326 related articles for article (PubMed ID: 29311706)
1. Mechanistic insights into remodeled Tau-derived PHF6 peptide fibrils by Naphthoquinone-Tryptophan hybrids.
KrishnaKumar VG; Paul A; Gazit E; Segal D
Sci Rep; 2018 Jan; 8(1):71. PubMed ID: 29311706
[TBL] [Abstract][Full Text] [Related]
2. Antagonistic Activity of Naphthoquinone-Based Hybrids toward Amyloids Associated with Alzheimer's Disease and Type-2 Diabetes.
Paul A; Viswanathan GK; Mahapatra S; Balboni G; Pacifico S; Gazit E; Segal D
ACS Chem Neurosci; 2019 Aug; 10(8):3510-3520. PubMed ID: 31282646
[TBL] [Abstract][Full Text] [Related]
3. Integrating in vitro and in silico approaches to evaluate the "dual functionality" of palmatine chloride in inhibiting and disassembling Tau-derived VQIVYK peptide fibrils.
Haj E; Losev Y; Guru KrishnaKumar V; Pichinuk E; Engel H; Raveh A; Gazit E; Segal D
Biochim Biophys Acta Gen Subj; 2018 Jul; 1862(7):1565-1575. PubMed ID: 29634991
[TBL] [Abstract][Full Text] [Related]
4. Cl-NQTrp Alleviates Tauopathy Symptoms in a Model Organism through the Inhibition of Tau Aggregation-Engendered Toxicity.
Frenkel-Pinter M; Tal S; Scherzer-Attali R; Abu-Hussien M; Alyagor I; Eisenbaum T; Gazit E; Segal D
Neurodegener Dis; 2017; 17(2-3):73-82. PubMed ID: 27760426
[TBL] [Abstract][Full Text] [Related]
5. An amyloidogenic hexapeptide from the cataract-associated γD-crystallin is a model for the full-length protein and is inhibited by naphthoquinone-tryptophan hybrids.
Abu-Hussien M; Viswanathan GK; Haj E; Paul A; Gazit E; Segal D
Int J Biol Macromol; 2020 Aug; 157():424-433. PubMed ID: 32302630
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of tau amyloid formation and disruption of its preformed fibrils by Naphthoquinone-Dopamine hybrid.
Paul A; Viswanathan GK; Huber A; Arad E; Engel H; Jelinek R; Gazit E; Segal D
FEBS J; 2021 Jul; 288(14):4267-4290. PubMed ID: 33523571
[TBL] [Abstract][Full Text] [Related]
7. Naphthoquinone-Tryptophan Hybrid Inhibits Aggregation of the Tau-Derived Peptide PHF6 and Reduces Neurotoxicity.
Frenkel-Pinter M; Tal S; Scherzer-Attali R; Abu-Hussien M; Alyagor I; Eisenbaum T; Gazit E; Segal D
J Alzheimers Dis; 2016; 51(1):165-78. PubMed ID: 26836184
[TBL] [Abstract][Full Text] [Related]
8. Purpurin modulates Tau-derived VQIVYK fibrillization and ameliorates Alzheimer's disease-like symptoms in animal model.
Viswanathan GK; Shwartz D; Losev Y; Arad E; Shemesh C; Pichinuk E; Engel H; Raveh A; Jelinek R; Cooper I; Gosselet F; Gazit E; Segal D
Cell Mol Life Sci; 2020 Jul; 77(14):2795-2813. PubMed ID: 31562564
[TBL] [Abstract][Full Text] [Related]
9. Atomistic mechanism of polyphenol amyloid aggregation inhibitors: molecular dynamics study of Curcumin, Exifone, and Myricetin interaction with the segment of tau peptide oligomer.
Berhanu WM; Masunov AE
J Biomol Struct Dyn; 2015; 33(7):1399-411. PubMed ID: 25093402
[TBL] [Abstract][Full Text] [Related]
10. Dependence of the Formation of Tau and Aβ Peptide Mixed Aggregates on the Secondary Structure of the N-Terminal Region of Aβ.
Rojas AV; Maisuradze GG; Scheraga HA
J Phys Chem B; 2018 Jul; 122(28):7049-7056. PubMed ID: 29940109
[TBL] [Abstract][Full Text] [Related]
11. Methylations of tryptophan-modified naphthoquinone affect its inhibitory potential toward Aβ aggregation.
Scherzer-Attali R; Convertino M; Pellarin R; Gazit E; Segal D; Caflisch A
J Phys Chem B; 2013 Feb; 117(6):1780-9. PubMed ID: 23259849
[TBL] [Abstract][Full Text] [Related]
12. Resonance Raman spectroscopic measurements delineate the structural changes that occur during tau fibril formation.
Ramachandran G; Milán-Garcés EA; Udgaonkar JB; Puranik M
Biochemistry; 2014 Oct; 53(41):6550-65. PubMed ID: 25284680
[TBL] [Abstract][Full Text] [Related]
13. Primary Fibril Nucleation of Aggregation Prone Tau Fragments PHF6 and PHF6.
Smit FX; Luiken JA; Bolhuis PG
J Phys Chem B; 2017 Apr; 121(15):3250-3261. PubMed ID: 27776213
[TBL] [Abstract][Full Text] [Related]
14. Sequence-dependent abnormal aggregation of human Tau fragment in an inducible cell model.
Liu XL; Hu JY; Hu MY; Zhang Y; Hong ZY; Cheng XQ; Chen J; Pang DW; Liang Y
Biochim Biophys Acta; 2015 Aug; 1852(8):1561-73. PubMed ID: 25912737
[TBL] [Abstract][Full Text] [Related]
15. Inhibitory Effect of Naphthoquinone-Tryptophan Hybrid towards Aggregation of PAP f39 Semen Amyloid.
Viswanathan GK; Mohapatra S; Paul A; Arad E; Jelinek R; Gazit E; Segal D
Molecules; 2018 Dec; 23(12):. PubMed ID: 30544943
[TBL] [Abstract][Full Text] [Related]
16. Disclosing the Mechanism of Spontaneous Aggregation and Template-Induced Misfolding of the Key Hexapeptide (PHF6) of Tau Protein Based on Molecular Dynamics Simulation.
Liu H; Zhong H; Liu X; Zhou S; Tan S; Liu H; Yao X
ACS Chem Neurosci; 2019 Dec; 10(12):4810-4823. PubMed ID: 31661961
[TBL] [Abstract][Full Text] [Related]
17. Interplay of isoform 1N4R tau protein and amyloid-β peptide fragment 25-35 in reducing and non-reducing conditions.
Mohammadi F; Takalloo Z; Rahmani H; Nasiri Khalili MA; Khajeh K; Riazi G; H Sajedi R
J Biochem; 2021 Feb; 169(1):119-134. PubMed ID: 32857841
[TBL] [Abstract][Full Text] [Related]
18. Deciphering the Inhibitory Mechanism of Naphthoquinone-Dopamine on the Aggregation of Tau Core Fragments PHF6* and PHF6.
Zou Y; Qi B; Tan J; Guan L; Zhang Q; Sun Y; Huang F
ACS Chem Neurosci; 2023 Sep; 14(17):3265-3277. PubMed ID: 37585669
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of the Aggregation and Toxicity of the Minimal Amyloidogenic Fragment of Tau by Its Pro-Substituted Analogues.
Chemerovski-Glikman M; Frenkel-Pinter M; Mdah R; Abu-Mokh A; Gazit E; Segal D
Chemistry; 2017 Jul; 23(40):9618-9624. PubMed ID: 28544138
[TBL] [Abstract][Full Text] [Related]
20. Charge-pairing mechanism of phosphorylation effect upon amyloid fibrillation of human tau core peptide.
Inoue M; Hirata A; Tainaka K; Morii T; Konno T
Biochemistry; 2008 Nov; 47(45):11847-57. PubMed ID: 18922026
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
