182 related articles for article (PubMed ID: 29311509)
21. Discovery of novel 7-azaindole derivatives bearing dihydropyridazine moiety as c-Met kinase inhibitors.
Tang Q; Wang L; Duan Y; Wang W; Huang S; Zhi J; Jia S; Zhu W; Wang P; Luo R; Zheng P
Eur J Med Chem; 2017 Jun; 133():97-106. PubMed ID: 28384549
[TBL] [Abstract][Full Text] [Related]
22. 7-Azaindole Analogues as Bioactive Agents and Recent Results.
Sharma N; Anurag
Mini Rev Med Chem; 2019; 19(9):727-736. PubMed ID: 30264679
[TBL] [Abstract][Full Text] [Related]
23. Structure-based de novo design and identification of D816V mutant-selective c-KIT inhibitors.
Park H; Lee S; Lee S; Hong S
Org Biomol Chem; 2014 Jul; 12(26):4644-55. PubMed ID: 24853767
[TBL] [Abstract][Full Text] [Related]
24. The azaindole framework in the design of kinase inhibitors.
Mérour JY; Buron F; Plé K; Bonnet P; Routier S
Molecules; 2014 Nov; 19(12):19935-79. PubMed ID: 25460315
[TBL] [Abstract][Full Text] [Related]
25. Design and synthesis of potent and selective azaindole-based Rho kinase (ROCK) inhibitors.
Schirok H; Kast R; Figueroa-Pérez S; Bennabi S; Gnoth MJ; Feurer A; Heckroth H; Thutewohl M; Paulsen H; Knorr A; Hütter J; Lobell M; Münter K; Geiss V; Ehmke H; Lang D; Radtke M; Mittendorf J; Stasch JP
ChemMedChem; 2008 Dec; 3(12):1893-904. PubMed ID: 18973168
[TBL] [Abstract][Full Text] [Related]
26. Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes.
Eduful BJ; O'Byrne SN; Temme L; Asquith CRM; Liang Y; Picado A; Pilotte JR; Hossain MA; Wells CI; Zuercher WJ; Catta-Preta CMC; Zonzini Ramos P; Santiago AS; Couñago RM; Langendorf CG; Nay K; Oakhill JS; Pulliam TL; Lin C; Awad D; Willson TM; Frigo DE; Scott JW; Drewry DH
J Med Chem; 2021 Aug; 64(15):10849-10877. PubMed ID: 34264658
[TBL] [Abstract][Full Text] [Related]
27. Janus kinase 2 inhibitors. Synthesis and characterization of a novel polycyclic azaindole.
Wang T; Duffy JP; Wang J; Halas S; Salituro FG; Pierce AC; Zuccola HJ; Black JR; Hogan JK; Jepson S; Shlyakter D; Mahajan S; Gu Y; Hoock T; Wood M; Furey BF; Frantz JD; Dauffenbach LM; Germann UA; Fan B; Namchuk M; Bennani YL; Ledeboer MW
J Med Chem; 2009 Dec; 52(24):7938-41. PubMed ID: 20014869
[TBL] [Abstract][Full Text] [Related]
28. Synthesis and evaluation of C3 substituted chalcone-based derivatives of 7-azaindole as protein kinase inhibitors.
Qhobosheane MA; Legoabe LJ; Josselin B; Bach S; Ruchaud S; Beteck RM
Chem Biol Drug Des; 2020 Dec; 96(6):1395-1407. PubMed ID: 32558155
[TBL] [Abstract][Full Text] [Related]
29. A novel chemotype of kinase inhibitors: Discovery of 3,4-ring fused 7-azaindoles and deazapurines as potent JAK2 inhibitors.
Wang T; Ledeboer MW; Duffy JP; Salituro FG; Pierce AC; Zuccola HJ; Block E; Shlyakter D; Hogan JK; Bennani YL
Bioorg Med Chem Lett; 2010 Jan; 20(1):153-6. PubMed ID: 19945871
[TBL] [Abstract][Full Text] [Related]
30. Exploration of diverse hinge-binding scaffolds for selective Aurora kinase inhibitors.
Ji Z; Dai Y; Abad-Zapatero C; Albert DH; Bouska JJ; Glaser KB; Marcotte PA; Soni NB; Magoc TJ; Stewart KD; Wei RQ; Davidsen SK; Michaelides MR
Bioorg Med Chem Lett; 2012 Jul; 22(14):4528-31. PubMed ID: 22727637
[TBL] [Abstract][Full Text] [Related]
31. Exploration of 7-azaindole-coumaranone hybrids and their analogues as protein kinase inhibitors.
Qhobosheane MA; Beteck RM; Baratte B; Robert T; Ruchaud S; Bach S; Legoabe LJ
Chem Biol Interact; 2021 Jul; 343():109478. PubMed ID: 33905741
[TBL] [Abstract][Full Text] [Related]
32. Limited Proteolysis Combined with Stable Isotope Labeling Reveals Conformational Changes in Protein (Pseudo)kinases upon Binding Small Molecules.
Di Michele M; Stes E; Vandermarliere E; Arora R; Astorga-Wells J; Vandenbussche J; van Heerde E; Zubarev R; Bonnet P; Linders JT; Jacoby E; Brehmer D; Martens L; Gevaert K
J Proteome Res; 2015 Oct; 14(10):4179-93. PubMed ID: 26293246
[TBL] [Abstract][Full Text] [Related]
33. Fragment-based design, synthesis, biological evaluation, and SAR of 1H-benzo[d]imidazol-2-yl)-1H-indazol derivatives as potent PDK1 inhibitors.
Chen T; Sorna V; Choi S; Call L; Bearss J; Carpenter K; Warner SL; Sharma S; Bearss DJ; Vankayalapati H
Bioorg Med Chem Lett; 2017 Dec; 27(24):5473-5480. PubMed ID: 29150397
[TBL] [Abstract][Full Text] [Related]
34. Discovery of N-substituted 7-azaindoles as PIM1 kinase inhibitors - Part I.
Barberis C; Moorcroft N; Arendt C; Levit M; Moreno-Mazza S; Batchelor J; Mechin I; Majid T
Bioorg Med Chem Lett; 2017 Oct; 27(20):4730-4734. PubMed ID: 28947155
[TBL] [Abstract][Full Text] [Related]
35. Synthesis of new pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs as DYRK1A inhibitors.
Bruel A; Bénéteau R; Chabanne M; Lozach O; Le Guevel R; Ravache M; Bénédetti H; Meijer L; Logé C; Robert JM
Bioorg Med Chem Lett; 2014 Nov; 24(21):5037-40. PubMed ID: 25248682
[TBL] [Abstract][Full Text] [Related]
36. Current Fragment-to-lead Approaches Starting from the 7-azaindole: The Pharmacological Versatility of a Privileged Molecular Fragment.
Marcos Santos L; da Silveira NJF
Curr Top Med Chem; 2023; 23(22):2116-2130. PubMed ID: 37461366
[TBL] [Abstract][Full Text] [Related]
37. Approved Small-Molecule ATP-Competitive Kinases Drugs Containing Indole/Azaindole/Oxindole Scaffolds: R&D and Binding Patterns Profiling.
Zhang H; He F; Gao G; Lu S; Wei Q; Hu H; Wu Z; Fang M; Wang X
Molecules; 2023 Jan; 28(3):. PubMed ID: 36770611
[TBL] [Abstract][Full Text] [Related]
38. Divergent synthesis of kinase inhibitor derivatives, leading to discovery of selective Gck inhibitors.
Matsumaru T; Inai M; Ishigami K; Iwamatsu T; Maita H; Otsuguro S; Nomura T; Matsuda A; Ichikawa S; Sakaitani M; Shuto S; Maenaka K; Kan T
Bioorg Med Chem Lett; 2017 May; 27(10):2144-2147. PubMed ID: 28385506
[TBL] [Abstract][Full Text] [Related]
39. Selection of fragments for kinase inhibitor design: decoration is key.
Czodrowski P; Hölzemann G; Barnickel G; Greiner H; Musil D
J Med Chem; 2015 Jan; 58(1):457-65. PubMed ID: 25437144
[TBL] [Abstract][Full Text] [Related]
40. Kinase hinge binding scaffolds and their hydrogen bond patterns.
Xing L; Klug-Mcleod J; Rai B; Lunney EA
Bioorg Med Chem; 2015 Oct; 23(19):6520-7. PubMed ID: 26358279
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]