69 related articles for article (PubMed ID: 29282301)
21. Gossypol has anti-cancer effects by dual-targeting MDM2 and VEGF in human breast cancer.
Xiong J; Li J; Yang Q; Wang J; Su T; Zhou S
Breast Cancer Res; 2017 Mar; 19(1):27. PubMed ID: 28274247
[TBL] [Abstract][Full Text] [Related]
22. 2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol inhibits MDM2 and induces apoptosis in breast cancer cells through a p53-independent pathway.
Xu J; Han M; Shen J; Guan Q; Bai Z; Lang B; Zhang H; Li Z; Zuo D; Zhang W; Wu Y
Cancer Lett; 2016 Dec; 383(1):9-17. PubMed ID: 27693458
[TBL] [Abstract][Full Text] [Related]
23. Upregulation of p53 through induction of MDM2 degradation: improved potency through the introduction of an alkylketone sidechain on the anthraquinone core.
Tripathi R; Anifowose A; Lu W; Yang X; Wang B
J Enzyme Inhib Med Chem; 2022 Dec; 37(1):2370-2381. PubMed ID: 36043494
[TBL] [Abstract][Full Text] [Related]
24. Preclinical Efficacy of the MDM2 Inhibitor RG7112 in MDM2-Amplified and TP53 Wild-type Glioblastomas.
Verreault M; Schmitt C; Goldwirt L; Pelton K; Haidar S; Levasseur C; Guehennec J; Knoff D; Labussière M; Marie Y; Ligon AH; Mokhtari K; Hoang-Xuan K; Sanson M; Alexander BM; Wen PY; Delattre JY; Ligon KL; Idbaih A
Clin Cancer Res; 2016 Mar; 22(5):1185-96. PubMed ID: 26482041
[TBL] [Abstract][Full Text] [Related]
25. Results of the Phase I Trial of RG7112, a Small-Molecule MDM2 Antagonist in Leukemia.
Andreeff M; Kelly KR; Yee K; Assouline S; Strair R; Popplewell L; Bowen D; Martinelli G; Drummond MW; Vyas P; Kirschbaum M; Iyer SP; Ruvolo V; González GM; Huang X; Chen G; Graves B; Blotner S; Bridge P; Jukofsky L; Middleton S; Reckner M; Rueger R; Zhi J; Nichols G; Kojima K
Clin Cancer Res; 2016 Feb; 22(4):868-76. PubMed ID: 26459177
[TBL] [Abstract][Full Text] [Related]
26. Rhein Elicits In Vitro Cytotoxicity in Primary Human Liver HL-7702 Cells by Inducing Apoptosis through Mitochondria-Mediated Pathway.
Bounda GA; Zhou W; Wang DD; Yu F
Evid Based Complement Alternat Med; 2015; 2015():329831. PubMed ID: 26221172
[TBL] [Abstract][Full Text] [Related]
27. Rhein induces apoptosis in human breast cancer cells.
Chang CY; Chan HL; Lin HY; Way TD; Kao MC; Song MZ; Lin YJ; Lin CW
Evid Based Complement Alternat Med; 2012; 2012():952504. PubMed ID: 22007260
[TBL] [Abstract][Full Text] [Related]
28. Novel rhein analogues as potential anticancer agents.
Yang X; Sun G; Yang C; Wang B
ChemMedChem; 2011 Dec; 6(12):2294-301. PubMed ID: 21954017
[TBL] [Abstract][Full Text] [Related]
29. MdmX protein is essential for Mdm2 protein-mediated p53 polyubiquitination.
Wang X; Wang J; Jiang X
J Biol Chem; 2011 Jul; 286(27):23725-34. PubMed ID: 21572037
[TBL] [Abstract][Full Text] [Related]
30. Degradation of MDM2 by the interaction between berberine and DAXX leads to potent apoptosis in MDM2-overexpressing cancer cells.
Zhang X; Gu L; Li J; Shah N; He J; Yang L; Hu Q; Zhou M
Cancer Res; 2010 Dec; 70(23):9895-904. PubMed ID: 20935220
[TBL] [Abstract][Full Text] [Related]
31. The p53 orchestra: Mdm2 and Mdmx set the tone.
Wade M; Wang YV; Wahl GM
Trends Cell Biol; 2010 May; 20(5):299-309. PubMed ID: 20172729
[TBL] [Abstract][Full Text] [Related]
32. Doxorubicin: the good, the bad and the ugly effect.
Carvalho C; Santos RX; Cardoso S; Correia S; Oliveira PJ; Santos MS; Moreira PI
Curr Med Chem; 2009; 16(25):3267-85. PubMed ID: 19548866
[TBL] [Abstract][Full Text] [Related]
33. Anti-proliferative effect of rhein, an anthraquinone isolated from Cassia species, on Caco-2 human adenocarcinoma cells.
Aviello G; Rowland I; Gill CI; Acquaviva AM; Capasso F; McCann M; Capasso R; Izzo AA; Borrelli F
J Cell Mol Med; 2010 Jul; 14(7):2006-14. PubMed ID: 19538468
[TBL] [Abstract][Full Text] [Related]
34. Rhein induces apoptosis and cell cycle arrest in human hepatocellular carcinoma BEL-7402 cells.
Shi P; Huang Z; Chen G
Am J Chin Med; 2008; 36(4):805-13. PubMed ID: 18711776
[TBL] [Abstract][Full Text] [Related]
35. Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans.
Linke K; Mace PD; Smith CA; Vaux DL; Silke J; Day CL
Cell Death Differ; 2008 May; 15(5):841-8. PubMed ID: 18219319
[TBL] [Abstract][Full Text] [Related]
36. MDM2 chaperones the p53 tumor suppressor.
Wawrzynow B; Zylicz A; Wallace M; Hupp T; Zylicz M
J Biol Chem; 2007 Nov; 282(45):32603-12. PubMed ID: 17848574
[TBL] [Abstract][Full Text] [Related]
37. Curcumin, a dietary component, has anticancer, chemosensitization, and radiosensitization effects by down-regulating the MDM2 oncogene through the PI3K/mTOR/ETS2 pathway.
Li M; Zhang Z; Hill DL; Wang H; Zhang R
Cancer Res; 2007 Mar; 67(5):1988-96. PubMed ID: 17332326
[TBL] [Abstract][Full Text] [Related]
38. Anti-cancer properties of anthraquinones from rhubarb.
Huang Q; Lu G; Shen HM; Chung MC; Ong CN
Med Res Rev; 2007 Sep; 27(5):609-30. PubMed ID: 17022020
[TBL] [Abstract][Full Text] [Related]
39. Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo.
Francoz S; Froment P; Bogaerts S; De Clercq S; Maetens M; Doumont G; Bellefroid E; Marine JC
Proc Natl Acad Sci U S A; 2006 Feb; 103(9):3232-7. PubMed ID: 16492744
[TBL] [Abstract][Full Text] [Related]
40. MDM2 and human malignancies: expression, clinical pathology, prognostic markers, and implications for chemotherapy.
Rayburn E; Zhang R; He J; Wang H
Curr Cancer Drug Targets; 2005 Feb; 5(1):27-41. PubMed ID: 15720187
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
