BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

84 related articles for article (PubMed ID: 29287690)

  • 1. Implication of STARD5 and cholesterol homeostasis disturbance in the endoplasmic reticulum stress-related response induced by pro-apoptotic aminosteroid RM-133.
    Perreault M; Maltais R; Kenmogne LC; Létourneau D; LeHoux JG; Gobeil S; Poirier D
    Pharmacol Res; 2018 Feb; 128():52-60. PubMed ID: 29287690
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Induction of endoplasmic reticulum stress by aminosteroid derivative RM-581 leads to tumor regression in PANC-1 xenograft model.
    Perreault M; Maltais R; Roy J; Picard S; Popa I; Bertrand N; Poirier D
    Invest New Drugs; 2019 Jun; 37(3):431-440. PubMed ID: 30062573
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Explorative study on the anticancer activity, selectivity and metabolic stability of related analogs of aminosteroid RM-133.
    Perreault M; Maltais R; Dutour R; Poirier D
    Steroids; 2016 Nov; 115():105-113. PubMed ID: 27553727
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Induction of Endoplasmic Reticulum Stress-Mediated Apoptosis by Aminosteroid RM-581 Efficiently Blocks the Growth of PC-3 Cancer Cells and Tumors Resistant or Not to Docetaxel.
    Maltais R; Roy J; Perreault M; Sato S; Lévesque JC; Poirier D
    Int J Mol Sci; 2021 Oct; 22(20):. PubMed ID: 34681843
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chemical synthesis, NMR analysis and evaluation on a cancer xenograft model (HL-60) of the aminosteroid derivative RM-133.
    Maltais R; Hospital A; Delhomme A; Roy J; Poirier D
    Steroids; 2014 Apr; 82():68-76. PubMed ID: 24486462
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Steroidogenic acute regulatory-related lipid transfer domain protein 5 localization and regulation in renal tubules.
    Chen YC; Meier RK; Zheng S; Khundmiri SJ; Tseng MT; Lederer ED; Epstein PN; Clark BJ
    Am J Physiol Renal Physiol; 2009 Aug; 297(2):F380-8. PubMed ID: 19474188
    [TBL] [Abstract][Full Text] [Related]  

  • 7. StarD5: an ER stress protein regulates plasma membrane and intracellular cholesterol homeostasis.
    Rodriguez-Agudo D; Malacrida L; Kakiyama G; Sparrer T; Fortes C; Maceyka M; Subler MA; Windle JJ; Gratton E; Pandak WM; Gil G
    J Lipid Res; 2019 Jun; 60(6):1087-1098. PubMed ID: 31015253
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aminosteroid RM-581 Decreases Cell Proliferation of All Breast Cancer Molecular Subtypes, Alone and in Combination with Breast Cancer Treatments.
    Burguin A; Roy J; Ouellette G; Maltais R; Bherer J; Diorio C; Poirier D; Durocher F
    J Clin Med; 2023 Jun; 12(13):. PubMed ID: 37445276
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.
    Merlot AM; Shafie NH; Yu Y; Richardson V; Jansson PJ; Sahni S; Lane DJR; Kovacevic Z; Kalinowski DS; Richardson DR
    Biochem Pharmacol; 2016 Jun; 109():27-47. PubMed ID: 27059255
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Localization of StarD5 cholesterol binding protein.
    Rodriguez-Agudo D; Ren S; Hylemon PB; Montañez R; Redford K; Natarajan R; Medina MA; Gil G; Pandak WM
    J Lipid Res; 2006 Jun; 47(6):1168-75. PubMed ID: 16534142
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ER stress increases StarD5 expression by stabilizing its mRNA and leads to relocalization of its protein from the nucleus to the membranes.
    Rodriguez-Agudo D; Calderon-Dominguez M; Medina MA; Ren S; Gil G; Pandak WM
    J Lipid Res; 2012 Dec; 53(12):2708-15. PubMed ID: 23053693
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Minor chemical modifications of the aminosteroid derivative RM-581 lead to major impact on its anticancer activity, metabolic stability and aqueous solubility.
    Maltais R; Perreault M; Roy J; Poirier D
    Eur J Med Chem; 2020 Feb; 188():111990. PubMed ID: 31893547
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Aminosteroid Derivative RM-133 Shows In Vitro and In Vivo Antitumor Activity in Human Ovarian and Pancreatic Cancers.
    Kenmogne LC; Ayan D; Roy J; Maltais R; Poirier D
    PLoS One; 2015; 10(12):e0144890. PubMed ID: 26660672
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Involvement of extrinsic and intrinsic apoptotic pathways together with endoplasmic reticulum stress in cell death induced by naphthylchalcones in a leukemic cell line: advantages of multi-target action.
    Winter E; Chiaradia LD; Silva AH; Nunes RJ; Yunes RA; Creczynski-Pasa TB
    Toxicol In Vitro; 2014 Aug; 28(5):769-77. PubMed ID: 24583196
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 4-HPR Is an Endoplasmic Reticulum Stress Aggravator and Sensitizes Breast Cancer Cells Resistant to TRAIL/Apo2L.
    Anding AL; Jones JD; Newton MA; Curley RW; Clagett-Dame M
    Anticancer Res; 2018 Aug; 38(8):4403-4416. PubMed ID: 30061204
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Deoxyrhapontigenin, a Natural Stilbene Derivative Isolated From Rheum undulatum L. Induces Endoplasmic Reticulum Stress-Mediated Apoptosis in Human Breast Cancer Cells.
    Venkatesan T; Jeong MJ; Choi YW; Park EJ; El-Desouky SK; Kim YK
    Integr Cancer Ther; 2016 Dec; 15(4):NP44-NP52. PubMed ID: 27151591
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel benzofuran derivative, ACDB, induces apoptosis of human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress.
    Su CM; Chen CY; Lu T; Sun Y; Li W; Huang YL; Tsai CH; Chang CS; Tang CH
    Oncotarget; 2016 Dec; 7(50):83530-83543. PubMed ID: 27835579
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Shikonin selectively induces apoptosis in human prostate cancer cells through the endoplasmic reticulum stress and mitochondrial apoptotic pathway.
    Gara RK; Srivastava VK; Duggal S; Bagga JK; Bhatt M; Sanyal S; Mishra DP
    J Biomed Sci; 2015 Apr; 22(1):26. PubMed ID: 25879420
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Silibinin induces mitochondrial NOX4-mediated endoplasmic reticulum stress response and its subsequent apoptosis.
    Kim SH; Kim KY; Yu SN; Seo YK; Chun SS; Yu HS; Ahn SC
    BMC Cancer; 2016 Jul; 16():452. PubMed ID: 27405931
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human StarD5, a cytosolic StAR-related lipid binding protein.
    Rodriguez-Agudo D; Ren S; Hylemon PB; Redford K; Natarajan R; Del Castillo A; Gil G; Pandak WM
    J Lipid Res; 2005 Aug; 46(8):1615-23. PubMed ID: 15897605
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.