233 related articles for article (PubMed ID: 29305421)
1. Fluid flow modulates electrical activity in cardiac hERG potassium channels.
Roy S; Mathew MK
J Biol Chem; 2018 Mar; 293(12):4289-4303. PubMed ID: 29305421
[TBL] [Abstract][Full Text] [Related]
2. Electrophysiological characterization of the modified hERG
Zhang Y; Dempsey CE; Hancox JC
Physiol Rep; 2020 Oct; 8(20):e14568. PubMed ID: 33091232
[TBL] [Abstract][Full Text] [Related]
3. Rescue of aberrant gating by a genetically encoded PAS (Per-Arnt-Sim) domain in several long QT syndrome mutant human ether-á-go-go-related gene potassium channels.
Gianulis EC; Trudeau MC
J Biol Chem; 2011 Jun; 286(25):22160-9. PubMed ID: 21536673
[TBL] [Abstract][Full Text] [Related]
4. hERG1a and hERG1b potassium channel subunits directly interact and preferentially form heteromeric channels.
McNally BA; Pendon ZD; Trudeau MC
J Biol Chem; 2017 Dec; 292(52):21548-21557. PubMed ID: 29089383
[TBL] [Abstract][Full Text] [Related]
5. Fentanyl-Induced Block of hERG Channels Is Exacerbated by Hypoxia, Hypokalemia, Alkalosis, and the Presence of hERG1b.
Tschirhart JN; Zhang S
Mol Pharmacol; 2020 Oct; 98(4):508-517. PubMed ID: 32321735
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of the HERG channel by droperidol depends on channel gating and involves the S6 residue F656.
Luo T; Luo A; Liu M; Liu X
Anesth Analg; 2008 Apr; 106(4):1161-70, table of contents. PubMed ID: 18349188
[TBL] [Abstract][Full Text] [Related]
7. Discovery of a small molecule activator of the human ether-a-go-go-related gene (HERG) cardiac K+ channel.
Kang J; Chen XL; Wang H; Ji J; Cheng H; Incardona J; Reynolds W; Viviani F; Tabart M; Rampe D
Mol Pharmacol; 2005 Mar; 67(3):827-36. PubMed ID: 15548764
[TBL] [Abstract][Full Text] [Related]
8. Determinants of Isoform-Specific Gating Kinetics of hERG1 Channel: Combined Experimental and Simulation Study.
Perissinotti LL; De Biase PM; Guo J; Yang PC; Lee MC; Clancy CE; Duff HJ; Noskov SY
Front Physiol; 2018; 9():207. PubMed ID: 29706893
[TBL] [Abstract][Full Text] [Related]
9. Voltage-dependent activation in EAG channels follows a ligand-receptor rather than a mechanical-lever mechanism.
Malak OA; Gluhov GS; Grizel AV; Kudryashova KS; Sokolova OS; Loussouarn G
J Biol Chem; 2019 Apr; 294(16):6506-6521. PubMed ID: 30808709
[TBL] [Abstract][Full Text] [Related]
10. The hERG channel activator, RPR260243, enhances protective
Shi YP; Pang Z; Venkateshappa R; Gunawan M; Kemp J; Truong E; Chang C; Lin E; Shafaattalab S; Faizi S; Rayani K; Tibbits GF; Claydon VE; Claydon TW
Am J Physiol Heart Circ Physiol; 2020 Aug; 319(2):H251-H261. PubMed ID: 32559136
[TBL] [Abstract][Full Text] [Related]
11. hERG1a N-terminal eag domain-containing polypeptides regulate homomeric hERG1b and heteromeric hERG1a/hERG1b channels: a possible mechanism for long QT syndrome.
Trudeau MC; Leung LM; Roti ER; Robertson GA
J Gen Physiol; 2011 Dec; 138(6):581-92. PubMed ID: 22124116
[TBL] [Abstract][Full Text] [Related]
12. Voltage-shift of the current activation in HERG S4 mutation (R534C) in LQT2.
Nakajima T; Furukawa T; Hirano Y; Tanaka T; Sakurada H; Takahashi T; Nagai R; Itoh T; Katayama Y; Nakamura Y; Hiraoka M
Cardiovasc Res; 1999 Nov; 44(2):283-93. PubMed ID: 10690305
[TBL] [Abstract][Full Text] [Related]
13. Serine mutation of a conserved threonine in the hERG K
Al-Moubarak E; Zhang Y; Dempsey CE; Zhang H; Harmer SC; Hancox JC
Biochem Biophys Res Commun; 2020 Jun; 526(4):1085-1091. PubMed ID: 32321643
[TBL] [Abstract][Full Text] [Related]
14. Conformation-sensitive antibody reveals an altered cytosolic PAS/CNBh assembly during hERG channel gating.
Harley CA; Bernardo-Seisdedos G; Stevens-Sostre WA; Jones DK; Azevedo MM; Sampaio P; Lorga-Gomes M; Trudeau MC; Millet O; Robertson GA; Morais-Cabral JH
Proc Natl Acad Sci U S A; 2021 Nov; 118(44):. PubMed ID: 34716268
[TBL] [Abstract][Full Text] [Related]
15. Targeted activation of human ether-à-go-go-related gene channels rescues electrical instability induced by the R56Q+/- long QT syndrome variant.
Venkateshappa R; Hunter DV; Muralidharan P; Nagalingam RS; Huen G; Faizi S; Luthra S; Lin E; Cheng YM; Hughes J; Khelifi R; Dhunna DP; Johal R; Sergeev V; Shafaattalab S; Julian LM; Poburko DT; Laksman Z; Tibbits GF; Claydon TW
Cardiovasc Res; 2023 Nov; 119(15):2522-2535. PubMed ID: 37739930
[TBL] [Abstract][Full Text] [Related]
16. Enhancement of hERG channel activity by scFv antibody fragments targeted to the PAS domain.
Harley CA; Starek G; Jones DK; Fernandes AS; Robertson GA; Morais-Cabral JH
Proc Natl Acad Sci U S A; 2016 Aug; 113(35):9916-21. PubMed ID: 27516548
[TBL] [Abstract][Full Text] [Related]
17. The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT.
Mechakra A; Vincent Y; Chevalier P; Millat G; Ficker E; Jastrzebski M; Poulin H; Pouliot V; Chahine M; Christé G
Gene; 2014 Feb; 536(2):348-56. PubMed ID: 24334129
[TBL] [Abstract][Full Text] [Related]
18. Altered gating of HERG potassium channels by cobalt and lanthanum.
Sanchez-Chapula JA; Sanguinetti MC
Pflugers Arch; 2000 Jun; 440(2):264-74. PubMed ID: 10898527
[TBL] [Abstract][Full Text] [Related]
19. The influence of hERG1a and hERG1b isoforms on drug safety screening in iPSC-CMs.
Goversen B; Jonsson MK; van den Heuvel NH; Rijken R; Vos MA; van Veen TA; de Boer TP
Prog Biophys Mol Biol; 2019 Dec; 149():86-98. PubMed ID: 30826123
[TBL] [Abstract][Full Text] [Related]
20. hERG1 channel subunit composition mediates proton inhibition of rapid delayed rectifier potassium current (I
Ukachukwu CU; Jimenez-Vazquez EN; Jain A; Jones DK
J Biol Chem; 2023 Feb; 299(2):102778. PubMed ID: 36496073
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
