These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 29277460)

  • 1. Aconitum alkaloids, the major components of Aconitum species, affect expression of multidrug resistance-associated protein 2 and breast cancer resistance protein by activating the Nrf2-mediated signalling pathway.
    Wu JJ; Zhu YF; Guo ZZ; Lou YM; He SG; Guan Y; Zhu LJ; Liu ZQ; Lu LL; Liu L
    Phytomedicine; 2018 May; 44():87-97. PubMed ID: 29277460
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Multidrug resistance-associated protein 2 is involved in the efflux of Aconitum alkaloids determined by MRP2-MDCKII cells.
    Dai P; Zhu L; Yang X; Zhao M; Shi J; Wang Y; Lu L; Liu Z
    Life Sci; 2015 Apr; 127():66-72. PubMed ID: 25744397
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of efflux transporters on the transport of highly toxic aconitine, mesaconitine, hypaconitine, and their hydrolysates, as determined in cultured Caco-2 and transfected MDCKII cells.
    Ye L; Yang X; Yang Z; Gao S; Yin T; Liu W; Wang F; Hu M; Liu Z
    Toxicol Lett; 2013 Feb; 216(2-3):86-99. PubMed ID: 23200901
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Astragali radix and its main bioactive compounds activate the Nrf2-mediated signaling pathway to induce P-glycoprotein and breast cancer resistance protein.
    Lou Y; Guo Z; Zhu Y; Zhang G; Wang Y; Qi X; Lu L; Liu Z; Wu J
    J Ethnopharmacol; 2019 Jan; 228():82-91. PubMed ID: 30243825
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Spica prunellae and its marker compound rosmarinic acid induced the expression of efflux transporters through activation of Nrf2-mediated signaling pathway in HepG2 cells.
    Wu J; Zhu Y; Li F; Zhang G; Shi J; Ou R; Tong Y; Liu Y; Liu L; Lu L; Liu Z
    J Ethnopharmacol; 2016 Dec; 193():1-11. PubMed ID: 27422165
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Induction of P-glycoprotein expression and activity by Aconitum alkaloids: Implication for clinical drug-drug interactions.
    Wu J; Lin N; Li F; Zhang G; He S; Zhu Y; Ou R; Li N; Liu S; Feng L; Liu L; Liu Z; Lu L
    Sci Rep; 2016 May; 6():25343. PubMed ID: 27139035
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential selectivity of efflux transporter inhibitors in Caco-2 and MDCK-MDR1 monolayers: a strategy to assess the interaction of a new chemical entity with P-gp, BCRP, and MRP2.
    Mease K; Sane R; Podila L; Taub ME
    J Pharm Sci; 2012 May; 101(5):1888-97. PubMed ID: 22359351
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A new mechanism for increasing the oral bioavailability of scutellarin with Cremophor EL: Activation of MRP3 with concurrent inhibition of MRP2 and BCRP.
    Xiao L; Yi T; Chen M; Lam CW; Zhou H
    Eur J Pharm Sci; 2016 Oct; 93():456-67. PubMed ID: 27586020
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Small intestinal efflux mediated by MRP2 and BCRP shifts sulfasalazine intestinal permeability from high to low, enabling its colonic targeting.
    Dahan A; Amidon GL
    Am J Physiol Gastrointest Liver Physiol; 2009 Aug; 297(2):G371-7. PubMed ID: 19541926
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mdr1a, Bcrp and Mrp2 regulate the efficacy and toxicity of mesaconitine and hypaconitine by altering their tissue accumulation and in vivo residence.
    Li X; Ou X; Luo G; Ou X; Xie Y; Ying M; Qu W; Zuo H; Qi X; Wang Y; Liu Z; Zhu L
    Toxicol Appl Pharmacol; 2020 Dec; 409():115332. PubMed ID: 33171190
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Zinc finger nuclease-mediated gene knockout results in loss of transport activity for P-glycoprotein, BCRP, and MRP2 in Caco-2 cells.
    Sampson KE; Brinker A; Pratt J; Venkatraman N; Xiao Y; Blasberg J; Steiner T; Bourner M; Thompson DC
    Drug Metab Dispos; 2015 Feb; 43(2):199-207. PubMed ID: 25388687
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Aristolochic acid I is a substrate of BCRP but not P-glycoprotein or MRP2.
    Ma L; Qin Y; Shen Z; Bi H; Hu H; Huang M; Zhou H; Yu L; Jiang H; Zeng S
    J Ethnopharmacol; 2015 Aug; 172():430-5. PubMed ID: 26183576
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A systematic review of pharmacokinetic studies on herbal drug Fuzi: Implications for Fuzi as personalized medicine.
    Wu JJ; Guo ZZ; Zhu YF; Huang ZJ; Gong X; Li YH; Son WJ; Li XY; Lou YM; Zhu LJ; Lu LL; Liu ZQ; Liu L
    Phytomedicine; 2018 May; 44():187-203. PubMed ID: 29526584
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity.
    Arias A; Rigalli JP; Villanueva SS; Ruiz ML; Luquita MG; Perdomo VG; Vore M; Catania VA; Mottino AD
    Toxicology; 2014 Jun; 320():46-55. PubMed ID: 24685904
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Roles of P-glycoprotein, Bcrp, and Mrp2 in biliary excretion of spiramycin in mice.
    Tian X; Li J; Zamek-Gliszczynski MJ; Bridges AS; Zhang P; Patel NJ; Raub TJ; Pollack GM; Brouwer KL
    Antimicrob Agents Chemother; 2007 Sep; 51(9):3230-4. PubMed ID: 17576841
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of the antiretroviral drug 2'-deoxy-2'-β-fluoro-4'-azidocytidine (FNC) on P-gp, MRP2 and BCRP expressions and functions.
    Liu Y; Wang Y; Peng Y; Liu B; Ma F; Jiang J; Wang Q; Chang J
    Pharmazie; 2018 Sep; 73(9):503-507. PubMed ID: 30223932
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cisplatin-induced chemoresistance in colon cancer cells involves FXR-dependent and FXR-independent up-regulation of ABC proteins.
    Herraez E; Gonzalez-Sanchez E; Vaquero J; Romero MR; Serrano MA; Marin JJ; Briz O
    Mol Pharm; 2012 Sep; 9(9):2565-76. PubMed ID: 22800197
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Liver X receptor regulates expression of MRP2 but not that of MDR1 and BCRP in the liver.
    Chisaki I; Kobayashi M; Itagaki S; Hirano T; Iseki K
    Biochim Biophys Acta; 2009 Nov; 1788(11):2396-403. PubMed ID: 19728987
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of P-glycoprotein by Bajijiasu in vitro and in vivo by activating the Nrf2-mediated signalling pathway.
    Yang X; Hu G; Lv L; Liu T; Qi L; Huang G; You D; Zhao J
    Pharm Biol; 2019 Dec; 57(1):184-192. PubMed ID: 30929555
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of efflux transport of the PDE5 inhibitors, vardenafil and sildenafil.
    Choi MK; Song IS
    J Pharm Pharmacol; 2012 Aug; 64(8):1074-83. PubMed ID: 22775210
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.