BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 29311509)

  • 1. 7-Azaindole: A Versatile Scaffold for Developing Kinase Inhibitors.
    Irie T; Sawa M
    Chem Pharm Bull (Tokyo); 2018; 66(1):29-36. PubMed ID: 29311509
    [TBL] [Abstract][Full Text] [Related]  

  • 2. N-substituted azaindoles as potent inhibitors of Cdc7 kinase.
    Bryan MC; Falsey JR; Frohn M; Reichelt A; Yao G; Bartberger MD; Bailis JM; Zalameda L; Miguel TS; Doherty EM; Allen JG
    Bioorg Med Chem Lett; 2013 Apr; 23(7):2056-60. PubMed ID: 23481650
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and evaluation of 7-azaindole derivatives bearing benzocycloalkanone motifs as protein kinase inhibitors.
    Qhobosheane MA; Legoabe LJ; Josselin B; Bach S; Ruchaud S; Petzer JP; Beteck RM
    Bioorg Med Chem; 2020 Jun; 28(11):115468. PubMed ID: 32284225
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ROCK inhibitors 3: Design, synthesis and structure-activity relationships of 7-azaindole-based Rho kinase (ROCK) inhibitors.
    Bandarage UK; Cao J; Come JH; Court JJ; Gao H; Jacobs MD; Marhefka C; Nanthakumar S; Green J
    Bioorg Med Chem Lett; 2018 Aug; 28(15):2622-2626. PubMed ID: 30082069
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ROCK inhibitors 4: Structure-activity relationship studies of 7-azaindole-based rho kinase (ROCK) inhibitors.
    Bandarage UK; Court J; Gao H; Nanthakumar S; Come JH; Giroux S; Green J
    Bioorg Med Chem Lett; 2021 Feb; 33():127721. PubMed ID: 33259926
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and evaluation of a series of 4-azaindole-containing p21-activated kinase-1 inhibitors.
    Lee W; Crawford JJ; Aliagas I; Murray LJ; Tay S; Wang W; Heise CE; Hoeflich KP; La H; Mathieu S; Mintzer R; Ramaswamy S; Rouge L; Rudolph J
    Bioorg Med Chem Lett; 2016 Aug; 26(15):3518-24. PubMed ID: 27346791
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Azaindole derivatives as potential kinase inhibitors and their SARs elucidation.
    Fang G; Chen H; Cheng Z; Tang Z; Wan Y
    Eur J Med Chem; 2023 Oct; 258():115621. PubMed ID: 37423125
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Developing DYRK inhibitors derived from the meridianins as a means of increasing levels of NFAT in the nucleus.
    Shaw SJ; Goff DA; Lin N; Singh R; Li W; McLaughlin J; Baltgalvis KA; Payan DG; Kinsella TM
    Bioorg Med Chem Lett; 2017 Jun; 27(11):2617-2621. PubMed ID: 28408219
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovering novel 7-azaindole-based series as potent AXL kinase inhibitors.
    Feneyrolles C; Guiet L; Singer M; Van Hijfte N; Daydé-Cazals B; Fauvel B; Chevé G; Yasri A
    Bioorg Med Chem Lett; 2017 Feb; 27(4):862-866. PubMed ID: 28094183
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening.
    Jung ME; Byun BJ; Kim HM; Lee JY; Park JH; Lee N; Son YH; Choi SU; Yang KM; Kim SJ; Lee K; Kim YC; Choi G
    Bioorg Med Chem Lett; 2016 Jun; 26(11):2719-23. PubMed ID: 27106709
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rational Design, Synthesis, and Biological Evaluation of 7-Azaindole Derivatives as Potent Focused Multi-Targeted Kinase Inhibitors.
    Daydé-Cazals B; Fauvel B; Singer M; Feneyrolles C; Bestgen B; Gassiot F; Spenlinhauer A; Warnault P; Van Hijfte N; Borjini N; Chevé G; Yasri A
    J Med Chem; 2016 Apr; 59(8):3886-905. PubMed ID: 27010810
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of novel 7-azaindoles as PDK1 inhibitors.
    Wucherer-Plietker M; Merkul E; Müller TJJ; Esdar C; Knöchel T; Heinrich T; Buchstaller HP; Greiner H; Dorsch D; Finsinger D; Calderini M; Bruge D; Grädler U
    Bioorg Med Chem Lett; 2016 Jul; 26(13):3073-3080. PubMed ID: 27217002
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Indolinone based LRRK2 kinase inhibitors with a key hydrogen bond.
    Göring S; Taymans JM; Baekelandt V; Schmidt B
    Bioorg Med Chem Lett; 2014 Oct; 24(19):4630-4637. PubMed ID: 25219901
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 1: design, synthesis and biological activity.
    Islam I; Bryant J; Chou YL; Kochanny MJ; Lee W; Phillips GB; Yu H; Adler M; Whitlow M; Ho E; Lentz D; Polokoff MA; Subramanyam B; Wu JM; Zhu D; Feldman RI; Arnaiz DO
    Bioorg Med Chem Lett; 2007 Jul; 17(14):3814-8. PubMed ID: 17531483
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Recent advances of pyrrolopyridines derivatives: a patent and literature review.
    El-Gamal MI; Anbar HS
    Expert Opin Ther Pat; 2017 May; 27(5):591-606. PubMed ID: 28064544
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification, synthesis and evaluation of CSF1R inhibitors using fragment based drug design.
    Machiraju PK; Yedla P; Gubbala SP; Bohari T; Abdul JKV; Xu S; Patel R; Chittireddy VRR; Boppana K; Jagarlapudi SARP; Neamati N; Syed R; Amanchy R
    Comput Biol Chem; 2019 Jun; 80():374-383. PubMed ID: 31103918
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Binding free-energy calculation is a powerful tool for drug optimization: calculation and measurement of binding free energy for 7-azaindole derivatives to glycogen synthase kinase-3β.
    Kitamura K; Tamura Y; Ueki T; Ogata K; Noda S; Himeno R; Chuman H
    J Chem Inf Model; 2014 Jun; 54(6):1653-60. PubMed ID: 24884406
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of 4-azaindoles as novel inhibitors of c-Met kinase.
    Porter J; Lumb S; Franklin RJ; Gascon-Simorte JM; Calmiano M; Riche KL; Lallemand B; Keyaerts J; Edwards H; Maloney A; Delgado J; King L; Foley A; Lecomte F; Reuberson J; Meier C; Batchelor M
    Bioorg Med Chem Lett; 2009 May; 19(10):2780-4. PubMed ID: 19369077
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: wild type and mutant (L1196M) active compounds with unique binding mode.
    Gummadi VR; Rajagopalan S; Looi CY; Paydar M; Renukappa GA; Ainan BR; Krishnamurthy NR; Panigrahi SK; Mahasweta K; Raghuramachandran S; Rajappa M; Ramanathan A; Lakshminarasimhan A; Ramachandra M; Wong PF; Mustafa MR; Nanduri S; Hosahalli S
    Bioorg Med Chem Lett; 2013 Sep; 23(17):4911-8. PubMed ID: 23880539
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.
    Kusakabe K; Ide N; Daigo Y; Itoh T; Yamamoto T; Kojima E; Mitsuoka Y; Tadano G; Tagashira S; Higashino K; Okano Y; Sato Y; Inoue M; Iguchi M; Kanazawa T; Ishioka Y; Dohi K; Kido Y; Sakamoto S; Ando S; Maeda M; Higaki M; Yoshizawa H; Murai H; Nakamura Y
    Bioorg Med Chem; 2015 May; 23(9):2247-60. PubMed ID: 25801152
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.