521 related articles for article (PubMed ID: 29289881)
1. Synthesis of podophyllotoxin linked β-carboline congeners as potential anticancer agents and DNA topoisomerase II inhibitors.
Sathish M; Kavitha B; Nayak VL; Tangella Y; Ajitha A; Nekkanti S; Alarifi A; Shankaraiah N; Nagesh N; Kamal A
Eur J Med Chem; 2018 Jan; 144():557-571. PubMed ID: 29289881
[TBL] [Abstract][Full Text] [Related]
2. 4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.
Reddy VG; Bonam SR; Reddy TS; Akunuri R; Naidu VGM; Nayak VL; Bhargava SK; Kumar HMS; Srihari P; Kamal A
Eur J Med Chem; 2018 Jan; 144():595-611. PubMed ID: 29289884
[TBL] [Abstract][Full Text] [Related]
3. One-pot synthesis of podophyllotoxin-thiourea congeners by employing NH₂SO₃H/NaI: Anticancer activity, DNA topoisomerase-II inhibition, and apoptosis inducing agents.
Shankaraiah N; Kumar NP; Amula SB; Nekkanti S; Jeengar MK; Naidu VG; Reddy TS; Kamal A
Bioorg Med Chem Lett; 2015 Oct; 25(19):4239-44. PubMed ID: 26292628
[TBL] [Abstract][Full Text] [Related]
4. Development of β-carboline-benzothiazole hybrids via carboxamide formation as cytotoxic agents: DNA intercalative topoisomerase IIα inhibition and apoptosis induction.
Tokala R; Mahajan S; Kiranmai G; Sigalapalli DK; Sana S; John SE; Nagesh N; Shankaraiah N
Bioorg Chem; 2021 Jan; 106():104481. PubMed ID: 33261848
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of 4β-N-polyaromatic substituted podophyllotoxins: DNA topoisomerase inhibition, anticancer and apoptosis-inducing activities.
Kamal A; Kumar BA; Suresh P; Agrawal SK; Chashoo G; Singh SK; Saxena AK
Bioorg Med Chem; 2010 Dec; 18(24):8493-500. PubMed ID: 21074444
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and in vitro cytotoxicity evaluation of β-carboline-combretastatin carboxamides as apoptosis inducing agents: DNA intercalation and topoisomerase-II inhibition.
Jadala C; Sathish M; Reddy TS; Reddy VG; Tokala R; Bhargava SK; Shankaraiah N; Nagesh N; Kamal A
Bioorg Med Chem; 2019 Aug; 27(15):3285-3298. PubMed ID: 31227365
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis and biological evaluation of new β-carboline-bisindole compounds as DNA binding, photocleavage agents and topoisomerase I inhibitors.
Kovvuri J; Nagaraju B; Nayak VL; Akunuri R; Rao MPN; Ajitha A; Nagesh N; Kamal A
Eur J Med Chem; 2018 Jan; 143():1563-1577. PubMed ID: 29129513
[TBL] [Abstract][Full Text] [Related]
8. Design and synthesis of thiadiazolo-carboxamide bridged β-carboline-indole hybrids: DNA intercalative topo-IIα inhibition with promising antiproliferative activity.
Tokala R; Sana S; Lakshmi UJ; Sankarana P; Sigalapalli DK; Gadewal N; Kode J; Shankaraiah N
Bioorg Chem; 2020 Dec; 105():104357. PubMed ID: 33091673
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and evaluation of etoposide and podophyllotoxin analogs against topoisomerase IIα and HCT-116 cells.
Murphy MB; Kumar P; Bradley AM; Barton CE; Deweese JE; Mercer SL
Bioorg Med Chem; 2020 Nov; 28(22):115773. PubMed ID: 33035756
[TBL] [Abstract][Full Text] [Related]
10. A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation.
Zhao W; Chen L; Li HM; Wang DJ; Li DS; Chen T; Yuan ZP; Tang YJ
Bioorg Med Chem; 2014 Jun; 22(11):2998-3007. PubMed ID: 24775914
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and biological evaluation of 4β-(thiazol-2-yl)amino-4'-O-demethyl-4-deoxypodophyllotoxins as topoisomerase-II inhibitors.
Sang CY; Tian HZ; Chen Y; Liu JF; Chen SW; Hui L
Bioorg Med Chem Lett; 2018 Jan; 28(2):71-76. PubMed ID: 29248296
[TBL] [Abstract][Full Text] [Related]
12. 4β-[4'-(1-(Aryl)ureido)benzamide]podophyllotoxins as DNA topoisomerase I and IIα inhibitors and apoptosis inducing agents.
Kamal A; Suresh P; Ramaiah MJ; Srinivasa Reddy T; Kapavarapu RK; Rao BN; Imthiajali S; Lakshminarayan Reddy T; Pushpavalli SN; Shankaraiah N; Pal-Bhadra M
Bioorg Med Chem; 2013 Sep; 21(17):5198-208. PubMed ID: 23849207
[TBL] [Abstract][Full Text] [Related]
13. Design and synthesis of the novel DNA topoisomerase II inhibitors: esterification and amination substituted 4'-demethylepipodophyllotoxin derivates exhibiting anti-tumor activity by activating ATM/ATR signaling pathways.
Xiao L; Zhao W; Li HM; Wan DJ; Li DS; Chen T; Tang YJ
Eur J Med Chem; 2014 Jun; 80():267-77. PubMed ID: 24793877
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, cytotoxicity and topoisomerase II inhibitory activity of lomefloxacin derivatives.
Zhou Y; Xu X; Sun Y; Wang H; Sun H; You Q
Bioorg Med Chem Lett; 2013 May; 23(10):2974-8. PubMed ID: 23566520
[TBL] [Abstract][Full Text] [Related]
15. An efficient one-pot synthesis of benzothiazolo-4β-anilino-podophyllotoxin congeners: DNA topoisomerase-II inhibition and anticancer activity.
Kamal A; Kumar BA; Suresh P; Shankaraiah N; Kumar MS
Bioorg Med Chem Lett; 2011 Jan; 21(1):350-3. PubMed ID: 21144748
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis, cytotoxicity, HuTopoIIα inhibitory activity and molecular docking studies of pyrazole derivatives as potential anticancer agents.
Alam R; Wahi D; Singh R; Sinha D; Tandon V; Grover A; Rahisuddin
Bioorg Chem; 2016 Dec; 69():77-90. PubMed ID: 27744115
[TBL] [Abstract][Full Text] [Related]
17. Search for human DNA topoisomerase II poisons in the group of 2,5-disubstituted-1,3,4-thiadiazoles.
Plech T; Kaproń B; Paneth A; Wujec M; Czarnomysy R; Bielawska A; Bielawski K; Trotsko N; Kuśmierz E; Paneth P
J Enzyme Inhib Med Chem; 2015 Dec; 30(6):1021-6. PubMed ID: 25792499
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and evaluation of novel podophyllotoxin analogs.
Li J; Hua HM; Tang YB; Zhang S; Ohkoshi E; Lee KH; Xiao Zy
Bioorg Med Chem Lett; 2012 Jul; 22(13):4293-5. PubMed ID: 22658864
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and evaluation of aroylthiourea derivatives of 4-β-amino-4'-O-demethyl-4-desoxypodophyllotoxin as novel topoisomerase II inhibitors.
Zhao Y; Ge CW; Wu ZH; Wang CN; Fang JH; Zhu L
Eur J Med Chem; 2011 Mar; 46(3):901-6. PubMed ID: 21277655
[TBL] [Abstract][Full Text] [Related]
20. Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors.
Eissa IH; Metwaly AM; Belal A; Mehany ABM; Ayyad RR; El-Adl K; Mahdy HA; Taghour MS; El-Gamal KMA; El-Sawah ME; Elmetwally SA; Elhendawy MA; Radwan MM; ElSohly MA
Arch Pharm (Weinheim); 2019 Nov; 352(11):e1900123. PubMed ID: 31463953
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]