These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 29290767)

  • 1. Efficacy of Shikonin against Esophageal Cancer Cells and its possible mechanisms
    Tang JC; Zhao J; Long F; Chen JY; Mu B; Jiang Z; Ren Y; Yang J
    J Cancer; 2018; 9(1):32-40. PubMed ID: 29290767
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metformin inhibits gastric cancer via the inhibition of HIF1α/PKM2 signaling.
    Chen G; Feng W; Zhang S; Bian K; Yang Y; Fang C; Chen M; Yang J; Zou X
    Am J Cancer Res; 2015; 5(4):1423-34. PubMed ID: 26101707
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Shikonin induces hepatocellular carcinoma cell apoptosis by suppressing PKM2/PHD3/HIF-1
    Zhang H; Chen Z; Zhao X; Huo Q; Cheng X
    Nan Fang Yi Ke Da Xue Xue Bao; 2023 Jan; 43(1):92-98. PubMed ID: 36856215
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Shikonin enhances sensitization of gefitinib against wild-type EGFR non-small cell lung cancer via inhibition PKM2/stat3/cyclinD1 signal pathway.
    Tang JC; Ren YG; Zhao J; Long F; Chen JY; Jiang Z
    Life Sci; 2018 Jul; 204():71-77. PubMed ID: 29738778
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Experimental Study of Hepatocellular Carcinoma Treatment by Shikonin Through Regulating PKM2.
    Liu T; Li S; Wu L; Yu Q; Li J; Feng J; Zhang J; Chen J; Zhou Y; Ji J; Chen K; Mao Y; Wang F; Dai W; Fan X; Wu J; Guo C
    J Hepatocell Carcinoma; 2020; 7():19-31. PubMed ID: 32110554
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Shikonin Inhibits Tumor Growth of ESCC by suppressing PKM2 mediated Aerobic Glycolysis and STAT3 Phosphorylation.
    Zhang Q; Liu Q; Zheng S; Liu T; Yang L; Han X; Lu X
    J Cancer; 2021; 12(16):4830-4840. PubMed ID: 34234853
    [No Abstract]   [Full Text] [Related]  

  • 7. Effects and Mechanisms of Metformin on the Proliferation of Esophageal Cancer Cells
    Tang JC; An R; Jiang YQ; Yang J
    Cancer Res Treat; 2017 Jul; 49(3):778-789. PubMed ID: 27857021
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line.
    Yang W; Liu J; Hou L; Chen Q; Liu Y
    Life Sci; 2021 Jan; 265():118796. PubMed ID: 33220292
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of Pyruvate kinase M2 (PKM2) by shikonin attenuates isoproterenol-induced acute myocardial infarction via reduction in inflammation, hypoxia, apoptosis, and fibrosis.
    Rihan M; Sharma SS
    Naunyn Schmiedebergs Arch Pharmacol; 2024 Jan; 397(1):145-159. PubMed ID: 37382601
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Shikonin inhibits growth, invasion and glycolysis of nasopharyngeal carcinoma cells through inactivating the phosphatidylinositol 3 kinase/AKT signal pathway.
    Zhang J; Zhou J; Xiao S
    Anticancer Drugs; 2020 Oct; 31(9):932-941. PubMed ID: 32282369
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Combination Treatment Using Pyruvate Kinase M2 Inhibitors for the Sensitization of High Density Triple-negative Breast Cancer Cells.
    Lee JS; Oh Y; Lee JS; Park JH; Shin JK; Han JH; Kim HS; Yoon S
    In Vivo; 2022; 36(5):2105-2115. PubMed ID: 36099094
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Shikonin inhibited glycolysis and sensitized cisplatin treatment in non-small cell lung cancer cells via the exosomal pyruvate kinase M2 pathway.
    Dai Y; Liu Y; Li J; Jin M; Yang H; Huang G
    Bioengineered; 2022 May; 13(5):13906-13918. PubMed ID: 35706397
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PKM2 Is Overexpressed in Glioma Tissues, and Its Inhibition Highly Increases Late Apoptosis in U87MG Cells With Low-density Specificity.
    Park JH; Lee JS; Oh Y; Lee JS; Park HE; Lee H; Park YS; Kyung SY; Kim HS; Yoon S
    In Vivo; 2022; 36(2):694-703. PubMed ID: 35241524
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antitumor Effect of Shikonin, a PKM2 Inhibitor, in Cholangiocarcinoma Cell Lines.
    Thonsri U; Seubwai W; Waraasawapati S; Wongkham S; Boonmars T; Cha'on U; Wongkham C
    Anticancer Res; 2020 Sep; 40(9):5115-5124. PubMed ID: 32878800
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Shikonin Inhibits Tumor Growth in Mice by Suppressing Pyruvate Kinase M2-mediated Aerobic Glycolysis.
    Zhao X; Zhu Y; Hu J; Jiang L; Li L; Jia S; Zen K
    Sci Rep; 2018 Sep; 8(1):14517. PubMed ID: 30266938
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PKM2 inhibitor shikonin suppresses TPA-induced mitochondrial malfunction and proliferation of skin epidermal JB6 cells.
    Li W; Liu J; Zhao Y
    Mol Carcinog; 2014 May; 53(5):403-12. PubMed ID: 23255458
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Shikonin Suppresses Skin Carcinogenesis via Inhibiting Cell Proliferation.
    Li W; Zhang C; Ren A; Li T; Jin R; Li G; Gu X; Shi R; Zhao Y
    PLoS One; 2015; 10(5):e0126459. PubMed ID: 25961580
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HIF-1α regulates the cell viability in radioiodine-resistant papillary thyroid carcinoma cells induced by hypoxia through PKM2/NF-κB signaling pathway.
    Wang D; Liu X; Li M; Ning J
    Mol Carcinog; 2024 Feb; 63(2):238-252. PubMed ID: 37861358
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth.
    Sun Q; Chen X; Ma J; Peng H; Wang F; Zha X; Wang Y; Jing Y; Yang H; Chen R; Chang L; Zhang Y; Goto J; Onda H; Chen T; Wang MR; Lu Y; You H; Kwiatkowski D; Zhang H
    Proc Natl Acad Sci U S A; 2011 Mar; 108(10):4129-34. PubMed ID: 21325052
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Shikonin suppresses proliferation and induces cell cycle arrest through the inhibition of hypoxia-inducible factor-1α signaling.
    Li MY; Mi C; Wang KS; Wang Z; Zuo HX; Piao LX; Xu GH; Li X; Ma J; Jin X
    Chem Biol Interact; 2017 Aug; 274():58-67. PubMed ID: 28684144
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.