These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 29307609)

  • 1. Decreased glutathione levels cause overt motor neuron degeneration in hSOD1
    Killoy KM; Harlan BA; Pehar M; Helke KL; Johnson JA; Vargas MR
    Exp Neurol; 2018 Apr; 302():129-135. PubMed ID: 29307609
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1(G93A) mice model.
    Vargas MR; Johnson DA; Johnson JA
    Neurobiol Dis; 2011 Sep; 43(3):543-51. PubMed ID: 21600285
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
    Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nuclear localization of human SOD1 and mutant SOD1-specific disruption of survival motor neuron protein complex in transgenic amyotrophic lateral sclerosis mice.
    Gertz B; Wong M; Martin LJ
    J Neuropathol Exp Neurol; 2012 Feb; 71(2):162-77. PubMed ID: 22249462
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulation of mutant superoxide dismutase 1 aggregation by co-expression of wild-type enzyme.
    Prudencio M; Durazo A; Whitelegge JP; Borchelt DR
    J Neurochem; 2009 Feb; 108(4):1009-18. PubMed ID: 19077113
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of RAGE inhibition on the progression of the disease in hSOD1
    Liu L; Killoy KM; Vargas MR; Yamamoto Y; Pehar M
    Pharmacol Res Perspect; 2020 Aug; 8(4):e00636. PubMed ID: 32776498
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis.
    Vargas MR; Johnson DA; Sirkis DW; Messing A; Johnson JA
    J Neurosci; 2008 Dec; 28(50):13574-81. PubMed ID: 19074031
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Skeletal muscle-restricted expression of human SOD1 causes motor neuron degeneration in transgenic mice.
    Wong M; Martin LJ
    Hum Mol Genet; 2010 Jun; 19(11):2284-302. PubMed ID: 20223753
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitochondria-targeted catalase reverts the neurotoxicity of hSOD1G⁹³A astrocytes without extending the survival of ALS-linked mutant hSOD1 mice.
    Pehar M; Beeson G; Beeson CC; Johnson JA; Vargas MR
    PLoS One; 2014; 9(7):e103438. PubMed ID: 25054289
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Neuroprotection by urate on the mutant hSOD1-related cellular and Drosophila models of amyotrophic lateral sclerosis: Implication for GSH synthesis via activating Akt/GSK3β/Nrf2/GCLC pathways.
    Zhang C; Yang Y; Liang W; Wang T; Wang S; Wang X; Wang Y; Jiang H; Feng H
    Brain Res Bull; 2019 Mar; 146():287-301. PubMed ID: 30690059
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations.
    Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ
    Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Motor neuron disease in mice expressing the wild type-like D90A mutant superoxide dismutase-1.
    Jonsson PA; Graffmo KS; Brännström T; Nilsson P; Andersen PM; Marklund SL
    J Neuropathol Exp Neurol; 2006 Dec; 65(12):1126-36. PubMed ID: 17146286
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Overexpression of TDP-43 Protein in the Neuron and Oligodendrocyte Cells Causes the Progressive Motor Neuron Degeneration in the SOD1 G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.
    Lu Y; Tang C; Zhu L; Li J; Liang H; Zhang J; Xu R
    Int J Biol Sci; 2016; 12(9):1140-9. PubMed ID: 27570488
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Direct and indirect mechanisms for wild-type SOD1 to enhance the toxicity of mutant SOD1 in bigenic transgenic mice.
    Xu G; Ayers JI; Roberts BL; Brown H; Fromholt S; Green C; Borchelt DR
    Hum Mol Genet; 2015 Feb; 24(4):1019-35. PubMed ID: 25305079
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aberrant DNA and RNA Methylation Occur in Spinal Cord and Skeletal Muscle of Human SOD1 Mouse Models of ALS and in Human ALS: Targeting DNA Methylation Is Therapeutic.
    Martin LJ; Adams DA; Niedzwiecki MV; Wong M
    Cells; 2022 Oct; 11(21):. PubMed ID: 36359844
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Toll-Like Receptor-4 Inhibitor TAK-242 Attenuates Motor Dysfunction and Spinal Cord Pathology in an Amyotrophic Lateral Sclerosis Mouse Model.
    Fellner A; Barhum Y; Angel A; Perets N; Steiner I; Offen D; Lev N
    Int J Mol Sci; 2017 Aug; 18(8):. PubMed ID: 28763002
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interleukin-6 Deficiency Does Not Affect Motor Neuron Disease Caused by Superoxide Dismutase 1 Mutation.
    Han Y; Ripley B; Serada S; Naka T; Fujimoto M
    PLoS One; 2016; 11(4):e0153399. PubMed ID: 27070121
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NR1D1 downregulation in astrocytes induces a phenotype that is detrimental to cocultured motor neurons.
    Killoy KM; Harlan BA; Pehar M; Vargas MR
    FASEB J; 2022 Apr; 36(4):e22262. PubMed ID: 35319791
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Spinal inhibitory interneuron pathology follows motor neuron degeneration independent of glial mutant superoxide dismutase 1 expression in SOD1-ALS mice.
    Hossaini M; Cardona Cano S; van Dis V; Haasdijk ED; Hoogenraad CC; Holstege JC; Jaarsma D
    J Neuropathol Exp Neurol; 2011 Aug; 70(8):662-77. PubMed ID: 21760539
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis.
    Parone PA; Da Cruz S; Han JS; McAlonis-Downes M; Vetto AP; Lee SK; Tseng E; Cleveland DW
    J Neurosci; 2013 Mar; 33(11):4657-71. PubMed ID: 23486940
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.