimuscarinic properties of cryptolepine and the alkaloid fraction at M1, M2 and M3 receptors.
Rauwald HW; Kober M; Mutschler E; Lambrecht G
Planta Med; 1992 Dec; 58(6):486-8. PubMed ID: 1484884
[TBL] [Abstract][Full Text] [Related]
17. Identification of novel metabolic pathways of pioglitazone in hepatocytes: N-glucuronidation of thiazolidinedione ring and sequential ring-opening pathway.
Uchiyama M; Fischer T; Mueller J; Oguchi M; Yamamura N; Koda H; Iwabuchi H; Izumi T
Drug Metab Dispos; 2010 Jun; 38(6):946-56. PubMed ID: 20185540
[TBL] [Abstract][Full Text] [Related]
18. Ethnobotanical-directed discovery of the antihyperglycemic properties of cryptolepine: its isolation from Cryptolepis sanguinolenta, synthesis, and in vitro and in vivo activities.
Bierer DE; Fort DM; Mendez CD; Luo J; Imbach PA; Dubenko LG; Jolad SD; Gerber RE; Litvak J; Lu Q; Zhang P; Reed MJ; Waldeck N; Bruening RC; Noamesi BK; Hector RF; Carlson TJ; King SR
J Med Chem; 1998 Mar; 41(6):894-901. PubMed ID: 9526563
[TBL] [Abstract][Full Text] [Related]
19. In vitro and in vivo metabolism of a selective δ-opioid receptor.
Guo J; Gu C; Zhou D; Elmore CS; Bui KH; Grimm SW
Drug Metab Dispos; 2011 Oct; 39(10):1883-94. PubMed ID: 21752944
[TBL] [Abstract][Full Text] [Related]
20. Metabolism, pharmacokinetics, and excretion of a cholesteryl ester transfer protein inhibitor, torcetrapib, in rats, monkeys, and mice: characterization of unusual and novel metabolites by high-resolution liquid chromatography-tandem mass spectrometry and 1H nuclear magnetic resonance.
Prakash C; Chen W; Rossulek M; Johnson K; Zhang C; O'Connell T; Potchoiba M; Dalvie D
Drug Metab Dispos; 2008 Oct; 36(10):2064-79. PubMed ID: 18653742
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
