850 related articles for article (PubMed ID: 29306206)
1. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
Zhou P; Liang Y; Zhang H; Jiang H; Feng K; Xu P; Wang J; Wang X; Ding K; Luo C; Liu M; Wang Y
Eur J Med Chem; 2018 Jan; 144():817-842. PubMed ID: 29306206
[TBL] [Abstract][Full Text] [Related]
2. Potent Antitumor Activities and Structure Basis of the Chiral β-Lactam Bridged Analogue of Combretastatin A-4 Binding to Tubulin.
Zhou P; Liu Y; Zhou L; Zhu K; Feng K; Zhang H; Liang Y; Jiang H; Luo C; Liu M; Wang Y
J Med Chem; 2016 Nov; 59(22):10329-10334. PubMed ID: 27805821
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
Stefański T; Mikstacka R; Kurczab R; Dutkiewicz Z; Kucińska M; Murias M; Zielińska-Przyjemska M; Cichocki M; Teubert A; Kaczmarek M; Hogendorf A; Sobiak S
Eur J Med Chem; 2018 Jan; 144():797-816. PubMed ID: 29291446
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
Wang G; Li C; He L; Lei K; Wang F; Pu Y; Yang Z; Cao D; Ma L; Chen J; Sang Y; Liang X; Xiang M; Peng A; Wei Y; Chen L
Bioorg Med Chem; 2014 Apr; 22(7):2060-79. PubMed ID: 24629450
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, and biological evaluation of hydantoin bridged analogues of combretastatin A-4 as potential anticancer agents.
Zhang M; Liang YR; Li H; Liu MM; Wang Y
Bioorg Med Chem; 2017 Dec; 25(24):6623-6634. PubMed ID: 29126741
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and Biological Evaluations of 1,2-Diaryl Pyrroles as Analogues of Combretastatin A-4.
Sun J; Chen L; Liu C; Wang Z; Zuo D; Pan J; Qi H; Bao K; Wu Y; Zhang W
Chem Biol Drug Des; 2015 Dec; 86(6):1541-7. PubMed ID: 26202587
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents.
O'Boyle NM; Carr M; Greene LM; Bergin O; Nathwani SM; McCabe T; Lloyd DG; Zisterer DM; Meegan MJ
J Med Chem; 2010 Dec; 53(24):8569-84. PubMed ID: 21080725
[TBL] [Abstract][Full Text] [Related]
8. Lead identification of conformationally restricted β-lactam type combretastatin analogues: synthesis, antiproliferative activity and tubulin targeting effects.
Carr M; Greene LM; Knox AJ; Lloyd DG; Zisterer DM; Meegan MJ
Eur J Med Chem; 2010 Dec; 45(12):5752-66. PubMed ID: 20933304
[TBL] [Abstract][Full Text] [Related]
9. Synthesis of Combretastatin-A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization.
Jadala C; Sathish M; Anchi P; Tokala R; Lakshmi UJ; Reddy VG; Shankaraiah N; Godugu C; Kamal A
ChemMedChem; 2019 Dec; 14(24):2052-2060. PubMed ID: 31674147
[TBL] [Abstract][Full Text] [Related]
10. Design, Synthesis and Antitumor Activity of Novel link-bridge and B-Ring Modified Combretastatin A-4 (CA-4) Analogues as Potent Antitubulin Agents.
Duan YT; Man RJ; Tang DJ; Yao YF; Tao XX; Yu C; Liang XY; Makawana JA; Zou MJ; Wang ZC; Zhu HL
Sci Rep; 2016 May; 6():25387. PubMed ID: 27138035
[TBL] [Abstract][Full Text] [Related]
11. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
Liu YN; Wang JJ; Ji YT; Zhao GD; Tang LQ; Zhang CM; Guo XL; Liu ZP
J Med Chem; 2016 Jun; 59(11):5341-55. PubMed ID: 27172319
[TBL] [Abstract][Full Text] [Related]
12. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
Romagnoli R; Kimatrai Salvador M; Schiaffino Ortega S; Baraldi PG; Oliva P; Baraldi S; Lopez-Cara LC; Brancale A; Ferla S; Hamel E; Balzarini J; Liekens S; Mattiuzzo E; Basso G; Viola G
Eur J Med Chem; 2018 Jan; 143():683-698. PubMed ID: 29220790
[TBL] [Abstract][Full Text] [Related]
13. Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors.
Cao D; Liu Y; Yan W; Wang C; Bai P; Wang T; Tang M; Wang X; Yang Z; Ma B; Ma L; Lei L; Wang F; Xu B; Zhou Y; Yang T; Chen L
J Med Chem; 2016 Jun; 59(12):5721-39. PubMed ID: 27213819
[TBL] [Abstract][Full Text] [Related]
14. Novel diaryl-2H-azirines: Antitumor hybrids for dual-targeting tubulin and DNA.
Lin S; Liang Y; Cheng J; Pan F; Wang Y
Eur J Med Chem; 2021 Mar; 214():113256. PubMed ID: 33581556
[TBL] [Abstract][Full Text] [Related]
15. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
Penthala NR; Zong H; Ketkar A; Madadi NR; Janganati V; Eoff RL; Guzman ML; Crooks PA
Eur J Med Chem; 2015 Mar; 92():212-20. PubMed ID: 25557492
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis and antiproliferative activity of the new conjugates of E7010 and resveratrol as tubulin polymerization inhibitors.
Kamal A; Ashraf M; Basha ST; Ali Hussaini SM; Singh S; Vishnuvardhan MV; Kiran B; Sridhar B
Org Biomol Chem; 2016 Jan; 14(4):1382-94. PubMed ID: 26676480
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis of combretastatin A-4 piperazine derivatives as potential antitumor agents by inhibiting tubulin polymerization and inducing autophagy in HCT116 cells.
Zhang H; Li M; Zhou X; Tang L; Chen G; Zhang Y
Eur J Med Chem; 2024 Jun; 272():116497. PubMed ID: 38759453
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
Lai Q; Wang Y; Wang R; Lai W; Tang L; Tao Y; Liu Y; Zhang R; Huang L; Xiang H; Zeng S; Gou L; Chen H; Yao Y; Yang J
Eur J Med Chem; 2018 Aug; 156():162-179. PubMed ID: 30006162
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors.
Liang Y; Zhang M; Zhou P; Liu M; Li J; Wang Y
Bioorg Chem; 2021 Oct; 115():105239. PubMed ID: 34399321
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and Biochemical Evaluation of 3-Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents.
Greene TF; Wang S; Greene LM; Nathwani SM; Pollock JK; Malebari AM; McCabe T; Twamley B; O'Boyle NM; Zisterer DM; Meegan MJ
J Med Chem; 2016 Jan; 59(1):90-113. PubMed ID: 26680364
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
