These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Inhibition of Sonic hedgehog and Notch pathways enhances sensitivity of CD133(+) glioma stem cells to temozolomide therapy. Ulasov IV; Nandi S; Dey M; Sonabend AM; Lesniak MS Mol Med; 2011; 17(1-2):103-12. PubMed ID: 20957337 [TBL] [Abstract][Full Text] [Related]
4. Cyclopamine treatment of human embryonic stem cells followed by culture in human astrocyte medium promotes differentiation into nestin- and GFAP-expressing astrocytic lineage. Lee DS; Yu K; Rho JY; Lee E; Han JS; Koo DB; Cho YS; Kim J; Lee KK; Han YM Life Sci; 2006 Dec; 80(2):154-9. PubMed ID: 17028036 [TBL] [Abstract][Full Text] [Related]
5. Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma. Bar EE; Chaudhry A; Lin A; Fan X; Schreck K; Matsui W; Piccirillo S; Vescovi AL; DiMeco F; Olivi A; Eberhart CG Stem Cells; 2007 Oct; 25(10):2524-33. PubMed ID: 17628016 [TBL] [Abstract][Full Text] [Related]
6. Cyclopamine sensitizes glioblastoma cells to temozolomide treatment through Sonic hedgehog pathway. Carballo GB; Matias D; Ribeiro JH; Pessoa LS; Arrais-Neto AM; Spohr TCLSE Life Sci; 2020 Sep; 257():118027. PubMed ID: 32622951 [TBL] [Abstract][Full Text] [Related]
7. Sonic Hedgehog inhibition as a strategy to augment radiosensitivity of hepatocellular carcinoma. Tsai CL; Hsu FM; Tzen KY; Liu WL; Cheng AL; Cheng JC J Gastroenterol Hepatol; 2015 Aug; 30(8):1317-24. PubMed ID: 25682950 [TBL] [Abstract][Full Text] [Related]
8. Inhibition of hedgehog signaling depresses self-renewal of pancreatic cancer stem cells and reverses chemoresistance. Huang FT; Zhuan-Sun YX; Zhuang YY; Wei SL; Tang J; Chen WB; Zhang SN Int J Oncol; 2012 Nov; 41(5):1707-14. PubMed ID: 22923052 [TBL] [Abstract][Full Text] [Related]
9. Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells. Elamin MH; Shinwari Z; Hendrayani SF; Al-Hindi H; Al-Shail E; Khafaga Y; Al-Kofide A; Aboussekhra A Mol Carcinog; 2010 Mar; 49(3):302-14. PubMed ID: 20025076 [TBL] [Abstract][Full Text] [Related]
10. Cyclopamine bioactivity by extraction method from Veratrum californicum. Turner MW; Cruz R; Mattos J; Baughman N; Elwell J; Fothergill J; Nielsen A; Brookhouse J; Bartlett A; Malek P; Pu X; King MD; McDougal OM Bioorg Med Chem; 2016 Aug; 24(16):3752-7. PubMed ID: 27338657 [TBL] [Abstract][Full Text] [Related]
11. In vitro and in vivo characterization of a novel Hedgehog signaling antagonist in human glioblastoma cell lines. Ferruzzi P; Mennillo F; De Rosa A; Giordano C; Rossi M; Benedetti G; Magrini R; Pericot Mohr Gl; Miragliotta V; Magnoni L; Mori E; Thomas R; Tunici P; Bakker A Int J Cancer; 2012 Jul; 131(2):E33-44. PubMed ID: 22072503 [TBL] [Abstract][Full Text] [Related]
12. Expression of sonic hedgehog signaling components in hepatocellular carcinoma and cyclopamine-induced apoptosis through Bcl-2 downregulation in vitro. Chen XL; Cheng QY; She MR; Wang Q; Huang XH; Cao LQ; Fu XH; Chen JS Arch Med Res; 2010 Jul; 41(5):315-23. PubMed ID: 20851287 [TBL] [Abstract][Full Text] [Related]
13. The sonic hedgehog signaling pathway stimulates anaplastic thyroid cancer cell motility and invasiveness by activating Akt and c-Met. Williamson AJ; Doscas ME; Ye J; Heiden KB; Xing M; Li Y; Prinz RA; Xu X Oncotarget; 2016 Mar; 7(9):10472-85. PubMed ID: 26859575 [TBL] [Abstract][Full Text] [Related]
14. Inhibition of hedgehog signaling attenuates carcinogenesis in vitro and increases necrosis of cholangiocellular carcinoma. El Khatib M; Kalnytska A; Palagani V; Kossatz U; Manns MP; Malek NP; Wilkens L; Plentz RR Hepatology; 2013 Mar; 57(3):1035-45. PubMed ID: 23172661 [TBL] [Abstract][Full Text] [Related]
16. Hedgehog targeting by cyclopamine suppresses head and neck squamous cell carcinoma and enhances chemotherapeutic effects. Mozet C; Stoehr M; Dimitrova K; Dietz A; Wichmann G Anticancer Res; 2013 Jun; 33(6):2415-24. PubMed ID: 23749890 [TBL] [Abstract][Full Text] [Related]
17. Astrocytes Decreased the Sensitivity of Glioblastoma Cells to Temozolomide and Bay 11-7082. Pustchi SE; Avci NG; Akay YM; Akay M Int J Mol Sci; 2020 Sep; 21(19):. PubMed ID: 32998285 [TBL] [Abstract][Full Text] [Related]
18. Evaluation of cytotoxic properties of a cyclopamine glucuronide prodrug in rat glioblastoma cells and tumors. Bensalma S; Chadeneau C; Legigan T; Renoux B; Gaillard A; de Boisvilliers M; Pinet-Charvet C; Papot S; Muller JM J Mol Neurosci; 2015 Jan; 55(1):51-61. PubMed ID: 25280457 [TBL] [Abstract][Full Text] [Related]
19. Design and synthesis of inhibitors of Hedgehog signaling based on the alkaloid cyclopamine. Winkler JD; Isaacs A; Holderbaum L; Tatard V; Dahmane N Org Lett; 2009 Jul; 11(13):2824-7. PubMed ID: 19552464 [TBL] [Abstract][Full Text] [Related]
20. Combination therapy with micellarized cyclopamine and temozolomide attenuate glioblastoma growth through Gli1 down-regulation. Liu YJ; Ma YC; Zhang WJ; Yang ZZ; Liang DS; Wu ZF; Qi XR Oncotarget; 2017 Jun; 8(26):42495-42509. PubMed ID: 28477008 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]