264 related articles for article (PubMed ID: 29276033)
1. Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor.
Harvey EP; Seo HS; Guerra RM; Bird GH; Dhe-Paganon S; Walensky LD
Structure; 2018 Jan; 26(1):153-160.e4. PubMed ID: 29276033
[TBL] [Abstract][Full Text] [Related]
2. Relationship between helix stability and binding affinities: molecular dynamics simulations of Bfl-1/A1-binding pro-apoptotic BH3 peptide helices in explicit solvent.
Modi V; Lama D; Sankararamakrishnan R
J Biomol Struct Dyn; 2013; 31(1):65-77. PubMed ID: 22803956
[TBL] [Abstract][Full Text] [Related]
3. Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.
Frappier V; Jenson JM; Zhou J; Grigoryan G; Keating AE
Structure; 2019 Apr; 27(4):606-617.e5. PubMed ID: 30773399
[TBL] [Abstract][Full Text] [Related]
4. Binding modes of Bcl-2 homology 3 (BH3) peptides with anti-apoptotic protein A1 and redesign of peptide inhibitors: a computational study.
Chen Y; Wang J; Zhang J; Wang W
J Biomol Struct Dyn; 2018 Nov; 36(15):3967-3977. PubMed ID: 29137527
[TBL] [Abstract][Full Text] [Related]
5. Selective Covalent Targeting of Anti-Apoptotic BFL-1 by Cysteine-Reactive Stapled Peptide Inhibitors.
Huhn AJ; Guerra RM; Harvey EP; Bird GH; Walensky LD
Cell Chem Biol; 2016 Sep; 23(9):1123-1134. PubMed ID: 27617850
[TBL] [Abstract][Full Text] [Related]
6. Bh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysis.
Rajan S; Choi M; Baek K; Yoon HS
Proteins; 2015 Jul; 83(7):1262-72. PubMed ID: 25907960
[TBL] [Abstract][Full Text] [Related]
7. Precision Targeting of BFL-1/A1 and an ATM Co-dependency in Human Cancer.
Guerra RM; Bird GH; Harvey EP; Dharia NV; Korshavn KJ; Prew MS; Stegmaier K; Walensky LD
Cell Rep; 2018 Sep; 24(13):3393-3403.e5. PubMed ID: 30257201
[TBL] [Abstract][Full Text] [Related]
8. A redox switch regulates the structure and function of anti-apoptotic BFL-1.
Korshavn KJ; Wales TE; Bird GH; Engen JR; Walensky LD
Nat Struct Mol Biol; 2020 Sep; 27(9):781-789. PubMed ID: 32661419
[TBL] [Abstract][Full Text] [Related]
9. hBfl-1/hNOXA Interaction Studies Provide New Insights on the Role of Bfl-1 in Cancer Cell Resistance and for the Design of Novel Anticancer Agents.
Barile E; Marconi GD; De SK; Baggio C; Gambini L; Salem AF; Kashyap MK; Castro JE; Kipps TJ; Pellecchia M
ACS Chem Biol; 2017 Feb; 12(2):444-455. PubMed ID: 28026162
[TBL] [Abstract][Full Text] [Related]
10. Selective Covalent Targeting of Anti-apoptotic BFL-1 by a Sulfonium-Tethered Peptide.
Liu N; Wang D; Lian C; Zhao R; Tu L; Zhang Y; Liu J; Zhu H; Yu M; Wan C; Li D; Li S; Yin F; Li Z
Chembiochem; 2021 Jan; 22(2):340-344. PubMed ID: 32790056
[TBL] [Abstract][Full Text] [Related]
11. A comparison of two strategies for affinity maturation of a BH3 peptide toward pro-survival Bcl-2 proteins.
Zhang S; Long A; Link AJ
ACS Synth Biol; 2012 Mar; 1(3):89-98. PubMed ID: 23651073
[TBL] [Abstract][Full Text] [Related]
12. Completing the family portrait of the anti-apoptotic Bcl-2 proteins: crystal structure of human Bfl-1 in complex with Bim.
Herman MD; Nyman T; Welin M; Lehtiö L; Flodin S; Trésaugues L; Kotenyova T; Flores A; Nordlund P
FEBS Lett; 2008 Oct; 582(25-26):3590-4. PubMed ID: 18812174
[TBL] [Abstract][Full Text] [Related]
13. Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes.
Fire E; Gullá SV; Grant RA; Keating AE
Protein Sci; 2010 Mar; 19(3):507-19. PubMed ID: 20066663
[TBL] [Abstract][Full Text] [Related]
14. Molecular dynamics simulations of pro-apoptotic BH3 peptide helices in aqueous medium: relationship between helix stability and their binding affinities to the anti-apoptotic protein Bcl-X(L).
Lama D; Sankararamakrishnan R
J Comput Aided Mol Des; 2011 May; 25(5):413-26. PubMed ID: 21523491
[TBL] [Abstract][Full Text] [Related]
15. Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function.
Chen L; Willis SN; Wei A; Smith BJ; Fletcher JI; Hinds MG; Colman PM; Day CL; Adams JM; Huang DC
Mol Cell; 2005 Feb; 17(3):393-403. PubMed ID: 15694340
[TBL] [Abstract][Full Text] [Related]
16. Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering.
Harvey EP; Hauseman ZJ; Cohen DT; Rettenmaier TJ; Lee S; Huhn AJ; Wales TE; Seo HS; Luccarelli J; Newman CE; Guerra RM; Bird GH; Dhe-Paganon S; Engen JR; Wells JA; Walensky LD
Cell Chem Biol; 2020 Jun; 27(6):647-656.e6. PubMed ID: 32413285
[TBL] [Abstract][Full Text] [Related]
17. Anti-apoptotic Bcl-XL protein in complex with BH3 peptides of pro-apoptotic Bak, Bad, and Bim proteins: comparative molecular dynamics simulations.
Lama D; Sankararamakrishnan R
Proteins; 2008 Nov; 73(2):492-514. PubMed ID: 18452209
[TBL] [Abstract][Full Text] [Related]
18. Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1.
Jenson JM; Ryan JA; Grant RA; Letai A; Keating AE
Elife; 2017 Jun; 6():. PubMed ID: 28594323
[TBL] [Abstract][Full Text] [Related]
19. Design, Synthesis, and Structural Characterization of Lysine Covalent BH3 Peptides Targeting Mcl-1.
Gambini L; Udompholkul P; Baggio C; Muralidharan A; Kenjić N; Assar Z; Perry JJP; Pellecchia M
J Med Chem; 2021 Apr; 64(8):4903-4912. PubMed ID: 33797903
[TBL] [Abstract][Full Text] [Related]
20. Conformational changes in Bcl-2 pro-survival proteins determine their capacity to bind ligands.
Lee EF; Czabotar PE; Yang H; Sleebs BE; Lessene G; Colman PM; Smith BJ; Fairlie WD
J Biol Chem; 2009 Oct; 284(44):30508-17. PubMed ID: 19726685
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]