These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

641 related articles for article (PubMed ID: 29282029)

  • 1. Docosahexaenoic acid reduces sterol regulatory element binding protein-1 and fatty acid synthase expression and inhibits cell proliferation by inhibiting pAkt signaling in a human breast cancer MCF-7 cell line.
    Huang LH; Chung HY; Su HM
    BMC Cancer; 2017 Dec; 17(1):890. PubMed ID: 29282029
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prolonged high-glucose exposure decreased SREBP-1/FASN/ACC in Schwann cells of diabetic mice via blocking PI3K/Akt pathway.
    Zhu L; Du W; Liu Y; Cheng M; Wang X; Zhang C; Lv X; Li F; Zhao S; Hao J
    J Cell Biochem; 2019 Apr; 120(4):5777-5789. PubMed ID: 30362584
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Docosahexaenoic acid inhibits insulin-induced activation of sterol regulatory-element binding protein 1 and cyclooxygenase-2 expression through upregulation of SIRT1 in human colon epithelial cells.
    Song NY; Na HK; Baek JH; Surh YJ
    Biochem Pharmacol; 2014 Nov; 92(1):142-8. PubMed ID: 25199460
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Docosahexaenoic acid inhibits proteolytic processing of sterol regulatory element-binding protein-1c (SREBP-1c) via activation of AMP-activated kinase.
    Deng X; Dong Q; Bridges D; Raghow R; Park EA; Elam MB
    Biochim Biophys Acta; 2015 Dec; 1851(12):1521-9. PubMed ID: 26327595
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Down-regulation of PKM2 decreases FASN expression in bladder cancer cells through AKT/mTOR/SREBP-1c axis.
    Tao T; Su Q; Xu S; Deng J; Zhou S; Zhuang Y; Huang Y; He C; He S; Peng M; Hocher B; Yang X
    J Cell Physiol; 2019 Mar; 234(3):3088-3104. PubMed ID: 30221356
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Histone modifications in FASN modulated by sterol regulatory element-binding protein 1c and carbohydrate responsive-element binding protein under insulin stimulation are related to NAFLD.
    Du X; Cai C; Yao J; Zhou Y; Yu H; Shen W
    Biochem Biophys Res Commun; 2017 Jan; 483(1):409-417. PubMed ID: 28027934
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selective regulation of UGT1A1 and SREBP-1c mRNA expression by docosahexaenoic, eicosapentaenoic, and arachidonic acids.
    Caputo M; Zirpoli H; Torino G; Tecce MF
    J Cell Physiol; 2011 Jan; 226(1):187-93. PubMed ID: 20648548
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Docosahexaenoic acid increases the expression of oxidative stress-induced growth inhibitor 1 through the PI3K/Akt/Nrf2 signaling pathway in breast cancer cells.
    Tsai CH; Shen YC; Chen HW; Liu KL; Chang JW; Chen PY; Lin CY; Yao HT; Li CC
    Food Chem Toxicol; 2017 Oct; 108(Pt A):276-288. PubMed ID: 28807874
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Long chain n-3 polyunsaturated fatty acids increase the efficacy of docetaxel in mammary cancer cells by downregulating Akt and PKCε/δ-induced ERK pathways.
    Chauvin L; Goupille C; Blanc C; Pinault M; Domingo I; Guimaraes C; Bougnoux P; Chevalier S; Mahéo K
    Biochim Biophys Acta; 2016 Apr; 1861(4):380-90. PubMed ID: 26821209
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Docosapentaenoic acid (22:5n-3) down-regulates the expression of genes involved in fat synthesis in liver cells.
    Kaur G; Sinclair AJ; Cameron-Smith D; Barr DP; Molero-Navajas JC; Konstantopoulos N
    Prostaglandins Leukot Essent Fatty Acids; 2011; 85(3-4):155-61. PubMed ID: 21807486
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis.
    Menendez JA; Ropero S; Mehmi I; Atlas E; Colomer R; Lupu R
    Int J Oncol; 2004 Jun; 24(6):1369-83. PubMed ID: 15138577
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Leucine deprivation inhibits proliferation and induces apoptosis of human breast cancer cells via fatty acid synthase.
    Xiao F; Wang C; Yin H; Yu J; Chen S; Fang J; Guo F
    Oncotarget; 2016 Sep; 7(39):63679-63689. PubMed ID: 27579768
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells.
    Yoon S; Lee MY; Park SW; Moon JS; Koh YK; Ahn YH; Park BW; Kim KS
    J Biol Chem; 2007 Sep; 282(36):26122-31. PubMed ID: 17631500
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Clinical importance of FASN in relation to HIF-1α and SREBP-1c in gastric adenocarcinoma.
    Ezzeddini R; Taghikhani M; Somi MH; Samadi N; Rasaee MJ
    Life Sci; 2019 May; 224():169-176. PubMed ID: 30914315
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of fatty acid synthase suppresses the malignant phenotype of colorectal cancer cells by down-regulating energy metabolism and mTOR signaling pathway.
    Chang L; Wu P; Senthilkumar R; Tian X; Liu H; Shen X; Tao Z; Huang P
    J Cancer Res Clin Oncol; 2016 Jan; 142(1):59-72. PubMed ID: 26109148
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 3,5-Diiodo-l-thyronine induces SREBP-1 proteolytic cleavage block and apoptosis in human hepatoma (Hepg2) cells.
    Rochira A; Damiano F; Marsigliante S; Gnoni GV; Siculella L
    Biochim Biophys Acta; 2013 Dec; 1831(12):1679-89. PubMed ID: 23948263
    [TBL] [Abstract][Full Text] [Related]  

  • 17. α-linolenic acid and docosahexaenoic acid, alone and combined with trastuzumab, reduce HER2-overexpressing breast cancer cell growth but differentially regulate HER2 signaling pathways.
    Mason JK; Klaire S; Kharotia S; Wiggins AK; Thompson LU
    Lipids Health Dis; 2015 Aug; 14():91. PubMed ID: 26282560
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sterol regulatory element-binding protein-1/fatty acid synthase involvement in proliferation inhibition and apoptosis promotion induced by progesterone in endometrial cancer.
    Qiu C; Dongol S; Lv QT; Gao X; Jiang J
    Int J Gynecol Cancer; 2013 Nov; 23(9):1629-34. PubMed ID: 24105476
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Kr-pok increases FASN expression by modulating the DNA binding of SREBP-1c and Sp1 at the proximal promoter.
    Jeon BN; Kim YS; Choi WI; Koh DI; Kim MK; Yoon JH; Kim MY; Hur B; Paik PD; Hur MW
    J Lipid Res; 2012 Apr; 53(4):755-66. PubMed ID: 22331133
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ellagic acid ameliorates AKT-driven hepatic steatosis in mice by suppressing de novo lipogenesis via the AKT/SREBP-1/FASN pathway.
    Zhang C; Hu J; Sheng L; Yuan M; Wu Y; Chen L; Wang G; Qiu Z
    Food Funct; 2019 Jun; 10(6):3410-3420. PubMed ID: 31123744
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.