BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

249 related articles for article (PubMed ID: 29309644)

  • 1. PIDD mediates the association of DNA-PKcs and ATR at stalled replication forks to facilitate the ATR signaling pathway.
    Lin YF; Shih HY; Shang ZF; Kuo CT; Guo J; Du C; Lee H; Chen BPC
    Nucleic Acids Res; 2018 Feb; 46(4):1847-1859. PubMed ID: 29309644
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response.
    Lin YF; Shih HY; Shang Z; Matsunaga S; Chen BP
    Nucleic Acids Res; 2014 Apr; 42(7):4463-73. PubMed ID: 24500207
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ATR-dependent phosphorylation of DNA-dependent protein kinase catalytic subunit in response to UV-induced replication stress.
    Yajima H; Lee KJ; Chen BP
    Mol Cell Biol; 2006 Oct; 26(20):7520-8. PubMed ID: 16908529
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.
    Falck J; Coates J; Jackson SP
    Nature; 2005 Mar; 434(7033):605-11. PubMed ID: 15758953
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress.
    Liu S; Opiyo SO; Manthey K; Glanzer JG; Ashley AK; Amerin C; Troksa K; Shrivastav M; Nickoloff JA; Oakley GG
    Nucleic Acids Res; 2012 Nov; 40(21):10780-94. PubMed ID: 22977173
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibiting DNA-PKcs in a non-homologous end-joining pathway in response to DNA double-strand breaks.
    Dong J; Zhang T; Ren Y; Wang Z; Ling CC; He F; Li GC; Wang C; Wen B
    Oncotarget; 2017 Apr; 8(14):22662-22673. PubMed ID: 28186989
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases.
    Yajima H; Lee KJ; Zhang S; Kobayashi J; Chen BP
    J Mol Biol; 2009 Jan; 385(3):800-10. PubMed ID: 19071136
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The N-terminal region of the DNA-dependent protein kinase catalytic subunit is required for its DNA double-stranded break-mediated activation.
    Davis AJ; Lee KJ; Chen DJ
    J Biol Chem; 2013 Mar; 288(10):7037-46. PubMed ID: 23322783
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ATR and H2AX cooperate in maintaining genome stability under replication stress.
    Chanoux RA; Yin B; Urtishak KA; Asare A; Bassing CH; Brown EJ
    J Biol Chem; 2009 Feb; 284(9):5994-6003. PubMed ID: 19049966
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ATR Contributes More Than ATM in Intra-S-Phase Checkpoint Activation after IR, and DNA-PKcs Facilitates Recovery: Evidence for Modular Integration of ATM/ATR/DNA-PKcs Functions.
    Soni A; Duan X; Stuschke M; Iliakis G
    Int J Mol Sci; 2022 Jul; 23(14):. PubMed ID: 35886852
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA-Dependent Protein Kinase Catalytic Subunit: The Sensor for DNA Double-Strand Breaks Structurally and Functionally Related to Ataxia Telangiectasia Mutated.
    Matsumoto Y; Asa ADDC; Modak C; Shimada M
    Genes (Basel); 2021 Jul; 12(8):. PubMed ID: 34440313
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The catalytic subunit of DNA-dependent protein kinase is required for cellular resistance to oxidative stress independent of DNA double-strand break repair.
    Li M; Lin YF; Palchik GA; Matsunaga S; Wang D; Chen BP
    Free Radic Biol Med; 2014 Nov; 76():278-85. PubMed ID: 25224041
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex.
    Hammel M; Yu Y; Radhakrishnan SK; Chokshi C; Tsai MS; Matsumoto Y; Kuzdovich M; Remesh SG; Fang S; Tomkinson AE; Lees-Miller SP; Tainer JA
    J Biol Chem; 2016 Dec; 291(53):26987-27006. PubMed ID: 27875301
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition.
    Middleton FK; Patterson MJ; Elstob CJ; Fordham S; Herriott A; Wade MA; McCormick A; Edmondson R; May FE; Allan JM; Pollard JR; Curtin NJ
    Oncotarget; 2015 Oct; 6(32):32396-409. PubMed ID: 26486089
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Replication independent ATR signalling leads to G2/M arrest requiring Nbs1, 53BP1 and MDC1.
    Stiff T; Cerosaletti K; Concannon P; O'Driscoll M; Jeggo PA
    Hum Mol Genet; 2008 Oct; 17(20):3247-53. PubMed ID: 18664457
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM).
    Zhou Y; Paull TT
    J Biol Chem; 2013 Dec; 288(52):37112-25. PubMed ID: 24220101
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double strand breaks.
    Tomimatsu N; Tahimic CG; Otsuki A; Burma S; Fukuhara A; Sato K; Shiota G; Oshimura M; Chen DJ; Kurimasa A
    J Biol Chem; 2007 Apr; 282(14):10138-45. PubMed ID: 17272272
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA structure-specific priming of ATR activation by DNA-PKcs.
    Vidal-Eychenié S; Décaillet C; Basbous J; Constantinou A
    J Cell Biol; 2013 Aug; 202(3):421-9. PubMed ID: 23897887
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of ATR-dependent feedback activation of Chk1 sensitises cancer cells to Chk1 inhibitor monotherapy.
    Massey AJ
    Cancer Lett; 2016 Dec; 383(1):41-52. PubMed ID: 27693461
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deciphering the role of distinct DNA-PK phosphorylations at collapsed replication forks.
    Neal JA; Dunger K; Geith K; Meek K
    DNA Repair (Amst); 2020 Oct; 94():102925. PubMed ID: 32674014
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.