139 related articles for article (PubMed ID: 29305921)
1. Distribution of therapeutic proteins into thoracic lymph after intravenous administration is protein size-dependent and primarily occurs within the liver and mesentery.
Yadav P; McLeod VM; Nowell CJ; Selby LI; Johnston APR; Kaminskas LM; Trevaskis NL
J Control Release; 2018 Feb; 272():17-28. PubMed ID: 29305921
[TBL] [Abstract][Full Text] [Related]
2. PEGylation of interferon α2 improves lymphatic exposure after subcutaneous and intravenous administration and improves antitumour efficacy against lymphatic breast cancer metastases.
Kaminskas LM; Ascher DB; McLeod VM; Herold MJ; Le CP; Sloan EK; Porter CJ
J Control Release; 2013 Jun; 168(2):200-8. PubMed ID: 23499718
[TBL] [Abstract][Full Text] [Related]
3. PEGylation does not significantly change the initial intravenous or subcutaneous pharmacokinetics or lymphatic exposure of trastuzumab in rats but increases plasma clearance after subcutaneous administration.
Chan LJ; Bulitta JB; Ascher DB; Haynes JM; McLeod VM; Porter CJ; Williams CC; Kaminskas LM
Mol Pharm; 2015 Mar; 12(3):794-809. PubMed ID: 25644368
[TBL] [Abstract][Full Text] [Related]
4. PEGylated polylysine dendrimers increase lymphatic exposure to doxorubicin when compared to PEGylated liposomal and solution formulations of doxorubicin.
Ryan GM; Kaminskas LM; Bulitta JB; McIntosh MP; Owen DJ; Porter CJH
J Control Release; 2013 Nov; 172(1):128-136. PubMed ID: 23954628
[TBL] [Abstract][Full Text] [Related]
5. Removal of interstitial hyaluronan with recombinant human hyaluronidase improves the systemic and lymphatic uptake of cetuximab in rats.
Styles IK; Feeney OM; Nguyen TH; Brundel DHS; Kang DW; Clift R; McIntosh MP; Porter CJH
J Control Release; 2019 Dec; 315():85-96. PubMed ID: 31655131
[TBL] [Abstract][Full Text] [Related]
6. PEGylation of polylysine dendrimers improves absorption and lymphatic targeting following SC administration in rats.
Kaminskas LM; Kota J; McLeod VM; Kelly BD; Karellas P; Porter CJ
J Control Release; 2009 Dec; 140(2):108-16. PubMed ID: 19686787
[TBL] [Abstract][Full Text] [Related]
7. Organ-specific lymphatics play distinct roles in regulating HDL trafficking and composition.
Gracia G; Cao E; Johnston APR; Porter CJH; Trevaskis NL
Am J Physiol Gastrointest Liver Physiol; 2020 Apr; 318(4):G725-G735. PubMed ID: 32068443
[TBL] [Abstract][Full Text] [Related]
8. The lymphatic system plays a major role in the intravenous and subcutaneous pharmacokinetics of trastuzumab in rats.
Dahlberg AM; Kaminskas LM; Smith A; Nicolazzo JA; Porter CJ; Bulitta JB; McIntosh MP
Mol Pharm; 2014 Feb; 11(2):496-504. PubMed ID: 24350780
[TBL] [Abstract][Full Text] [Related]
9. Impact of conjugation to different lipids on the lymphatic uptake and biodistribution of brush PEG polymers.
Abdallah M; Lin L; Styles IK; Mörsdorf A; Grace JL; Gracia G; Landersdorfer CB; Nowell CJ; Quinn JF; Whittaker MR; Trevaskis NL
J Control Release; 2024 May; 369():146-162. PubMed ID: 38513730
[TBL] [Abstract][Full Text] [Related]
10. Evaluation of the absolute bioavailability of pegylated interferon alfa-2a after subcutaneous administration to healthy male volunteers: an open-label, randomized, parallel-group study.
Brennan BJ; Xu ZX; Grippo JF
Clin Ther; 2012 Sep; 34(9):1883-91. PubMed ID: 22858176
[TBL] [Abstract][Full Text] [Related]
11. Improved pharmacokinetic properties of a polyethylene glycol-modified form of interferon-beta-1a with preserved in vitro bioactivity.
Pepinsky RB; LePage DJ; Gill A; Chakraborty A; Vaidyanathan S; Green M; Baker DP; Whalley E; Hochman PS; Martin P
J Pharmacol Exp Ther; 2001 Jun; 297(3):1059-66. PubMed ID: 11356929
[TBL] [Abstract][Full Text] [Related]
12. A Comparison of the Pharmacokinetics and Pulmonary Lymphatic Exposure of a Generation 4 PEGylated Dendrimer Following Intravenous and Aerosol Administration to Rats and Sheep.
Ryan GM; Bischof RJ; Enkhbaatar P; McLeod VM; Chan LJ; Jones SA; Owen DJ; Porter CJ; Kaminskas LM
Pharm Res; 2016 Feb; 33(2):510-25. PubMed ID: 26486513
[TBL] [Abstract][Full Text] [Related]
13. Conjugation of 10 kDa Linear PEG onto Trastuzumab Fab' Is Sufficient to Significantly Enhance Lymphatic Exposure while Preserving in Vitro Biological Activity.
Chan LJ; Ascher DB; Yadav R; Bulitta JB; Williams CC; Porter CJ; Landersdorfer CB; Kaminskas LM
Mol Pharm; 2016 Apr; 13(4):1229-41. PubMed ID: 26871003
[TBL] [Abstract][Full Text] [Related]
14. Optimal PEGylation can improve the exposure of interferon in the lungs following pulmonary administration.
Mcleod VM; Chan LJ; Ryan GM; Porter CJ; Kaminskas LM
J Pharm Sci; 2015 Apr; 104(4):1421-30. PubMed ID: 25631360
[TBL] [Abstract][Full Text] [Related]
15. Intra-articular injection of biologic anti-rheumatic drugs enhances local exposure to the joint-draining lymphatics.
Lam AD; Cao E; Leong N; Gracia G; Porter CJH; Feeney OM; Trevaskis NL
Eur J Pharm Biopharm; 2022 Apr; 173():34-44. PubMed ID: 35219864
[TBL] [Abstract][Full Text] [Related]
16. Comparative Pharmacokinetics, Tissue Distribution, Excretion of Recombinant Liver-Targeting Interferon with IFN α2b Administered Intramuscular in Rats.
Wang J; Lu X; Jin X; Zeng W; Zhu J
Curr Pharm Biotechnol; 2015; 16(10):911-9. PubMed ID: 26278706
[TBL] [Abstract][Full Text] [Related]
17. Lymphatic transport and catabolism of therapeutic proteins after subcutaneous administration to rats and dogs.
Wang W; Chen N; Shen X; Cunningham P; Fauty S; Michel K; Wang B; Hong X; Adreani C; Nunes CN; Johnson CV; Yin KC; Groff M; Zou Y; Liu L; Hamuro L; Prueksaritanont T
Drug Metab Dispos; 2012 May; 40(5):952-62. PubMed ID: 22328584
[TBL] [Abstract][Full Text] [Related]
18. Lymphatic Uptake of Liposomes after Intraperitoneal Administration Primarily Occurs via the Diaphragmatic Lymphatics and is Dependent on Liposome Surface Properties.
Lee G; Han S; Inocencio I; Cao E; Hong J; Phillips ARJ; Windsor JA; Porter CJH; Trevaskis NL
Mol Pharm; 2019 Dec; 16(12):4987-4999. PubMed ID: 31625752
[TBL] [Abstract][Full Text] [Related]
19. A frustrating problem: accelerated blood clearance of PEGylated solid lipid nanoparticles following subcutaneous injection in rats.
Zhao Y; Wang C; Wang L; Yang Q; Tang W; She Z; Deng Y
Eur J Pharm Biopharm; 2012 Aug; 81(3):506-13. PubMed ID: 22580209
[TBL] [Abstract][Full Text] [Related]
20. Nanoparticles with dense poly(ethylene glycol) coatings with near neutral charge are maximally transported across lymphatics and to the lymph nodes.
McCright J; Skeen C; Yarmovsky J; Maisel K
Acta Biomater; 2022 Jun; 145():146-158. PubMed ID: 35381399
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
