BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

249 related articles for article (PubMed ID: 29282338)

  • 1. Unaffected mosaic
    McGoldrick P; Zhang M; van Blitterswijk M; Sato C; Moreno D; Xiao S; Zhang AB; McKeever PM; Weichert A; Schneider R; Keith J; Petrucelli L; Rademakers R; Zinman L; Robertson J; Rogaeva E
    Neurology; 2018 Jan; 90(4):e323-e331. PubMed ID: 29282338
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Jump from pre-mutation to pathologic expansion in C9orf72.
    Xi Z; van Blitterswijk M; Zhang M; McGoldrick P; McLean JR; Yunusova Y; Knock E; Moreno D; Sato C; McKeever PM; Schneider R; Keith J; Petrescu N; Fraser P; Tartaglia MC; Baker MC; Graff-Radford NR; Boylan KB; Dickson DW; Mackenzie IR; Rademakers R; Robertson J; Zinman L; Rogaeva E
    Am J Hum Genet; 2015 Jun; 96(6):962-70. PubMed ID: 26004200
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration.
    Gomez-Deza J; Lee YB; Troakes C; Nolan M; Al-Sarraj S; Gallo JM; Shaw CE
    Acta Neuropathol Commun; 2015 Jun; 3():38. PubMed ID: 26108573
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of C9orf72 hexanucleotide repeat expansion leads to formation of RNA foci and dipeptide repeat proteins but does not influence autophagy or proteasomal function in neuronal cells.
    Leskelä S; Huber N; Hoffmann D; Rostalski H; Remes AM; Takalo M; Hiltunen M; Haapasalo A
    Biochim Biophys Acta Mol Cell Res; 2021 Jun; 1868(7):119021. PubMed ID: 33775797
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An ALS case with 38 (G4C2)-repeats in the C9orf72 gene shows TDP-43 and sparse dipeptide repeat protein pathology.
    Dedeene L; Van Schoor E; Race V; Moisse M; Vandenberghe R; Poesen K; Van Damme P; Thal DR
    Acta Neuropathol; 2019 May; 137(5):855-858. PubMed ID: 30919029
    [No Abstract]   [Full Text] [Related]  

  • 6. Drosha inclusions are new components of dipeptide-repeat protein aggregates in FTLD-TDP and ALS C9orf72 expansion cases.
    Porta S; Kwong LK; Trojanowski JQ; Lee VM
    J Neuropathol Exp Neurol; 2015 Apr; 74(4):380-7. PubMed ID: 25756586
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Circadian sleep/wake-associated cells show dipeptide repeat protein aggregates in C9orf72-related ALS and FTLD cases.
    Dedeene L; Van Schoor E; Vandenberghe R; Van Damme P; Poesen K; Thal DR
    Acta Neuropathol Commun; 2019 Dec; 7(1):189. PubMed ID: 31791419
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy.
    Chew J; Cook C; Gendron TF; Jansen-West K; Del Rosso G; Daughrity LM; Castanedes-Casey M; Kurti A; Stankowski JN; Disney MD; Rothstein JD; Dickson DW; Fryer JD; Zhang YJ; Petrucelli L
    Mol Neurodegener; 2019 Feb; 14(1):9. PubMed ID: 30767771
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions.
    Cooper-Knock J; Walsh MJ; Higginbottom A; Robin Highley J; Dickman MJ; Edbauer D; Ince PG; Wharton SB; Wilson SA; Kirby J; Hautbergue GM; Shaw PJ
    Brain; 2014 Jul; 137(Pt 7):2040-51. PubMed ID: 24866055
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders.
    Boivin M; Pfister V; Gaucherot A; Ruffenach F; Negroni L; Sellier C; Charlet-Berguerand N
    EMBO J; 2020 Feb; 39(4):e100574. PubMed ID: 31930538
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The C9orf72 repeat expansion itself is methylated in ALS and FTLD patients.
    Xi Z; Zhang M; Bruni AC; Maletta RG; Colao R; Fratta P; Polke JM; Sweeney MG; Mudanohwo E; Nacmias B; Sorbi S; Tartaglia MC; Rainero I; Rubino E; Pinessi L; Galimberti D; Surace EI; McGoldrick P; McKeever P; Moreno D; Sato C; Liang Y; Keith J; Zinman L; Robertson J; Rogaeva E
    Acta Neuropathol; 2015 May; 129(5):715-27. PubMed ID: 25716178
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The C9orf72 repeat size correlates with onset age of disease, DNA methylation and transcriptional downregulation of the promoter.
    Gijselinck I; Van Mossevelde S; van der Zee J; Sieben A; Engelborghs S; De Bleecker J; Ivanoiu A; Deryck O; Edbauer D; Zhang M; Heeman B; Bäumer V; Van den Broeck M; Mattheijssens M; Peeters K; Rogaeva E; De Jonghe P; Cras P; Martin JJ; de Deyn PP; Cruts M; Van Broeckhoven C
    Mol Psychiatry; 2016 Aug; 21(8):1112-24. PubMed ID: 26481318
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The RNA exosome complex degrades expanded hexanucleotide repeat RNA in C9orf72 FTLD/ALS.
    Kawabe Y; Mori K; Yamashita T; Gotoh S; Ikeda M
    EMBO J; 2020 Oct; 39(19):e102700. PubMed ID: 32830871
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy.
    Cooper-Knock J; Higginbottom A; Stopford MJ; Highley JR; Ince PG; Wharton SB; Pickering-Brown S; Kirby J; Hautbergue GM; Shaw PJ
    Acta Neuropathol; 2015 Jul; 130(1):63-75. PubMed ID: 25943887
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G
    Czuppa M; Dhingra A; Zhou Q; Schludi C; König L; Scharf E; Farny D; Dalmia A; Täger J; Castillo-Lizardo M; Katona E; Mori K; Aumer T; Schelter F; Müller M; Carell T; Kalliokoski T; Messinger J; Rizzu P; Heutink P; Edbauer D
    Cell Rep; 2022 Jun; 39(10):110913. PubMed ID: 35675776
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stable transgenic C9orf72 zebrafish model key aspects of the ALS/FTD phenotype and reveal novel pathological features.
    Shaw MP; Higginbottom A; McGown A; Castelli LM; James E; Hautbergue GM; Shaw PJ; Ramesh TM
    Acta Neuropathol Commun; 2018 Nov; 6(1):125. PubMed ID: 30454072
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular Mechanisms of Neurodegeneration Related to
    Babić Leko M; Župunski V; Kirincich J; Smilović D; Hortobágyi T; Hof PR; Šimić G
    Behav Neurol; 2019; 2019():2909168. PubMed ID: 30774737
    [TBL] [Abstract][Full Text] [Related]  

  • 18. C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels.
    Beckers J; Tharkeshwar AK; Van Damme P
    Autophagy; 2021 Nov; 17(11):3306-3322. PubMed ID: 33632058
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Genetics of
    Gijselinck I; Cruts M; Van Broeckhoven C
    Cold Spring Harb Perspect Med; 2018 Apr; 8(4):. PubMed ID: 28130313
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The widening spectrum of C9ORF72-related disease; genotype/phenotype correlations and potential modifiers of clinical phenotype.
    Cooper-Knock J; Shaw PJ; Kirby J
    Acta Neuropathol; 2014 Mar; 127(3):333-45. PubMed ID: 24493408
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.