BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

308 related articles for article (PubMed ID: 29295922)

  • 1. CDC42 binds PAK4 via an extended GTPase-effector interface.
    Ha BH; Boggon TJ
    Proc Natl Acad Sci U S A; 2018 Jan; 115(3):531-536. PubMed ID: 29295922
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The subcellular localization of type I p21-activated kinases is controlled by the disordered variable region and polybasic sequences.
    Sun X; Su VL; Calderwood DA
    J Biol Chem; 2019 Sep; 294(39):14319-14332. PubMed ID: 31391252
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of Cdc42 bound to the GTPase binding domain of PAK.
    Morreale A; Venkatesan M; Mott HR; Owen D; Nietlispach D; Lowe PN; Laue ED
    Nat Struct Biol; 2000 May; 7(5):384-8. PubMed ID: 10802735
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Mutations in the Effector Domain of RhoV GTPase Impair Its Binding to Pak1 Protein Kinase].
    Korobko IV; Shepelev MV
    Mol Biol (Mosk); 2018; 52(4):692-698. PubMed ID: 30113035
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oncogenic Dbl, Cdc42, and p21-activated kinase form a ternary signaling intermediate through the minimum interactive domains.
    Wang L; Zhu K; Zheng Y
    Biochemistry; 2004 Nov; 43(46):14584-93. PubMed ID: 15544329
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A bivalent dissectional analysis of the high-affinity interactions between Cdc42 and the Cdc42/Rac interactive binding domains of signaling kinases in Candida albicans.
    Su Z; Osborne MJ; Xu P; Xu X; Li Y; Ni F
    Biochemistry; 2005 Dec; 44(50):16461-74. PubMed ID: 16342938
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A dock and coalesce mechanism driven by hydrophobic interactions governs Cdc42 binding with its effector protein ACK.
    Tetley GJN; Mott HR; Cooley RN; Owen D
    J Biol Chem; 2017 Jul; 292(27):11361-11373. PubMed ID: 28539360
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Group I and II mammalian PAKs have different modes of activation by Cdc42.
    Baskaran Y; Ng YW; Selamat W; Ling FT; Manser E
    EMBO Rep; 2012 Jun; 13(7):653-9. PubMed ID: 22653441
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia.
    Abo A; Qu J; Cammarano MS; Dan C; Fritsch A; Baud V; Belisle B; Minden A
    EMBO J; 1998 Nov; 17(22):6527-40. PubMed ID: 9822598
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cdc42- and Rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling.
    Koh W; Mahan RD; Davis GE
    J Cell Sci; 2008 Apr; 121(Pt 7):989-1001. PubMed ID: 18319301
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain.
    Pandey A; Dan I; Kristiansen TZ; Watanabe NM; Voldby J; Kajikawa E; Khosravi-Far R; Blagoev B; Mann M
    Oncogene; 2002 May; 21(24):3939-48. PubMed ID: 12032833
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity.
    Selamat W; Tay PL; Baskaran Y; Manser E
    PLoS One; 2015; 10(6):e0129634. PubMed ID: 26068882
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PAK6 targets to cell-cell adhesions through its N-terminus in a Cdc42-dependent manner to drive epithelial colony escape.
    Morse EM; Sun X; Olberding JR; Ha BH; Boggon TJ; Calderwood DA
    J Cell Sci; 2016 Jan; 129(2):380-93. PubMed ID: 26598554
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional cross-talk between Cdc42 and two downstream targets, Par6B and PAK4.
    Jin D; Durgan J; Hall A
    Biochem J; 2015 Apr; 467(2):293-302. PubMed ID: 25662318
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein.
    Abdul-Manan N; Aghazadeh B; Liu GA; Majumdar A; Ouerfelli O; Siminovitch KA; Rosen MK
    Nature; 1999 May; 399(6734):379-83. PubMed ID: 10360578
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cdc42 regulates apical junction formation in human bronchial epithelial cells through PAK4 and Par6B.
    Wallace SW; Durgan J; Jin D; Hall A
    Mol Biol Cell; 2010 Sep; 21(17):2996-3006. PubMed ID: 20631255
    [TBL] [Abstract][Full Text] [Related]  

  • 17. N-terminal interaction domain implicates PAK4 in translational regulation and reveals novel cellular localization signals.
    Baldassa S; Calogero AM; Colombo G; Zippel R; Gnesutta N
    J Cell Physiol; 2010 Sep; 224(3):722-33. PubMed ID: 20578242
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Residues in Cdc42 that specify binding to individual CRIB effector proteins.
    Owen D; Mott HR; Laue ED; Lowe PN
    Biochemistry; 2000 Feb; 39(6):1243-50. PubMed ID: 10684602
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors.
    Kast DJ; Yang C; Disanza A; Boczkowska M; Madasu Y; Scita G; Svitkina T; Dominguez R
    Nat Struct Mol Biol; 2014 Apr; 21(4):413-22. PubMed ID: 24584464
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Intrinsic GTP hydrolysis is observed for a switch 1 variant of Cdc42 in the presence of a specific GTPase inhibitor.
    Morris KM; Henderson R; Suresh Kumar TK; Heyes CD; Adams PD
    Small GTPases; 2016; 7(1):1-11. PubMed ID: 26828437
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.