880 related articles for article (PubMed ID: 29298813)
1. G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?
Sriram K; Insel PA
Mol Pharmacol; 2018 Apr; 93(4):251-258. PubMed ID: 29298813
[TBL] [Abstract][Full Text] [Related]
2. Established and In-trial GPCR Families in Clinical Trials: A Review for Target Selection.
Saikia S; Bordoloi M; Sarmah R
Curr Drug Targets; 2019; 20(5):522-539. PubMed ID: 30394207
[TBL] [Abstract][Full Text] [Related]
3. G Protein-Coupled Receptor (GPCR) Expression in Native Cells: "Novel" endoGPCRs as Physiologic Regulators and Therapeutic Targets.
Insel PA; Wilderman A; Zambon AC; Snead AN; Murray F; Aroonsakool N; McDonald DS; Zhou S; McCann T; Zhang L; Sriram K; Chinn AM; Michkov AV; Lynch RM; Overland AC; Corriden R
Mol Pharmacol; 2015 Jul; 88(1):181-7. PubMed ID: 25737495
[TBL] [Abstract][Full Text] [Related]
4. Emerging concepts of guanine nucleotide-binding protein-coupled receptor (GPCR) function and implications for high throughput screening.
Eglen RM; Bosse R; Reisine T
Assay Drug Dev Technol; 2007 Jun; 5(3):425-51. PubMed ID: 17638542
[TBL] [Abstract][Full Text] [Related]
5. Orphan G protein-coupled receptors (GPCRs): biological functions and potential drug targets.
Tang XL; Wang Y; Li DL; Luo J; Liu MY
Acta Pharmacol Sin; 2012 Mar; 33(3):363-71. PubMed ID: 22367282
[TBL] [Abstract][Full Text] [Related]
6. Quantitative and systems pharmacology 2. In silico polypharmacology of G protein-coupled receptor ligands via network-based approaches.
Wu Z; Lu W; Yu W; Wang T; Li W; Liu G; Zhang H; Pang X; Huang J; Liu M; Cheng F; Tang Y
Pharmacol Res; 2018 Mar; 129():400-413. PubMed ID: 29133212
[TBL] [Abstract][Full Text] [Related]
7. Unintended Effects of GPCR-Targeted Drugs on the Cancer Phenotype.
Cornwell AC; Feigin ME
Trends Pharmacol Sci; 2020 Dec; 41(12):1006-1022. PubMed ID: 33198923
[TBL] [Abstract][Full Text] [Related]
8. Experimental challenges to targeting poorly characterized GPCRs: uncovering the therapeutic potential for free fatty acid receptors.
Hudson BD; Smith NJ; Milligan G
Adv Pharmacol; 2011; 62():175-218. PubMed ID: 21907910
[TBL] [Abstract][Full Text] [Related]
9. Comparing Class A GPCRs to bitter taste receptors: Structural motifs, ligand interactions and agonist-to-antagonist ratios.
Di Pizio A; Levit A; Slutzki M; Behrens M; Karaman R; Niv MY
Methods Cell Biol; 2016; 132():401-27. PubMed ID: 26928553
[TBL] [Abstract][Full Text] [Related]
10. Genetic variation in G-protein-coupled receptors--consequences for G-protein-coupled receptors as drug targets.
Tang CM; Insel PA
Expert Opin Ther Targets; 2005 Dec; 9(6):1247-65. PubMed ID: 16300474
[TBL] [Abstract][Full Text] [Related]
11. Cell-based assays in GPCR drug discovery.
Siehler S
Biotechnol J; 2008 Apr; 3(4):471-83. PubMed ID: 18383022
[TBL] [Abstract][Full Text] [Related]
12. Beyond the Ligand: Extracellular and Transcellular G Protein-Coupled Receptor Complexes in Physiology and Pharmacology.
Dunn HA; Orlandi C; Martemyanov KA
Pharmacol Rev; 2019 Oct; 71(4):503-519. PubMed ID: 31515243
[TBL] [Abstract][Full Text] [Related]
13. Trends in GPCR drug discovery: new agents, targets and indications.
Hauser AS; Attwood MM; Rask-Andersen M; Schiöth HB; Gloriam DE
Nat Rev Drug Discov; 2017 Dec; 16(12):829-842. PubMed ID: 29075003
[TBL] [Abstract][Full Text] [Related]
14. GLIDA: GPCR-ligand database for chemical genomic drug discovery.
Okuno Y; Yang J; Taneishi K; Yabuuchi H; Tsujimoto G
Nucleic Acids Res; 2006 Jan; 34(Database issue):D673-7. PubMed ID: 16381956
[TBL] [Abstract][Full Text] [Related]
15. GPCRomics: An Approach to Discover GPCR Drug Targets.
Insel PA; Sriram K; Gorr MW; Wiley SZ; Michkov A; Salmerón C; Chinn AM
Trends Pharmacol Sci; 2019 Jun; 40(6):378-387. PubMed ID: 31078319
[TBL] [Abstract][Full Text] [Related]
16. Strategies to discover unexpected targets for drugs active at G protein-coupled receptors.
Allen JA; Roth BL
Annu Rev Pharmacol Toxicol; 2011; 51():117-44. PubMed ID: 20868273
[TBL] [Abstract][Full Text] [Related]
17. Identification of Dysregulated Expression of G Protein Coupled Receptors in Endocrine Tumors by Bioinformatics Analysis: Potential Drug Targets?
Suteau V; Munier M; Ben Boubaker R; Wery M; Henrion D; Rodien P; Briet C
Cells; 2022 Feb; 11(4):. PubMed ID: 35203352
[TBL] [Abstract][Full Text] [Related]
18. GPCR systems pharmacology: a different perspective on the development of biased therapeutics.
Eiger DS; Pham U; Gardner J; Hicks C; Rajagopal S
Am J Physiol Cell Physiol; 2022 May; 322(5):C887-C895. PubMed ID: 35196164
[TBL] [Abstract][Full Text] [Related]
19. Non-invasive optical biosensor for assaying endogenous G protein-coupled receptors in adherent cells.
Fang Y; Li G; Ferrie AM
J Pharmacol Toxicol Methods; 2007; 55(3):314-22. PubMed ID: 17207642
[TBL] [Abstract][Full Text] [Related]
20. Targeting platelet G-protein coupled receptors (GPCRs): looking beyond conventional GPCR antagonism.
Dowal L; Flaumenhaft R
Curr Vasc Pharmacol; 2010 Mar; 8(2):140-54. PubMed ID: 19485898
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
